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Introduction Cluster analysis, a machine learning-based and data-driven technique for identifying groups in data, has demonstrated its potential in a wide range of contexts. However, critical appraisal and reproducibility are often limited by insufficient reporting, ultimately hampering the interpretation and trust of key stakeholders. The present paper describes the protocol that will guide the d
The European Spallation Source is currently under construction in Lund, Sweden. Consisting of a linear accelerator delivering an unprecedented 5 MW proton beam to the spallation source, i.e. a rotating Tungsten disk, it will deliver high-flux neutron beams to multiple beamlines at which scientific experiments will be conducted in many scientific disciplines.To simulate the proton beam and for crea
The transition from batch-wise to integrated continuous manufacturing of biopharmaceuticals has gained significant attention over the past decade. While this concept has been thoroughly studied, there remains significant room for improvement in terms of process automation and real-time monitoring. This study showcases the implementation of an integrated downstream process at a lab scale, operating
Insect pollinators are declining globally, partly due to agricultural intensification, which threatens biodiversity and ecosystem services. To help decision-makers make informed choices, a variety of tools such as softwares, websites and frameworks have been developed to guide pollinator-friendly management and conservation. However, the lack of a comprehensive overview of these tools limits stake
OBJECTIVE: To explore the associations between daily time in sedentary behaviour (SED) and physical activity (PA) with perceived physical capacity, health-related quality of life (HRQoL) and fatigue in persons with post COVID-19 condition (PCC). An additional objective was to describe changes in SED and PA levels over three months.MATERIALS AND METHODS: Individuals with PCC self-reported on physic
Covid-19 has triggered a massive global challenge with 1,576,069 overall confirmed cases, 1,545,429 recovered cases, and 30,640 deaths across Pakistan. Epidemiological models have always played an important role in understanding the dynamics of such infectious diseases. The severity of Covid-19 infection depends on several factors such as immune system and virus variants. Although detailed epidemi
Galaxies are complex objects, yet the number of independent parameters to describe them remains unknown. We present here a non-parametric method to estimate the intrinsic dimensionality of large data sets. We apply it to wide-band photometric data drawn from the COSMOS2020 catalogue and a comparable mock catalogue from the HORIZON-AGN simulation. Our galaxy catalogues are limited in signal-to-nois
Polarized fluorescence microscopy is a valuable tool for measuring molecular orientations in biological samples, but techniques for recovering three-dimensional orientations and positions of fluorescent ensembles are limited. We report a polarized dual-view light-sheet system for determining the diffraction-limited three-dimensional distribution of the orientations and positions of ensembles of fl
Climate change and the resulting warming caused by human activities, such as releasing greenhouse gases (GHG), notably carbon dioxide (CO2), are paramount concerns in the contemporary era. Therefore, it is essential to understand spatial and temporal variations of atmospheric carbon dioxide concentration (XCO2) on national and international scales and the role of controlling variables. This resear
Background We seek to clarify how changes in the prevalence of drug use disorder (DUD) in Sweden in the 1950-1990 birth cohort impact the aggregation and co-aggregation in siblings of DUD and alcohol use disorder (AUD). Methods We examined risk for DUD and AUD in siblings of 102,624 DUD cases and matched control probands and 123,837 AUD case and matched control probands identified using Swedish re
The architecture and masses of planetary systems in the habitable zone could be strongly influenced by the presence of outer giant planets. Here, we investigate the impact of outer giants on terrestrial planet formation, under the assumption that the final assembly of the planetary system is set by a giant impact phase. Utilizing a state-of-the-art N-body simulation software, GENGA, we interpret h
Objectives: Posttransplant infections may lead to dire consequences in immunocompromised organ recipients. Oral foci of infection are therefore often eliminated prior to solid organ transplantation to reduce posttransplant morbidity. However, despite increasing numbers of organ transplantations the necessity of pretransplant dental treatment and its effect on transplant outcome remains uncertain.
This study compares the performance of different models used to assess the local wind near-surface conditions at an agricultural site in Scania, southern Sweden. The methods are: (a) the WASP model (Wind Analysis and Application Program), (b) separate linear regressions of the two wind vector components, (c) a regression model based on vector correlation, and (d) linear regression of scalar wind.
This paper is an attempt to understand how people, in the daily practice of interacting with material culture, created, dealt with and interpreted complex and socially stressful historical processes. A 16th-century timber-framed burgher house, the Reformation and industrialization are the focus of attention. Today the house stands in a museum of cultural history in the south Scandinavian town of L
As the frequency of natural disasters increases, marked by hotter summers and abnormal ecological changes, climate issues have become impossible to ignore. People are taking to the streets, not only demanding greater awareness but also pushing for meaningful policy changes. This research investigates the relationship between protest events and policymaking within the EU between July 2018 and Decem
