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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192289 hits

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Ecological Fiscal Transfers (EFT) have recently gained attention as a promising instrument addressing public authorities to provide incentives for nature conservation. In parallel, both the EU and various European countries are exploring new mechanisms to mobilise funding to support biodiversity conservation. We develop a proposal for an EFT design within the supranational context of the EU and as

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Objective To explore genetic and lifestyle risk factors of MRI-defined brain infarcts (BI) in large population-based cohorts. Methods We performed meta-analyses of genome-wide association studies (GWAS) and examined associations of vascular risk factors and their genetic risk scores (GRS) with MRI-defined BI and a subset of BI, namely, small subcortical BI (SSBI), in 18 population-based cohorts (n

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Popular Abstract in Swedish Fåglar har fascinerat människor i århundraden. Färgen på deras fjädrar, deras flyghöjd och deras förmåga att fånga små byten har skapat den allmänna uppfattningen att fåglar har en fantastisk syn. Föreställningen att fåglar har skarpare syn än människor är väletablerad hos jägare och fiskare och finns att hitta i litteraturen. Det finns emellertid tusentals fågelarter oAvian eyes are big both in relative and absolute terms, thus the importance of vision to birds is obvious. Even though the general eye plan is rather conservative throughout the group, there is a great variation in visual capabilities. In this thesis I present four studies on different aspects of spatial vision in parrots, procellariiform seabirds and birds of prey. In Paper I we studied retinal g

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The long-lived, light-induced radical Y-D(.) of the Tyr161 residue in the D2 protein of Photosystem 11 (PSII) is known to magnetically interact with the CaMn4 cluster, situated similar to 30 angstrom away. In this study we report a transient step-change increase in YD EPR intensity upon the application of a single laser flash to S, state-synchronised PSII-enriched membranes from spinach. This tran

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Background and Purpose-It is disputed whether there are sex differences in management and outcome after stroke; early studies have shown inconsistent results. The objective of this study was to verify and explain differences between men and women in management and outcome after stroke in a national perspective. Methods-In 2001, 20 761 stroke patients were registered in Riks-Stroke, the national qu

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This study is ultimately concerned with the attainment of stable peace in international affairs. The notion of stable peace-understood as military conflict resolution being unthinkable, no matter the severity of a conflict-rivals traditional accounts of the logic of international relations. Confidence-certainty as to the intentions of another actor-are at the heart of stable peace relationships. I

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LKB1 is a master kinase that regulates metabolism and growth through adenosine monophosphate-activated protein kinase (AMPK) and 12 other closely related kinases. Liver-specific ablation of LKB1 causes increased glucose production in hepatocytes in vitro and hyperglycaemia in fasting mice in vivo. Here we report that the salt-inducible kinases (SIK1, 2 and 3), members of the AMPK-related kinase fa

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Vertebral fractures are associated with back pain and disability. There are, however, few prospective data looking at back pain and disability following identification of radiographic vertebral fracture. The aim of this analysis was to determine the impact of radiographically identified vertebral fracture on the subsequent occurrence of back pain and disability. Women aged 50 years and over were r

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In aqueous solutions hydrophobically modified polyethylene glycol (HM-PEG) forms a transient polymer network held together by intermolecular hydrophobic associations. In the present investigation we have used NMR-diffusometry to study how the addition of methylated alpha-cyclodextrin (M-alpha-CD) influences the polymer network. The addit on of M-alpha-CD resulted in an increased mean self-diffusio

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The main aim of this thesis is to reach a deeper understanding of how personality and core beliefs relate to the experience of quality of life in old age, with regard to shaping meaning and worth. The thesis has been developed using a dialogue with older person’s reality, as it is lived in daily life. The thesis includes four studies. Quantitative as well as qualitative methods were used for analy

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Here we report on the development of a proteomic platform utilizing a piezoelectric flow-through dispensing unit made from silicon microstructures. The use of a novel surface coating, where matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI MS) targets were uniformly precoated with a thin film of matrix/nitrocellulose, made the sample preparation straightforward an

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Myocardial perfusion imaging with single-photon emission computed tomography (SPECT) is useful for the evaluation of patients with known or suspected coronary artery disease. Parameters of interest are the reduction in the blood perfusion (severity) and the lesion volume (extent). The aim of this study was to evaluate these parameters, as calculated by automatic quantification software, for differ

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Two anionic fluorene-thiophene alternating copolymers, poly[9,9-bis(4-sulfonylbutoxyphenyl)fluorene-2,7-diyl-2,5-thienylene] (PBS-PFT) and poly [9,9-bis(4-sulfonylbutoxyphenyl)fluorene-2,7-diyl-2,2'-bithiophene-5,5'- diyl] (PBS-PF2T), have been synthesized and their solution behaviors in water studied by UV-vis absorption spectroscopy, fluorescence, and electrical conductivity and compared with th