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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193057 hits

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Both the nutritional and functional properties of starch are directly influenced by the molecular structure of its polymers: amylose and amylopectin. It is therefore important to have reproducible methods for quantifying the molecular size. In the first part of the thesis, the composition, crystallinity, degree of branching, morphological, thermal and pasting properties, and susceptibility of the

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Research on the development of preterm infant feeding behavior has focused mainly on bottlefeeding, using invasive methods or observations by professionals. In this study, a clinical method for observing breastfeeding was developed in collaboration between observers and mothers for the purpose of enabling neonatal personnel and mothers to describe developmental stages in preterm infant breastfeedi

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he UPPS-P model of impulsivity proposes that impulsivity comprises five distinct facets—negative urgency, positive urgency, lack of premeditation, lack of perseverance, and sensation seeking. The UPPS-P Impulsive Behavior Scale has been used to measure these facets. The purpose of the current study was to develop and evaluate the psychometric properties of a Swedish version of the 20-item UPPS-P I

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The European Spallation Source is currently under construction in Lund, Sweden. Consisting of a linear accelerator delivering an unprecedented 5 MW proton beam to the spallation source, i.e. a rotating Tungsten disk, it will deliver high-flux neutron beams to multiple beamlines at which scientific experiments will be conducted in many scientific disciplines.To simulate the proton beam and for crea

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The transition from batch-wise to integrated continuous manufacturing of biopharmaceuticals has gained significant attention over the past decade. While this concept has been thoroughly studied, there remains significant room for improvement in terms of process automation and real-time monitoring. This study showcases the implementation of an integrated downstream process at a lab scale, operating

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Polyethylene glycol (PEG) is commonly used in the conservation of wooden artifacts, but its presence adversely affects the accuracy of radiocarbon dating. It is therefore critical to have robust methods for the removal of PEG from heritage materials. This paper presents the results of an experiment designed to test a protocol for the removal of low molecular-weight PEG-400 from conserved wood. We

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Ulnar nerve entrapment at the elbow (UNE) is the second most common compression neuropathy in the upper limb. Immediate return-to-work (RTW) after surgery is seldom possible due to restrictions and recovery demands. We aimed to explore RTW after UNE surgery and investigate factors contributing to variations. A prospective study with patients undergoing primary UNE surgery was conducted. Treatment

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The implementation of low-carbon futures requires both the assembling of new technologies, and practices, as well as the ‘unmaking’ of extant high-carbon infrastructures. Here, we bring together geographical, STS, anthropological, and sociological thinking on time to re-conceptualise such processes of unmaking. We argue that a focus on temporalities is especially pertinent to the unmaking of mater

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BACKGROUND: Patients receiving intraoperative ventilation during general anesthesia often have low end-tidal CO2 (etCO2). We examined the association of intraoperative etCO2 levels with the occurrence of postoperative pulmonary complications (PPCs) in a conveniently-sized international, prospective study named 'Local ASsessment of Ventilatory management during General Anesthesia for Surgery' (LAS

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Purpose – This study explores how a public client as a focal firm enables value co-creation through orchestration that includes navigating and bridging knowledge, business and innovation ecosystems. Design/methodology/approach – The research is based on qualitative methods, with 25 semi-structured interviews being conducted with client representatives and project partners from four completed const

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PURPOSE OF REVIEW: To summarize and critically interpret new evidence (from the last 12-18 months) on the associations between obesity and breathlessness, including epidemiology, physiological mechanisms, diagnostic challenges, and treatment approaches.RECENT FINDINGS: Multiple large cohorts confirm that obesity is one of the strongest independent predictors of exertional breathlessness. Recent wo

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The electrification of the transportation sector is a central strategy for decarbonization, yet it raises concerns about the capacity of existing electric power grids to meet increasing demand. This thesis investigates the interaction between large-scale electrified vehicle fleets and the electric power system under the assumption of full transport electrification. The focus is on assessing the re

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The article examines Europeanisation processes at the Spanish University of Valladolid (UVa) in the years around Spain’s adhesion to the European Communities in 1986. This event has often been seen as key to the Spanish transition to democracy, which had begun after the death of Francisco Franco in 1975. Drawing on a variety of source materials, the article shows that Europeanisation at the UVa in

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Biological drugs such as tumor necrosis factor (TNFα) blockers are very successful and effective in therapy of chronic inflammatory disease. These blockers bind TNFα and inhibit its pro-inflammatory function. But unfortunately, biological drugs are immunogenic and prolonged treatment triggers the formation of anti-drug antibodies and neutralizing antibodies (NAbs). This reaction is associated with

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Antimalarial resistance has diminished the control over the spread of malaria worldwide. Initiated by the discovery of ferroquine, organometallic derivatives of chloroquine have been investigated against resistant strains of Plasmodium, but further work needs to be done. The aim of this project is to expand the available candidates of organometallic antimalarial drugs. In this project, six new org

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There are spatial elements and factors in every social activity. Physical environment in particular and its characteristics has a significant effect in the social decisions and outcomes of a location and of the residents of disadvantaged areas. These spatial elements and factors have been the main focus in many researches and studies about young people’s socio-economic statuses and achievements. T