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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 194340 hits
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The aim of the essay was to present the Stockholm Film Workshop (Filmverkstan, 1973–2001) and its significance as a transnational site of film production. The films and the filmmaking at the workshop are considered as part of a minor cinema film practice in David E. James’s sense. James’s theory is complemented by returning to Gilles Deleuze and Felix Guattari’s original concept of minor literatur
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Highly controlled particle-assisted growth of semiconductor nanowires has been performed for many years, and a number of novel nanowire-based devices have been demonstrated. Full control of the epitaxial growth is required to optimize the performance of devices, and gold seed particles are known to provide the most controlled growth. Successful nanowire growth from gold particles generated and dep
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Amylase testing has been used as a presumptive test for crime scene saliva for over three decades, mainly to locate saliva stains on surfaces. We have developed a saliva screening application for crime scene trace swabs, utilising an amylase sensitive paper (Phadebas((R)) Forensic Press test). Positive results were obtained for all tested dried saliva stains (0.5-32muL) with high or intermediate a
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A method for screening of ketone biotransformations was developed and applied to the identification of Baeyer-Villiger monooxygenase (BVMO) activity. The method was based on the formation of a purple coloured product on reaction between an enolizable ketone and 3,5-dinitrobenzoic acid in an alkaline solution. Absorbance of the colour decreased with the size of the cycloketone ring. Stoichiometric
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Uridine phosphorylase (UP), a key enzyme in the pyrimidine salvage pathway catalyzes the reversible phosphorolysis of uridine or 2'-deoxyuridine to uracil and ribose 1-phosphate or 2'-deoxyribose 1-phosphate. This enzyme belongs to the nucleoside phosphorylase I superfamily whose members show diverse specificity for nucleoside substrates. Phylogenetic analysis shows Streptococcus pyogenes uridine
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The aim of this study was to describe changes over time in the indications and outcomes of cataract surgery and to discuss optimal timing for the surgery.
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Background. Comparisons of different stakeholders' ratings of the quality of older people care can help to drive quality improvement. Aim. The aim was to compare staff, older care recipients' and their relatives' quality of care ratings. Design. Cross-sectional questionnaire surveys in 2003 and 2004, using a repeated measures design on an organizational level. Methods. Nursing staff, care recip
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In this article, we present the second case of a tongue carcinoma with distinct morphological similarities to a primary sclerosing sweat duct carcinoma of the skin. The tumor infiltrated deeply into the striated muscle and exhibited extensive peri- and intraneural growth. Neoplastic cells had mildly pleomorphic nuclei and displayed in addition to small cysts, distinct duct formation with a bilayer
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The ability to compare soil chemical data achieved by different chemical extraction methods is a necessity for an efficient long-term monitoring of soils and for comparisons of results from regional soil surveys with differing standard methods. This study compares two common, methods for analysis of soil chemical properties, the combination of soil extraction in 1.0 M NH4Cl and 1.0 M KCl and the s
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The thesis deals with determination of the post peak behaviour of wood in pure tension and pure shear. Furhermore, the "Fictitious Crack Model" (FCM), which is a nonlinear fracture mechanics model ; originally developed for description of crack propagation in concrete, is employed to demonstrate the advantages of non linear fracture mechanics. A testing arrangement is presented with which the comp
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The reaction pathways in the ammoxidation of propene and of propane over an Sb-V-oxide catalyst were studied by analyzing the modes of transient responses of reactants and products resulting from step changes from inert gas to reactant feed. The pathway from propane to acrylonitrile begins with the oxidative dehydrogenation of propane to form propene. After readsorption, the propene is then transf
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Background and Objectives The chemical basis of the subgroups of A is largely unknown. We used thin-layer chromatography immunochemical staining techniques together with a range of characterized monoclonal reagents to analyse glycolipids isolated from a variety of weak subgroups. Materials and Methods Glycolipids isolated from red cells collected from nine genetically defined individuals of the ra
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A chemiluminescence inummoassay for the detection of four heart marker proteins: myoglobin, creatine kinase mb [CKmb], troponin I [Tnl], and fatty acid-binding protein [FABP], was designed. The inummoassay was based on enzyme-linked immunosorbent assay [ELISA] and antibodies immobilized in glass capillaries pre-treated with 3-aminopropyltriethoxysilane. The protein bound to the antibody was detect
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The use of monoclonal antibodies (MAbs) in cytotoxic conjugates (radionuclides, toxins, or drugs) for targeting tumor cells is restricted due to toxicity in vital organs. Through improved tumor targeting, it is possible to administer larger amounts of such labeled MAbs, thus improving the ability to eradicate tumor cells without increased normal organ toxicity. Extracorporeal affinity adsorption t
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The aim of the study was to outline whether the influence by lifestyle factors on serum lipids was modified by the hormonal situation in middle-aged women. Six thousand nine hundred eight women, aged 50 to 59 years, participated in a health assessment program, including a serum lipid profile evaluation. The women were grouped according to their hormonal status into premenopausal (PM) (n = 492), po
