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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 194886 hits

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This paper explores Europeanization of the Czech Ministry of Foreign Affairs by looking at the impact of the Common Foreign and Security Policy (CFSP) on the Ministry. Despite being intergovernmental, voluntary, governed by treaties and not laws previous studies suggest that CFSP has an impact on the domestic arena. The analysis is based on the conceptual framework developed by Smith (2000) in whi

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The aim of this thesis is to investigate the following: − The influence of incident angle and frequency dependency of a ceiling absorber on room acoustic descriptors − How ceiling absorber properties influence room acoustic descriptors such as reverberation time and steady state sound pressure level − Whether steady state sound pressure level is more related to the statistical absorption coeffici

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The number of companies in Sweden has shown a significant increase over the last five years (www.bolagsverket.se). Data about these companies is an important asset for the customer relationship management market. In most business areas, users are in search for new customers. Companies, such as Lundalogik AB, provide a service, where the analysts can look for customers in an interactive environment

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Title: The use of art for branding purposes - A study of Louis Vuitton’s art collaborations Louis Vuitton’s creative director, Marc Jacobs, personally describes the fine arts as being higher up in the social hierarchy than fashion. After all, it is known as the ultimate luxury item. This essay will explore the way that the brand uses art in various ways as a means of branding. After extensive res

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Adaptive as well as innate immune responses contribute to the development of atherosclerosis. Studies performed in experimental animals have revealed that some of these immune responses are protective while others contribute to the progression of disease. These observations suggest that it may be possible to develop novel therapies for cardiovascular disease by selectively modulating such atheropr

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Background: The purpose of the present study was to elucidate the experiences of long-term oxygen therapy (LTOT) patients with a portable oxygen unit and to describe the patients' self-assessed health-related quality of life (HRQoL). Methods: The study employed a prospective cross-sectional design. Data collection entailed two questionnaires, namely the MedTech20 (patients' experience of the medic

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Purpose: An increasing body of evidence suggests that excreting a generous volume of diluted urine is associated with short- and long-term beneficial health effects, especially for kidney and metabolic function. However, water intake and hydration remain under-investigated and optimal hydration is poorly and inconsistently defined. This review tests the hypothesis that optimal chronic water intake

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The serum metabolome contains a plethora of biomarkers and causative agents of various diseases, some of which are endogenously produced and some that have been taken up from the environment1. The origins of specific compounds are known, including metabolites that are highly heritable2,3, or those that are influenced by the gut microbiome4, by lifestyle choices such as smoking5, or by diet6. Howev

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Lyme arthritis (LA) is a recognized manifestation of Lyme borreliosis in Sweden, but data on the causative Borrelia species are limited. This study aimed to describe the demographics of LA and identify Borrelia burgdorferi sensu lato (B. burgdorferi s.l.) genospecies present in synovial fluid (SF). Patient data were collected from the test requisition form accompanying consecutive SF samples submi

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Heat pumps are a key technology for decarbonizing residential heating, yet their diffusion remains limited in many countries, partly due to challenges of public acceptance and legitimacy. This study tracks how heat pumps are portrayed in German public discourse by analyzing sentiment in online news coverage. We compile a corpus of 33,131 German heat pump–related news articles published between 201

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In order to reduce its environmental impact, the chemical industry no longer produces base chemicals such as ethylene, solely from fossil, but also from biomass-based feedstocks. However, a biomass option suitable for one region might not be as suitable for another region due to, e.g., long transport and the related environmental. Therefore, local biomass alternatives and the environmental impact

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The recent experimental data on Coulomb breakup of the nucleus Ne-31 are interpreted in terms of deformation. The measured large one-neutron removal cross section indicates that the ground state of Ne-31 is either an s halo or a p halo. The data can be most easily interpreted as the spin of the ground state being 3/2(-) coming from either the Nilsson level [330 1/2] or the Nilsson level [321 3/2]

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INTRODUCTION: A higher prevalence of individuals affected by Parkinsonism was found in Valcamonica, Italy. This may be related to ferro-alloy smelters in the area, releasing manganese (Mn) in the air, soil and water for about a century. There exists individual susceptibility for Mn neurotoxicity. AIM: To analyse how polymorphism in genes regulating Mn metabolism and toxicity can modify neurophysio

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The interaction mechanism of a novel amphiphilic antimicrobial peptide dendrimer, BALY, with model lipid bilayers was explored through a combination of neutron reflection and molecular dynamics simulations. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1,2-dipalmitoyl-sn-glycero-3-phos-phocholine (DPPC) lipid bilayers were examined at room temperature to extract information on the in

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Background: Arthroscopic partial meniscectomy has been shown to be of no benefit to patients with concomitant knee osteoarthritis, but the optimal treatment of a degenerative meniscus tear in patients with mild or no knee osteoarthritis is unknown. This article describes the rationale and methodology of a randomized sham-controlled trial to assess the benefit of arthroscopic partial meniscectomy o

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Apolipoprotein A-I (apoA-I) is the main protein of high-density lipoprotein (HDL) and a principal mediator of the reverse cholesterol transfer pathway. Variants of apoA-I have been shown to be associated with hereditary amyloidosis. We previously characterized the G26R and L178H variants that both possess decreased stability and increased fibril formation propensity. Here we investigate the Milano