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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193297 hits

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Recent decades have exposed the crisis inherent in the globalized agriculture system characterized by nature commodification, trade liberalization, corporatization and environmental destruction. The crisis is driven by a colonial and neoliberal-capitalist ideology grounded in the supposed universality of western knowledge. Smallholders are particularly affected, with the dominant system threatenin

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By applying a critical understanding of empowerment, this study explores the power relations in women’s daily lives through their experience with a mentorship program called Carpe Sophia and analyzes whether or to what extent this program has an impact on women’s empowerment that can bring about gender equality. Carpe Sophia is a women’s economic empowerment program with an aim to increase employm

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Airlines face significant challenges when it comes to sustainability. Globally, the airline industry is responsible for 2% of global emissions and, unfortunately, this number is only increasing (Air New Zealand, 2018). This makes aviation a key actor when attempting to meet the targets published by the IPCC of keeping the global average temperatures below 2°C of pre-industrial levels (IPCC, 2014).

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The purpose of this study is to examine types of challenges during the implementation of BPM regarding the set and use of performance indicators from a theoretical and practical perspective. Consequently, this thesis generates an understanding by illuminating reasons behind the previously found challenges. Hereby, this case study has followed a qualitative, abductive research strategy. The used pr

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Purpose: The purpose of this study is to understand what effects Perceived Brand Identity Fit of luxury fashion collaborations have on Brand Loyalty and ultimately Purchase Intention. Furthermore, Consumer-Brand Identification with the luxury brand is tested as a moderator towards these relationships. Main research question: What is the relationship between unconventional luxury fashion collabora

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Purpose: More than 70% of patients with breast cancer present with node-negative disease, yet all undergo surgical axillary staging. We aimed to define predictors of nodal metastasis using clinicopathological characteristics (CLINICAL), gene expression data (GEX), and mixed features (MIXED) and to identify patients at low risk of metastasis who might be spared sentinel lymph node biopsy (SLNB).Exp

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Background The impact of baseline anemia in a contemporary acute coronary syndrome (ACS) population undergoing percutaneous coronary intervention in the era of predominant radial artery access, potent P2Y12 inhibition, and rare use of glycoprotein IIb/IIIa inhibitors has not been adequately studied. Methods and Results ACS patients who underwent percutaneous coronary intervention between 2014 and

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Background: Laccases are multicopper oxidases, which are assigned into auxiliary activity family 1 (AA1) in the CAZy database. These enzymes, catalyzing the oxidation of phenolic and nonphenolic substrates coupled to reduction of O2 to H2O, are increasingly attractive as eco-friendly oxidation biocatalysts. Basidiomycota laccases are well characterized due to their potential in de-lignification of

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Decomposition of soil organic matter (SOM) may either increase or decrease after fresh organic inputs, the phenomena which are termed as “priming effect”. Crop residues and labile C additions can prime SOM decomposition, but it is not known how labile C inputs affect SOM in the presence of decaying plant residues varying in quality (e.g. from previous crops, a common situation in arable soils). We

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Traumatic brain injury (TBI) contributes to almost one third of all trauma-related deaths, and those that survive often suffer from long-term physical and cognitive deficits. Ciclosporin (cyclosporine, cyclosporin A) has shown promising neuroprotective properties in pre-clinical TBI models. The Copenhagen Head Injury Ciclosporin (CHIC) study was initiated to establish the safety profile and pharma

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Introduction Given that in developed countries we spend about 65% of our time in private homes (Brasche et al. 2005), understanding the exposures in homes is of outmost importance. Airborne particle concentrations indoors can be affected by particles of indoor and outdoor origins, as well as physico-chemical processes indoors, outdoor infiltration affected by tightness of the building envelope and

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Little is known about the association of diet with risk of bladder cancer. This might be due to the fact that the majority of studies have focused on single food items, rather than dietary patterns, which may better capture any influence of diet on bladder cancer risk. We aimed to investigate the association between a measure of Western dietary pattern and bladder cancer risk. Associations between

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Agricultural land use is a major driver of biodiversity losses and changes in ecosystem services. Thus, for the sake of both humans and wild organism per se, effective strategies that enable both agricultural production and conservation of biodiversity and ecosystem services are urgently needed. Such strategies can be divided into those that reduce the intensity of farming in general (such as orga

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Studies investigating risk factors associated with atrial fibrillation (AF) have mostly focused on AF presence and burden, disregarding the temporal distribution of AF episodes although such information can be relevant. In the present study, the alternating, bivariate Hawkes model was used to characterize paroxysmal AF episode patterns. Two parameters: the intensity ratio µ, describing the dominat

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In recent years several aids for automated interpretation of visual field data have been suggested. We believed that incorporation of thorough knowledge of normal visual field variability would allow improvements in the performance of such aids since more attention would be paid to field results in areas with low physiological variability. Two visual field models for classification of fields in gl

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One important step in binary modeling of environmental problems is the generation of absence-datasets that are traditionally generated by random sampling and can undermine the quality of outputs. To solve this problem, this study develops the Absence Point Generation (APG) toolbox which is a Python-based ArcGIS toolbox for automated construction of absence-datasets for geospatial studies. The APG

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Improving urban liveability and prosperity is commonly set as a priority in urban development plans and policy around the world. Several annual reports produced by international consulting firms, media, and global agencies rank the liveability of cities based on a set of indicators, to represent the quality of life in these cities. The higher is the ranking, the more liveable is the city. In this