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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 194524 hits

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Background: The workplace setting is a prioritized arena for health promotion to battle non-communicable diseases. App-based interventions have shown promise to be useful tools for workplace-based health promotion. However, the effects of app-based interventions have been found to be moderate. The aim of this study is to construct a conceptual model explaining how a health promotion app, that is i

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Purpose The purpose of this research paper is to investigate the phenomenon of destructive entrepreneurship from a contextual perspective, by conducting a narrative study in a cosmopolitan city of Sweden. A narrative story is constructed based on the life story of a drug dealer. This narrative is used as input in interviews with respondents representing different political and social organisations

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Zambezi River Basin is an international river basin which sustains life of about 30 million people in its riparian countries: Angola, Botswana, Malawi, Mozambique, Namibia, Tanzania, Zambia and Zimbabwe. The main stream of the river enters to Mozambique with average flow of about 2330 m3/s and reaches the outfall in the Indian Ocean with about 4134 m3/s. This makes both the activities in the upstr

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Hepatocellular carcinoma (HCC), commonly diagnosed at an advanced stage, is the most common primary liver cancer. Owing to a lack of effective HCC treatments and the commonly acquired chemoresistance, novel therapies need to be investigated. Cyclophilins—intracellular proteins with peptidyl-prolyl isomerase activity—have been shown to play a key role in therapy resistance and cell proliferation. H

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Objective: To compare the concentrations of high mobility group box 1 protein (HMGB1) and S100A8/A9 in synovial fluid between patients with knee injuries and osteoarthritis (OA), and knee healthy subjects. To investigate associations of alarmin levels with different joint injuries and with biomarkers of inflammation, Wnt signaling, complement system, bone and cartilage degradation. Methods: HMGB1

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While Western imperialism played a crucial role in the creation of modern international law, it is ever more important to analyze the engagements of non-Western imperialist powers with the field so as to comprehend the changing global patterns of legalized violence and expansionism. In this Essay, we analyze Russia's international legal arguments in support of its use of force against Ukraine thro

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BACKGROUND: The relationship between coping in mid- to late life and cognitive functions remains unclear. OBJECTIVE: To investigate the relationship between habitual coping behaviors of a large Japanese population in their mid- to late-lives and their risk of cognitive decline 15 years later. METHODS: Overall 1,299 participants were assessed for coping behaviors (in 2000) and cognition (2014-2015)

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The consolidation of a global anticorruption regime can be seen has a combination of international policy instruments, ideologies about good and bad governance, and a whole set of promises, programmes and practices all intended to reduce corruption. After nearly two decades, we can give this assemblage a name: Anticorruptionism. This paper reviews the history of anticorruptionism and the current s

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In the recent years, large progresses in laser imaging techniques have allowed to extract spatially resolved 2D and 3D quantitative spray information even in optically dense situations. The main breakthrough of these techniques is the possibility of suppressing unwanted effects from multiple light scattering using Structured Illumination. Thanks to this new feature, effects due to light extinction

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The infrared spectrum of water, isolated in inert matrices, has been studied in the interval from 60 to 4000 cm(-1). Experiments with partially deuterated water combined with DFT (density functional theory) calculations have been used to investigate the structure of matrix-isolated water tetramer. A few, strong intermolecular fundamentals of the water tetramer have been observed. Mid-infrared band

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While the risk of ovarian cancer clearly reduces with each full-term pregnancy, the effect of incomplete pregnancies is unclear. We investigated whether incomplete pregnancies (miscarriages and induced abortions) are associated with risk of epithelial ovarian cancer. This observational study was carried out in female participants of the European Prospective Investigation into Cancer and Nutrition

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Populärvetenskaplig sammanfattning: De skånska bokskogarna. Vad kan krypen säga? Det är mycket som påverkar våra skogar i dag. Vägar som delar upp dem i mindre delar och lantbruk och kvävenedfall som stör balansen för vad som ska växa i skogens utkanter med sin gödsling. Även trafiken påverkar genom att kväveoxiderna i avgaserna har en gödande effekt. Skogens hälsa påverkas självklart av detta, Abstract Deforestation, fragmentation and loss of biodiversity, all are elements that are common today. With this project I want to evaluate if there is a difference in functional diversity of evertebrates between beech stands of low herb and shrub type beech forest. I also want to test if there is a difference within tested areas between low herb and shrub type forests, but also if here is a dif

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This paper examines the freedom of expression in a newly established in Eastern Europe democracy, namely in Azerbaijan. Before reviewing the domestic law of Azerbaijan on freedom of expression, the study touches upon a few important thoughts and statements about the interdependence of freedom of expression and democracy. Afterwards it elaborates international binding as well as non-binding standar

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Breast cancer is one of the most common cancers in the world, and has therefore been widely researched the last decades. Breast cancer is one of the least aggressive cancer types, and this together with extensive research has given one of the highest survival rate of any cancer types. However, there is still a long way to go in order to decrease the number of deaths even further. New, more effecti

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In archaeology, we face a unique situation where our primary research method is destructive; excavation as a recording method can only be conducted once. But with the introduction of modern 3D recording methods, much of the process of excavation can be saved and reused. But at the same time, we must overcome the difficulties of examining sites where the data recorded has been accumulated over vast

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Pancreatic cancer represents three percent of all incident cancer cases in developed countries, but stands the 7th most common cause of cancer related death. Worldwide, pancreatic cancer is more common among men, however in Sweden, the incidence ratio between sexes is levelling. Despite extensive research to map underlying risk factors, results are still largely inconclusive. Furthermore, there is