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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192247 hits

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We have performed investigations to see if the emergent macrophyte Phragmites australis (Cav.) Trin. ex Steud. exhibits phenotypic plasticity as a response to water depth and if such responses in biomass allocation pattern and morphology are functional responses, improving the performance of the plant. In greenhouse experiments plants were grown in deep or shallow water to evaluate plastic respons

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Background: The maintenance of postural control is fundamental for different types of physical activity. This can be measured by having subjects stand on one leg on a force plate. Many studies assessing standing balance have previously been carried out in patients with ankle ligament injuries but not in patients with ankle fractures. The aim of this study was to evaluate whether patients operated

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Abstract in UndeterminedThe indigenous psychologies (mostly, Non-Western approaches to scientific research in psychology) occur in different varieties but they all aim to be culturally and pragmatically relevant to the researcher’s own society. In these psychologies Western mainstream psychology has been argued to be too affected by liberal, individualistic and secular values. Some examples of suc

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Purpose: To illustrate that the attenuation formula based on monochromatic radiation in homogeneous objects may be used for dose regulation in body computed tomography (CT) based on patient circumference and using a simple cloth measuring tape. Material and Methods: Based on the attenuation formula for monochromatic radiation, the following Microsoft Excel equation was derived: mAs(x)=mAs(n)* EXP(

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Endoderm development is an area of intense interest in developmental biology, but progress has been hampered by the lack of specific markers for differentiated endodermal cells. In an unbiased secretion cloning screen of Xenopus gastrula embryos we isolated a novel gene, designated Darmin. Darmin encodes a secreted protein of 56 kDa containing a peptidase M20 domain characteristic of the glutamate

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Purpose: To describe the clinical and electrophysiological findings in a young boy with decreased vision possibly due to retinal damage by rifabutin. Methods: An 8-year-old boy with osteomyelitis was referred due to visual disturbance. During a period of 4 years, the boy was examined six times with electroretinography. Ophthalmological examination included testing of visual acuity, slit-lamp inspe

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Popular Abstract in Swedish Länder som strävar efter att kvalificera sig för medlemskap i Europeiska unionen måste genomföra omfattande reformer under kort tid. Som en effekt av anpassningsprocessen till unionens regelverk och politiska, ekonomiska och administrativa kriterier omstruktureras statsapparaten. Detta gäller inte minst i de kandidatländer som samtidigt genomgår radikala transformationsIt is generally recognized that the EU accession process has profound effects on state transformation in the postcommunist applicant countries. A key problem of postcommunism has been a weak ability to implement public policy. This study explores how efforts to fulfill EU conditionality may influence implementing capacity. Firstly, it advances a theoretical framework for this purpose, focusing on

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The leakage characteristics of a novel claw-pole electrically magnetized synchronous machine are discussed in this paper. The novelty of the machine is that the magnetizing coils are placed in magnetically conducting end-plates, thus eliminating the need of slip-rings in the rotor. A previous study comparing this machine with a permanent magnet alternative showed a 20% higher leakage in the electr

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We have previously reported suggestive linkage to chromosome 5p13-q13 in type 1 diabetic families. ISL1, a transcription factor involved in pancreas development, maps to this region. Sequencing of the ISL1 gene in patients and control subjects identified seven single nucleotide polymorphisms (SNPs) and one microsatellite in noncoding regions. Four haplotypes formed by six of these SNPs and one mic

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Aims To describe clinical and demographic characteristics at baseline of a European cohort of adults with congenital heart disease (CHD) and to assess mortality and morbidity in a 5 year follow-up period. Methods and results Data collected as part of the Euro Heart Survey on adult CHD was analysed. This entailed information transcribed from the files of 4110 patients diagnosed with one of eight co

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This study addresses caring staff experiences of hindrances and help in the support of daily occupations among people with developmental disabilities. Data were collected by means of a questionnaire consisting of open-ended questions about the staff perceptions of their work experiences. The respondents (n = 81), corresponding to 94.1% of all care staff employed in a geographically defined care ar

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Once activated, some T cells home to distinct sites in the body, such as the intestine and inflamed skin. Research in mice shows that dendritic cells in the gut produce a derivative of vitamin A, retinoic acid, that gives T cells directions.

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We propose an event-based account of the cognitive and linguistic representation of time and temporal relations. Human beings differ from nonhuman animals in entertaining and communicating elaborate detached (as opposed to cued) event representations and temporal relational schemas. We distinguish deictically based (D-time) from sequentially based (S-time) representations, identifying these with t

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Background: beta-Amyloid (A beta) plaques are a pathological hallmark of Alzheimer's disease (AD) and multiple lines of evidence have linked A beta with AD. However, synapse loss is known as the best pathological correlate of cognitive impairment in AD, and intraneuronal A beta accumulation has been shown to precede plaque pathology. The progression of A beta accumulation to synapse loss and plaqu

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BACKGROUND: Growth differentiation factor 15 (GDF15) belongs to the transforming growth factor beta superfamily and has been associated with activation of the p53 pathway in human cancer. The aim of this study was to assess the prognostic value of GDF15 in patients with colorectal cancer (CRC). METHODS: Immunohistochemistry and tissue microarrays were used to analyse GDF15 protein expression in 32

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Background The rate of uptake of volatile anesthetics is dependent on alveolar concentration and ventilation, blood solubility and cardiac output. We wanted to determine whether increased tidal volume (V-T), with unchanged end-tidal carbon dioxide partial pressure (PETCO2), could affect the arterial concentration of sevoflurane. Methods Prospective, randomized, clinical study. ASA physical status

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Background: Several studies have examined leukocyte telomere length (LTL) as a possible predictor for cancer at various organ sites. The hypothesis originally motivating many of these studies was that shorter telomeres would be associated with an increase in cancer risk, the results of epidemiologic studies have been inconsistent, however, and suggested positive, negative, or null associations. Tw

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Orthogonal P-wave morphology has previously been described in different populations, but its relation to atrial size has not been studied in detail. In this study, we investigated whether atrial size affects P-wave morphology in athletes, who are known to have different degrees of atrial enlargement.