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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193064 hits

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The recent past has witnessed a rising interest in examining the cultural, economic, and social implications of colonialism and especially of trans-Atlantic slavery. As a result, many academic institutions have been sanctioning research projects to ascertain their own and certain historical figures’ roles in trans-Atlantic slavery. Whilst the research undertaken is very pertinent in understanding

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The first mass-distributed vaccines based on mRNA technology were launched in 2021 to protect against COVID-19, sparking rumours among vaccine critical individuals that these “new” vaccines might be more dangerous to the health than other, “traditional” vaccines. Drawing on rumour theories and social cognitive perspectives, the aim of this chapter is to account for the purpose and the spreading of

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Vaccine hesitancy is considered as one of the greatest challenges to control the ongoing coronavirus disease 2019 (COVID-19) pandemic. A related challenge is the unwillingness of the general public to pay for vaccination. The objective of this study was to determine willingness-to-pay (WTP) for COVID-19 vaccine among individuals from ten low-middle-income countries (LMICs) in Asia, Africa, and Sou

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The first mass-distributed vaccines based on mRNA technology were launched in 2021 to protect against COVID-19, sparking rumours among vaccine critical individuals that these “new” vaccines might be more dangerous to the health than other, “traditional” vaccines. Drawing on rumour theories and social cognitive perspectives, the aim of this chapter is to account for the purpose and the spreading of

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Depositional practices have been regarded as a part of a Neolithic lifestyle together with farming and keeping livestock. As an ongoing discussion shows, however, it is not entirely clear how we should understand these practices. The categorization of Neolithic pits still raises questions and leaves some issues unresolved, especially as the categorization often leads to the use of dichotomies, and

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Numerous assays exist to measure aggressive behaviour in honeybees, most of them using free-flying bees under natural conditions, with results often variable due to environmental factors. Our study describes a novel, laboratory-based Petri dish assay that uses a moving target treated with the alarm pheromone component isoamyl acetate (IAA). In this assay, aggression levels can be measured in indiv

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Scale invariance and self-similarity in physics provide a unified framework for classifying phases of matter and dynamical properties near equilibrium in both classical and quantum systems. This paradigm has been further extended to isolated many-body quantum systems driven far from equilibrium, for which the physical observables exhibit dynamical scaling with universal scaling exponents. Universa

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We report energy renormalizations from electron-phonon and electron-magnon interactions in spin minority surface resonances on Ni(111). The different interactions are identified, disentangled, and quantified from the characteristic signatures they provide to the complex self-energy and the largely different binding energies at which they occur. The observed electron-magnon interactions exhibit a s

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The diverse gut microbiota, which is associated with mucosal health and general wellbeing, maintains gut-associated lymphoid tissues (GALT) in a chronically activated state, including sustainment of germinal centers in a context of high antigenic load. This influences the rules for B cell engagement with antigen and the potential consequences. Recent data have highlighted differences between GALT

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Children and adolescents exposed to traumatic events are at high risk of developing posttraumatic stress disorder (PTSD). With the rare exception of very young children, their PTSD presentations at the symptom level are similar to those of trauma-exposed adults, as are their patterns of psychiatric comorbidity, particularly for adolescents. Untreated, at least a significant proportion will carry o

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We present a detailed investigation into a source of distortion that affects the classic bootstrapped switch. Our analysis reveals that the transition phase between track mode and hold mode is a critical factor in causing the distortion. To address this issue, we propose a novel technique that effectively mitigates the problem. Our results, based on simulations conducted using a 22-nm FDSOI CMOS p

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In a seminar room at LUX, one of the buildings of the Joint Faculties of Humanities and Theology, a group of PhD students and senior scholars are in deep concentration in front of their computers. It is pin-drop silent in the room until the alarm goes off and everyone starts moving and talking. This is the writing group, an informal and voluntary way of working together in

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CP4 3HDM is a three-Higgs-doublet model based on the CP symmetry of order 4 (CP4). Imposing CP4 leads to remarkable connections between the scalar and Yukawa sectors and unavoidably generates tree-level flavor-changing neutral couplings (FCNC). It remains unclear whether FCNC can be sufficiently suppressed in the CP4 3HDM. In this paper, we systematically explore this issue. We first develop an ef

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Background: Selection pressure exerted by pathogens can influence patterns of genetic diversity in the host. In the immune system especially, numerous genes encode proteins involved in antagonistic interactions with pathogens, paving the way for coevolution that results in increased genetic diversity as a consequence of balancing selection. The complement system is a key component of innate immuni

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Forced cross-border migration and entrepreneurship have persisted as perennial themes throughout the annals of human history. However, the recent ‘refugee crisis’ has sparked a resurgence of interest in their interplay under the rubric of ‘refugee entrepreneurship’. While its territory is not entirely uncharted, a surge in scholarly urgency and heightened scientific production have significantly e