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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192326 hits

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Bakgrund Teknikutvecklingen inom hälso- och sjukvårdsområdet möjliggör ständigt nya och mer avancerade sätt att distansmonitorera och vårda patienter digitalt. Digitaliseringen inom hälso- och sjukvårdsområdet i form av till exempel hälsoapplikationer gör det möjligt för patienter och personal att ha kontakt och kommunicera digitalt med varandra (WHO, 2011). itACiH är ett digitalt system där patie

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Novelty is a core value in science, and a reliable measurement of novelty is crucial. This study proposes a new approach of measuring the novelty of scientific articles based on both citation data and text data. The proposed approach considers an article to be novel if it cites a combination of semantically distant references. To this end, we first assign a word embedding–a vector representation o

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A Large Intelligent Surface (LIS) is a recently pro-posed concept that relies on the integration of a vast number of antenna-elements over an entire surface able to transmit and/or receive information, especially suitable for high speed indoor communications and massive internet of things (IoT) applications. In this paper, we study the impact of terminal mobility on the performance of a panel-base

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Introduction/Aim of the Study. One way of investigating health trends at the population level is to study the physical performance and functional ability in different birth cohorts. The information obtained can be used to predict illness, disability, and future needs for care. However, contradictory findings have been reported when comparing the physical performance of older adult birth cohorts. T

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Land use is at the core of today’s complex sustainability challenges. Agricultural and environmental economics share a focus land and resource use but evolved in their own domains. Their specialized competencies can be complementary and thus strengthen policy analysis. We use structural topic modelling on more than 24,000 articles in the top agricultural economics and environmental economics journ

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Introduction: Antimicrobial resistance (AMR) is a global public health threat. Worse still, there is a paucity of data from low-and middle-income countries to inform rational antibiotic use. Objective: Assess the feasibility of setting up microbiology capacity for AMR testing and estimate the cost of setting up microbiology testing capacity at rural district hospitals in Rwanda. Methods: Laborator

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This chapter considers the Norwegian verb rekke ('reach') and its English correspondences in a bi-directional translation corpus (ENPC), as well as occurrences of rekke in Norwegian monolingual corpora. We suggest that rekke is undergoing grammaticalization from a concrete lexical spatial verb towards a (semi-)auxiliary that contains a component of time sufficiency, similar to Swedish hinna (Johan

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OBJECTIVES: From a reproductive justice framework, we aimed to investigate how a possible association between hormonal contraceptive (HC) and antidepressants use (as a proxy for depression) is distributed across intersectional strata in the population. We aimed to visualise how intersecting power dynamics may operate in combination with HC use to increase or decrease subsequent use of antidepressa

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Tumor necrosis factor (TNF) possesses both beneficial and toxic bioactivities. Mechanisms may operate to counteract harmful effects. We have identified a TNF binding protein (TNF-BP), which shows increased levels in serum and urine of patients on regular hemodialysis treatment (RDT). TNF-BP inhibited the specific binding of human recombinant TNF (rTNF) to its cell surface receptor. Results from ge

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Background: The modern style of goalkeeping in ice hockey is thought to predispose athletes to hip and groin problems. However, little is known about the magnitude of these problems in elite goalkeepers.Purpose: To describe the incidence, prevalence, and severity of hip and groin problems in elite ice hockey goalkeepers over the course of a single season.Study Design: Descriptive epidemiology stud

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Neuroblastoma is a childhood solid tumour originating from undifferentiated neural progenitor cells of the sympathetic nervous system. Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. In the present study, we aimed to identify novel drugs that can inhibit the growth and survival of chemoresistant neuroblastoma. High-throughput screening identified a small molecule,

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The Jewel of Annual Astrology is an encyclopaedic treatise on Tājika or Sanskritized Perso-Arabic astrology, dealing particularly with the casting and interpretation of anniversary horoscopes. Authored in 1649 CE by Balabhadra Daivajña, court astrologer to Shāh Shujāʿ – governor of Bengal and second son of the Mughal emperor Shāh Jahān – it casts light on the historical development of the Tājika s

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This paper presents a critical literature review of academic articles that analyze the role of formal and informal institutions in entrepreneurial ecosystems. It discusses which types of formal and informal institutions matter for the development of ecosystems, highlighting the importance of considering the specific type of legal system of the country in which they develop, i.e. its legal origin (

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The most common, severe cases of fetal and neonatal alloimmune thrombocytopenia among whites are caused by antibodies against human platelet antigen 1a (HPA-1a). The aims of this systematic review and meta-analysis are to determine the association between maternal HLA-DRB3∗01:01 and: (1) HPA-1a-alloimmunization and (2) neonatal outcome in children born of HPA-1a-immunized women. A systematic liter

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Grancalcin is a newly discovered cytosolic calcium-binding protein, belonging to the group of EF-hand proteins. Grancalcin is specifically associated with cells originating in the bone marrow. Grancalcin binds reversibly to secretory vesicles and plasma membranes in human neutrophils and might therefore play a role in the regulation of vesicle/granule exocytosis. We describe here the production of

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Purpose: To assess the performance of a 4-step algorithm for neurological prognostication after cardiac arrest recommended by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM). Methods: Retrospective descriptive analysis with data from the Target Temperature Management (TTM) Trial. Associations between predicted and actual neurological outcome wer

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Endwall film cooling upstream of the leading edge (LE) of a vane presents a relatively complex flow phenomenon due to the horseshoe vortices (HVs) generated at the LE region. Upstream of the LE region, the coolant flow has difficulties to eject out. This research work focuses on controlling the jet holes coolant coverage upstream of the LE region. Compound angle holes in staggered arrangement are

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Little is known about the impacts of persistent triazine herbicides and biocides on soil microorganisms. Terbutryn toxicity in soil microorganisms was studied using bacterial and fungal growth, substrate induced respiration (SIR) and basal respiration as ecotoxicological end-points. In the short-term (0–7 days), increasing concentrations of terbutryn (0–800 mg kg−1) progressively inhibited bacteri

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Over the past years, interest in classifying drivers' behavior from data has surged. Such interest is particularly relevant for car insurance companies who, due to privacy constraints, often only have access to data from Inertial Measurement Units (IMU) or similar. In this paper, we present a semi-supervised learning solution to classify portions of trips according to whether drivers are driving a