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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193072 hits

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Analysing the historiography of early to mid 20th century monumental painting in Sweden, the article argue that this historiography is characterised by a recurring interest of unactualised avant-garde proposals for public art (many of them preserved as sketches at Skissernas Museum – Museum of Artistic Process and Public Art in Lund). Sketches for these proposals are set forward as key monuments i

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Both research and policy recognize land systems as fundamental to human life and activities. However, these two perspectives approach land from different ends and it can be difficult to see how studied variables contribute to broader policy goals. In this paper, we argue that there is a need to better select variables to study land systems as social-ecological systems, and to align research more w

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OBJECTIVE: The Diabetes Prevention Program (DPP) trial investigated rates of progression to diabetes among adults with prediabetes randomized to treatment with placebo, metformin, or intensive lifestyle intervention. Among women in the DPP, diabetes risk reduction with metformin was greater in women with prior gestational diabetes mellitus (GDM) compared with women without GDM but with one or more

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Background: The industrially important yeast Blastobotrys (Arxula) adeninivorans is an asexual hemiascomycete phylogenetically very distant from Saccharomyces cerevisiae. Its unusual metabolic flexibility allows it to use a wide range of carbon and nitrogen sources, while being thermotolerant, xerotolerant and osmotolerant. Results: The sequencing of strain LS3 revealed that the nuclear genome of

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Single-chain variable fragments (scFv) are widely used in several fields. However, they can be challenging to purify unless using expensive Protein L-based affinity adsorbents or affinity tags. In this work, a purification process for a scFv using mixed-mode (MM) chromatography was developed by design of experiments (DoE) and proteomics for host cell protein (HCP) quantification. Capture of scFv f

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Uttered Expectations was a reading event performed 27 June 2013, as part of a PhD project at the Department of Architecture, Lund University. Within the frame of the PhD project a series of research interventions were pursued about the establishing of a large-scale science park in an agrarian area just outside the city of Lund, Sweden. In Uttered Expectations written comments from participants tha

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Genetic studies promise to provide insight into the molecular mechanisms underlying type 2 diabetes (T2D). Variants associated with T2D are often located in tissue-specific enhancer clusters or super-enhancers. So far, such domains have been defined through clustering of enhancers in linear genome maps rather than in three-dimensional (3D) space. Furthermore, their target genes are often unknown.

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Context. The dynamics of a low-mass protoplanet accreting solids is influenced by the heating torque, which was found to suppress inward migration in protoplanetary disks with constant opacities. Aims. We investigate the differences in the heating torque between disks with constant and temperature-dependent opacities. Methods. Interactions of a super-Earth-sized protoplanet with the gas disk are e

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An area of considerable interest in second language (L2) acquisition is the difficulties learners face with the acquisition of articles. This article examines the role of prosody in the acquisition of articles by an endstate L2 English speaker focusing on the free morphemes the and a. In order to analyse the articles produced by a Turkish speaker named SD, we used the Praat (Boersma and Weenink, 2

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Non-compliance with food record submission can induce bias in nutritional epidemiological analysis and make it difficult to draw inference from study findings. We examined the impact of demographic, lifestyle and psychosocial factors on such non-compliance during the first 3 years of participation in a multidisciplinary prospective paediatric study.

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OBJECTIVE.: Finding of venous congestion at histopathological examination of placenta indicates the importance of abnormal placenta-maternal venous return. The present descriptive study investigates the possibility of recording Doppler flow signals from maternal uterine veins. MATERIAL AND METHODS.: Transabdominal Doppler ultrasound examinations of uterine veins on both sides of uterus were perfor

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The production of municipal solid waste is one central concern for environmental policy, and the socio-materiality of waste – how the organisation of waste streams affects households and other waste producers – is an important issue for sustainability. This article shows how the application of European Union waste policy through its waste hierarchy affects the socio-material status of waste. The w

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Inflammation is a well-established risk factor for the development of coronary artery disease (CAD) and acute coronary syndrome (ACS). However, less is known about its influence on the outcome of ACS. The aim of this study was to determine if blood biomarkers of inflammation were associated specifically with acute myocardial infarction (MI) or unstable angina (UA) in patients with ACS.

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Many small enterprises that are planning to implement environmental management systems (EMSs) and get certified according to the ISO 14001 standard or EMAS regulation have experienced a lot of barriers on the road towards certification. The standards are perceived as bureaucratic and represent a way of working that often fits poorly into the organizational culture and decision-making structure of