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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192355 hits

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Apolipoprotein A-I (ApoA-I) is the major protein constituent of high-density lipoprotein particles, and as such is involved in cholesterol transport and activation of LCAT (the lecithin:cholesterol acyltransferase). It may also form amyloidal deposits in the body, showing the multifaceted interactions of ApoA-I. In order to facilitate the study of ApoA-I in various systems, we have developed a pro

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Objective: Abdominal aortic graft and endograft infection (AGI) is primarily treated by resection of the infected graft and restoration of distal perfusion through extra-anatomic bypass (EAB) or in situ reconstruction/repair (ISR). The aim of this study was to compare these surgical strategies in a nationwide multicentre retrospective cohort study. Methods: The Swedish Vascular Registry (Swedvasc)

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Background: Most studies infer increasing incidence of proximal humeral fractures (PHF) from the 1950´s until the 1990´s. Recent time trends are less clear. Objectives: Our primary objective was to identify time trends in the age- and sex-adjusted adult incidence of PHF in Malmö, Sweden, from year 1944 until 2020. Our secondary objectives were to describe the variation in incidence according to ag

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The aim of this prospective, international multicenter, pseudorandomized study comparing RICT HCT to standard-of-care chemotherapy in intermediate- or high-risk AML patients 50–70 years using the donor versus no-donor concept. Part 1 included only patients with potential family donors (RD) at the date of HLA-typing of the first potential sibling or CR-date, if later. Part 2 allowed the inclusion o

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Background: Osteonecrosis (ON) is a potentially disabling skeletal complication of cancer treatment. Although symptomatic osteonecrosis (sON) is well-known in acute lymphoblastic leukemia (ALL), with an incidence around 6%, studies on sON in pediatric Hodgkin lymphoma (HL) are scarce. The aim of this study was to examine the incidence, risk factors, and outcome of sON in children treated for HL. P

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Starting from a single layer of NbS2 grown on graphene by molecular beam epitaxy, the single unit cell thick 2D materials Nb5/3S3-2D and Nb2S3-2D are created using two different pathways. Either annealing under sulfur-deficient conditions at progressively higher temperatures or deposition of increasing amounts of Nb at elevated temperature result in phase-pure Nb5/3S3-2D followed by Nb2S3-2D. The

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This report contributes to the research project FIRE21 (Fire and Rescue Services in the 21st Century) and is part of a work package looking into key individual qualities for efficient collective problem-solving in a fire and rescue service (FRS) context.

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Background: Seasonal allergic rhinitis (AR) impacts public health by affecting work productivity and quality of life. The Swedish tree pollen season starts in February with alder and hazel pollination, followed by birch and ends with oak in May. Systemic corticosteroids are often prescribed when topical treatments fail, despite limited evidence supporting their efficacy. Objective: To compare the

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As rapid urbanization intensified pressure on coastal ecosystems, balancing economic development with ecological preservation remained a critical challenge. This study developed a multi-criteria framework for integrated marine spatial planning and applied it to Shenzhen, China—a rapidly expanding coastal metropolis overseeing 1145 km2 of marine territory with a 260.5 km coastline, 61.47% of which

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Oily wastewater presents a serious environmental challenge, demanding sustainable and regenerative membrane technologies. Here, we report a green and scalable method for fabricating skin-replaceable cellulose membranes (SRC-M) from jute agro-waste, using a NaOH/urea activation route and argon-pressurized deposition onto ceramic supports. The resulting Cellulose II-based asymmetric membranes exhibi

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This book provides a critique of David Harvey's theory of land rent and his replacement of Marx's concept of absolute rent with class-monopoly rent, arguing that this shift inadequately addresses crucial theoretical and empirical problems in urban economic geography today. The alternative introduced links land rent to fluctuations in profit rates rather than monopoly pricing. Land Rent, Capital, R

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ObjectivePediatric cancer patients are at increased risk for sleep disturbances; however, there are no clinical practice guidelines for treating sleep disturbances in pediatric oncology, resulting in variable approaches to sleep management across clinicians. The current study surveyed clinicians regarding their approaches to assessing and treating sleep.MethodsA total of 200 pediatric oncology cli

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In multiple-planet systems, gravitational interactions of exoplanets could lead to transit timing variations (TTVs), whose amplitude becomes significantly enhanced when planets are in or near mean-motion resonances (MMRs), making them more easily detectable. In cases where both TTVs and radial velocity (RV) measurements are available, combined analysis can break degeneracies and provide robust pla

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Like many other West African countries, The Gambia faces challenges regarding discrimination based on descent, which relates to the inherited disadvantage of being born into a specific group (RADDHO & IDSN, 2012). This sociological case study has the analytical purpose of discussing the case of social stratification and descent-based discrimination in the Fulani village of Nokuta in The Gambia

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Escherichia coli O157:H7 is a non-invasive Shiga toxin (Stx)-producing pathogen that causes gastroenteritis and hemolytic uremic syndrome characterized by acute kidney injury. Stx binding to cells induces release of extracellular vesicles (EVs) containing the toxin. This study aimed to demonstrate the lethal effects of toxin-positive vesicles, and the importance of the Stx receptor, globotriaosylc

Efter stroke – fokus på mobilitet utanför hemmet – Vetenskap och Hälsa

Efter stroke – fokus på mobilitet utanför hemmet – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Efter stroke – fokus på mobilitet utanför hemmet 2019-03-18 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Foto: Wikimedia Commons Efter str

https://www.vetenskaphalsa.se/efter-stroke-fokus-pa-mobilitet-utanfor-hemmet/ - 2026-07-19

Erik Berntorp: Blödarsjuka – på väg mot bot – Vetenskap och Hälsa

Erik Berntorp: Blödarsjuka – på väg mot bot – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Erik Berntorp: Blödarsjuka – på väg mot bot 2012-09-17 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Illustration: Colourbox Min forskning är in

https://www.vetenskaphalsa.se/erik-berntorp-blodarsjuka-pa-vag-mot-bot/ - 2026-07-19

Nu klarnar bilden av celler och gener i de diabetiska öarna – Vetenskap och Hälsa

Nu klarnar bilden av celler och gener i de diabetiska öarna – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Nu klarnar bilden av celler och gener i de diabetiska öarna 2017-09-25 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Forskare vi

https://www.vetenskaphalsa.se/nu-klarnar-bilden-av-celler-och-gener-i-de-diabetiska-oarna/ - 2026-07-19