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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193069 hits

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Abstract The glycosaminoglycan dermatan sulfate plays a crucial role in the process of tumorigenesis, due to increased flexibility in the polysaccharide chain, when glucuronic acid, in the glycan chondroitin sulfate, epimerizes into iduronic acid. The conversion facilitates a change in the interaction with certain proteins such as growth factors, angiogenic factors, and cytokines. The enzyme invol

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Spectroscopy serves as a vital tool in both scientific research and industrial applications. In spectral analysis, baseline correction is important in order to be able to efficiently extract essential features. Several algorithms for baseline correction have been developed, including Asls (Asymmetric Least Squares algorithm), arPLS (Asymmetrically Reweighted Penalized Least Squares algorithm), air

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The purpose of this study is to analyse the communication of Apple to illustrate how social exclusion is used to produce fear, and how it has played the role as a means of persuasion in a constructed reality. In the present investigation process the researchers have taken a critical stance. The authors aim at unveiling the structure of implicit means of persuasion in various Apple’s campaigns over

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The variety of different controllers is today very big. Much research is done in the field of neural network control and more well established technologies are sometimes looked at as old fashioned. The work is much based on the identification of a process model. In this report some different controllers have been built to see if neural networks are a good alternative to classic controllers. The cl

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Microalgae have become an increasingly interesting field of research for the production of biofuel and health beneficial lipids such as omega-3. Useful characteristics of the algae are their rapid growth and high levels of lipid accumulation. For growth of microorganisms as biofactories to industrially produce bulk or specialty compounds, economically feasible and energetically efficient feed subs

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Like many other West African countries, The Gambia faces challenges regarding discrimination based on descent, which relates to the inherited disadvantage of being born into a specific group (RADDHO & IDSN, 2012). This sociological case study has the analytical purpose of discussing the case of social stratification and descent-based discrimination in the Fulani village of Nokuta in The Gambia

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Areas experiencing conflict are challenging to examine due to limited accessibility. Remote sensing is a valuable tool that can be used to evaluate the effects of conflict on the environment. Northwestern Syria hosts most of the country’s remaining Mediterranean forests, an ecosystem that is ecologically significant for regulatory ecosystem services. Since 2011, Syria has experienced conflict, whi

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In this thesis I investigate the recent changes in abortion legislation in Colombia (liberalization) and Nicaragua (criminalization). By making a comparative case study I intend to find the factor(s) that could explain the different directions in legislation, given that both countries are of great similarity (location, religion, history, and political culture). The analysis made is based on John K

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A new model-free method is presented that automatically corrects for phase shifts, frequency shifts, and additional lineshape distortions of one single resonance peak across a series of in vivo NMR spectra. All separate phase and frequency variations are quickly and directly derived from the common lineshape in the data set using principal component analysis and linear regression. First, the new a

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Soon after the annexation of Crimea by the Russian Federation in March 2014, a peak moment in the events commonly referred to as the Ukraine crisis (Wilson A, Ukraine crisis. What it means to the West? Yale University Press, New Haven, 2014), media in Estonia and abroad started to speculate about whether Russia would stop at Crimea, or if Estonia, with its sizable Russian-speaking minority, would

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Lessons learned in the feedback process are atwo-sided coin that ultimately guide the PhD candidatetowards becoming an independent researcher as well aseducating “reader/docents” in their role as supervisor.Building on a brief literature review, observations from 14interviewed PhD candidates were reflected upon and these arethe suggested lessons learned. The study’s preliminary findingssuggest tha

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In multiple-planet systems, gravitational interactions of exoplanets could lead to transit timing variations (TTVs), whose amplitude becomes significantly enhanced when planets are in or near mean-motion resonances (MMRs), making them more easily detectable. In cases where both TTVs and radial velocity (RV) measurements are available, combined analysis can break degeneracies and provide robust pla

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This thesis aims to bring a greater understanding of the recent rise in right-wing populism by analysing the authoritarian populist discourse used by Donald Trump when he speaks to his base. In the study, the transcript of his speech at the Minnesota Rally in October 2019 is studied with the method critical discourse psychology. The theoretical framework is a combination of post-structuralism and

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The higher efficiency and higher availability (fault-tolerant oriented) of RF & Cavity system (with beam loading) to operate at, the more dynamic details needs to be identified, so as to have the abilities (a) to work at nonlinearities, (b) to work close to limitation, and (c) to change operation point quickly and correctly. Dynamic detail identifications rely heavily on high precision measuri

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Purpose: Air monitoring has been the accepted exposure assessment of toxic metals from, e.g., welding, but a method characterizing the actual dose delivered to the lungs would be preferable. Sampling of particles in exhaled breath can be used for the biomonitoring of both endogenous biomarkers and markers of exposure. We have explored a new method for the sampling of metals in exhaled breath from