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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193156 hits

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Background The scaphoid is the most commonly fractured carpal bone in adults as well as in children. Previous studies have reported a wide range of fracture incidences. Scaphoid fractures and non-unions in children have been sparsely investigated. Aim To perform a systematic review of the current literature on epidemiology of scaphoid fractures and non-unions in adults and children. Methods An ele

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Ultrathin films of quaterthiophene (4T) were deposited on a Ag(111) surface by vacuum sublimation and characterized with respect to their geometric and electronic properties using several surface-sensitive techniques. For the monolayer (1 ML), a long-range ordered superstructure is found by electron diffraction (LEED). This is commensurate to the Ag(111) surface due to covalent bonding of the "fla

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The characterization of exoplanets and their birth protoplanetary disks has enormously advanced in the last decade. Benefitting from that, our global understanding of the planet formation processes has been substantially improved. In this review, we first summarize the cutting-edge states of the exoplanet and disk observations. We further present a comprehensive panoptic view of modern core accret

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Aim: To identify responders to continuous glucose monitoring (CGM) in relation to reductions in HbA1c and percentage of time spent in hypoglycaemia after initiation of CGM for individuals with type 1 diabetes treated with multiple daily insulin injections. Materials and Methods: We analysed data from 142 participants in the GOLD randomized clinical trial. We evaluated how many lowered their HbA1c

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A push-pull oscillator topology that uses only one type of active device is proposed in this article. A magnetic transformer is leveraged to set positive feedback around a common-collector differential npn transistor pair, implementing the push-pull operation. This results in half the bias current for a given amplitude of oscillation, compared to more standard oscillator topologies. A thorough pha

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Objectives: To evaluate the effect of preoperative malperfusion on 30-day and late mortality and postoperative complications using data from the Nordic Consortium for Acute Type A Aortic Dissection (ATAAD) registry. Methods: We studied 1159 patients who underwent ATAAD surgery between January 2005 and December 2014 at 8 Nordic centers. Multivariable logistic and Cox regression analyses were perfor

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An inferior dermal flap (“sling”) can be used to cover an implant with two layers of tissue following Wise pattern skin-reducing mastectomies. Here, we performed a systematic review of the risks and benefits of this technique, specifically regarding complications, patient-reported outcomes, and aesthetic outcomes. PubMed and other relevant databases were searched using specific key words, with inc

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Several studies have shown that there is a strong physical interaction between cholesterol and sphingomyelin (SM). The critical factor is thought to be the high degree of saturation in the very long acyl chains of SM. In this study we examined the effects of SM on cholesterol absorption in the rat and compared them with those of phosphatidylcholine (PC). Cholesterol absorption was studied by use o

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Background: Studies on the incidence of Cushing’s disease (CD) are few and usually limited by a small number of patients. The aim of this study was to assess the annual incidence in a nationwide cohort of patients with presumed CD in Sweden. Methods: Patients registered with a diagnostic code for Cushing’s syndrome (CS) or CD, between 1987 and 2013 were identified in the Swedish National Patient R

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A new formulation of explicit multistep methods allows variable step-sizes by construction. This formulation can be used to construct time-adaptive strong stability preserving (SSP) multistep methods of any order for the solution of time-dependent PDEs. The new formulation is implemented in a MATLAB package, and some numerical examples are presented.

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Background: Chronic pain patients frequently suffer from psychological symptoms. There is no consensus concerning the prevalence of severe anxiety and depressive symptoms and the strength of the associations between pain intensity and psychological distress. Although an important aspect of the clinical picture is understanding how the pain condition impacts life, little is known about the relative

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Solitary insects that feed on floral nectar must use innate knowledge to find their first flower. While innate preferences for flower colours are often described as fixed, species-specific traits, the nature and persistence of these preferences have been debated, particularly in relation to ontogenetic processes such as learning. Here we present evidence for a strong context-dependence of innate c

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Summary: Laboratory microcosm experiments using protists as model organisms have a long tradition and are widely used to investigate general concepts in population biology, community ecology and evolutionary biology. Many variables of interest are measured in order to study processes and patterns at different spatiotemporal scales and across all levels of biological organization. This includes mea

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Digital work has become part of social workers’ daily routines in countries where digitalisation is on the agenda. As a consequence, documentation practices are expanding—on paper as well as digitally—and include reporting detailed statistics about client interventions, filling in digital forms, and fulfilling local and national performance measurement goals. Standardised formulas with tick-box an

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Light levels in terrestrial and shallow-water environments can vary by ten orders of magnitude between clear days and overcast nights. Light-evoked pupillary responses help the eyes of animals perform optimally under these variable light conditions by balancing trade-offs between sensitivity and resolution [1]. Here, we document that the mirror-based eyes of the bay scallop Argopecten irradians an