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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192286 hits

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The platelet-derived growth factor (PDGF) alpha and beta receptors undergo dimerization as a consequence of ligand binding. Depending on the PDGF isoform (PDGF-AA, -AB or -BB), homodimers or heterodimers of receptors are formed. In this study, we have used transfected porcine aortic endothelial cells, coexpressing cDNAs for the alpha receptor and the beta receptor at comparable levels, to investig

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The Nhandugue River flows over the western margin of the Urema Rift, the southernmost extension of the East African Rift System, and marks the north-western border of Gorongosa National Park, Mozambique. It constitutes one of the major indispensable water resources for the ecosystem that the park protects. Our study focused on the hydrogeological conditions at the western rift margin by resistivit

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BACKGROUND: Female genital mutilation (FGM) is commonly practiced mainly in a belt reaching from East to West Africa north of the equator. The practice is known across socio-economic classes and among different ethnic, religious, and cultural groups. Few studies have been appropriately designed to measure the health effects of FGM. However, the outcome of FGM on intersex individuals has never been

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This thesis covers aspects of the mature human B cell and its different guises on its way to become a fully differentiated antibody forming plasma cell (AFC), the key player in the humoral immune system. The understanding of the complex molecular mechanisms taking place in the B cell, as it first encounters antigen, enters the germinal center (GC) reaction, giving rise to memory cells and plasma c

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Popular Abstract in Swedish Insekter kommunicerar med dofter. De artspecifika kemiska substanser som används mellan individer kallas feromoner. Hos sädesbroddflyet, Agrotis segetum, producerar honan en "parfym", ett sexualferomon som består av flera komponenter, för att locka till sig en hane. På hanens antenner finns lukthår med särskilda motagare, receptorer, som används för att detektera honansA number of analogues of (Z)-5-decenyl acetate (1), a pheromone component of the turnip moth, Agrotis segetum, have been synthesised and tested by using single-cell electrophysiology, in order to investigate the relationships between structure and activity, and to elucidate the interactions between 1 and its receptor. Molecular mechanics and ab initio quantum mechanical calculations have been used

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The landscape in global international economic relations has experienced major upheavals during the past decade. On the one hand, major economic powers abandon the principles of multilateralism and open trade, on the other, emerging players like China increasingly gain influence, firmly advancing their interests with extensive projects such as the Belt and Road Initiative (BRI). The EU, rightly se

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The EU, being the largest trading partner for many developing countries, offers a General Scheme of Preferences (GSP) as a voluntary trade promoting scheme. Through GSP+, an extension of GSP, the EU offers additional market access conditional on commitment to sustainable development and good governance. Using a Gravity Equation, I find insignificant trade creating effects on GSP+ in comparison wit

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Hälften mjölk, hälften fail? Fallstudien syftar till att undersöka vilka attityder som går att urskilja gentemot Arlas varumärkesförlängning av sin Laktosfria Mjölk- och Havredryck samt vilka faktorer som påverkar formandet av dessa attityder. Detta för att få en förståelse för hur en varumärkesförlängning utifrån ett konsumentperspektiv kan påverka modervarumärkets varumärkesvärde. Det empiriska Half milk, half fail? The case study aims to investigate how Arla’s brand extension of an Milk- and oat drink from a consumer perspective is evaluated and perceived compared to Arla’s own view of the extension. Thus to gain an understanding of how a brand extension of a distinctive product category can affect Arla’s brand equity. Through a netnographic observation on social media, a semi-structure

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This paper estimates and simulates a New-Keynesian small-scale DSGE macro model. The model consists of the hybrid forms of the Phillips curve and the IS curve, and is closed with a Taylor-type feedback rule allowing partial adjustment of the monetary policy instrument. We estimate the three-equation system simultaneously on Swedish data 1995:Q1 to 2014:Q4 with the FIML estimator. The empirical par

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This is the report for a master thesis work which concerns the challenge of automating a reach stacker. A reach stacker is a vehicle that lifts and moves containers. This report should be seen as a preliminary study which handles automation concepts, simulations and sensors. Research questions answered are: Which areas would benefit most from driver assistance, What kind of control is needed for t

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In the spring of 2005, the Treaty Establishing a Constitution for Europe (CT) was rejected in French and Dutch referenda. The document, that was to lead the recently expanded European Union (EU) into the future, was instead put on pause for reflection. Why was there such fear and scepticism towards the CT? What was the CT really all about? In this analysis of the CT, I look at the CT from three le

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Fulltext är ej tillgänglig i elektronisk form. För lån/kopia av tryckt uppsats kontakta Medicinska fakultetens bibliotek, Lunds universitet

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As a consequence of the information society, smart and specialized IT based system, such as Warehouse Management Systems, have been developed to harness the increasing flow of information. While they are designed to increase the efficiency in the warehouse, the implementation of them requires the warehouse implementing it to adjust to the new environment it creates. This adaption have proven hard

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This thesis presents a Cost Benefit Analysis of a potential relocation of Malmö Konstmuseum. The main purpose of this research is to inform decision makers and assist the political discussion around this subject. In this study, the net social benefits are estimated for both the new and current locations. On the benefit side, use value, non-use value and museum revenues are accounted for, while on

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The purpose of the thesis is to investigate how social and cultural factors influence the decision making behaviour regarding publicly displayed items, using the outdoor space as an example. We want to provide a more dynamic view on decision making concerning publicly displayed products, taking the personalities of the consumers into consideration. By using a qualitative research design we found t