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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193185 hits

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Globally, a substantial number of children experience various forms of parental maltreatment. Child protection agencies work to support these children and prevent further abuse or neglect, often through targeted interventions directed at the parents. Previous research has indicated that social workers may approach male and female perpetrators of maltreatment differently once a case is reported. To

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The evolution of male courtship rituals has traditionally been attributed to female mate selection, but may also hinge on male investment strategies in sexually cannibalistic species. In many spiders, males perform energetically costly courtship rituals to increase acceptance by females and minimise the risk of sexual cannibalism. However, due to sperm competition, males may invest less energy whe

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Carbon capture and storage (CCS) has in recent years gained increasing attention as a climate solution. In Denmark, geological CO2-storage was earlier rejected, but in 2020 CCS was incorporated into national climate policy as key to reach the country’s 2030 target. In this article we investigate the incorporation of CCS into Danish climate policy as a case of mitigation deterrence. Through the con

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Abstract INTRODUCTION Countries have varying, limited healthcare budgets for emerging disease-modifying therapies. Cost-effectiveness analysis, combined with country-level cost-effectiveness thresholds, can be used to estimate value-based prices (VBPs) for lecanemab and donanemab across 174 countries. METHODS The cost-effectiveness of lecanemab and donanemab was estimated using incremental cost an

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Background: Isothiazolinones are widely used as preservatives in both cosmetic and non-cosmetic products. Sensitisation to isothiazolinones other than chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT), present in the baseline series, is increasing. Objectives: To investigate the prevalence of sensitisation to benzisothiazolinone (BIT) in comparison to CMIT/MIT and to develop a product-i

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Neurofilament light chain (NfL) is a promising biomarker of axonal injury across acute and chronic neurodegeneration, which can improve drug discovery and disease monitoring models. Traditional in vivo animal models cannot fully mimic human pathophysiology of neurodegenerative diseases (NDDs), but in vitro models based on human cells solve this problem, reducing the time and cost of drug testing.

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Populärvetenskaplig sammanfattning: Under alla tider har planeten Jorden genomgått en naturlig klimat variation. Utöver denna naturliga variation i klimatet, så har människan, under det senaste århundradet, medverkat till en ökning av växthusgaser i atmosfären. Detta kan innebära att växthuseffekten intensifieras och Jorden bli utsatt för onaturliga temperaturökningar. Koldioxid (CO2), från bland In the context of climate change, it is important to understand how the terrestrial carbon cycle is interacting with the anthropogenic increase in atmospheric carbon dioxide (CO2) concentration. Boreal and subarctic regions in the northern hemisphere are great carbon pools, as well as they are subject to predicted warming. These facts place them in the absolute frontline of ecosystems that are to

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Fairtrade represents a small but rapidly growing share of the world market. This paper discusses Fairtrade impact on the coffee value chain. Both Fairtrade and the coffee value chain link together the producer and the consumer. This is of importance as the geographical distance between where most coffee is produced and consumed can be great and level development often varies widely. In Northern co

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Gas in Scattering Media Absorption Spectroscopy (GASMAS) is a near-infrared (IR) optical spectroscopy technique showing great potential in the continuous, non-invasive monitoring of the lungs. While the feasibility of GASMAS has been proven in neonatal lung studies, applying the technique to older children and adults is challenging. The increased tissue thickness strongly attenuates the signal, ne

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This paper focuses on the detection of structural breaks in the second-order matrices of multivariate time series. A comprehensive simulation-based comparison is conducted to measure the performance of three widely cited nonparametric methods that allow for serial dependence in the data: the pure CUSUM procedure with binary segmentation in Aue et al., (2009), the CUSUM-based sparsified binary segm

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This thesis project, initiated by Thule, aimed to develop a concept for a foldable roof box. The goal was to create a solution that is easier to handle and store than traditional roof boxes, which are often perceived as bulky and difficult to manage when not in use. The project followed a design process based on the Double Diamond model, Human-Centered Design, and Thule’s internal development pro

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Amid an escalating climate crisis, Germany faces growing political polarisation and declining support for climate policy. The mobility transition has emerged as a symbolic and emotionally charged ‘cultural battleground’, where debates around fossil-fuel dependency are deeply entangled with identities and power structures. This study examines the role of hegemonic masculinities in shaping socio-pol

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In communication and management research, employee voice has been widely acknowledged as a central component for organizations long term development and survival. With the increasing digitalization and need for flexibility, digital workplace meetings have become a common form of communication, demonstrating a new arena where employee voice is expressed and shaped. Thus, the aim of this study is to

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There exists a lack of laser-based remote sensing methods that give signals with high intensity and directionality. According to previous research, mirrorless lasing can meet these requirements; however, neither the dependence on the gain medium geometry nor the light-matter interaction responsible for the emission has been investigated in detail. This thesis project examined the sideways lasing e

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This thesis presents the evolution, design, and test of an Orthogonal Frequency Division Multiplexing (OFDM) based radar system. The application of this research question involves the implementation of an Integrated Sensing and Communication (ISAC) radar system that can be seamlessly integrated into existing wireless communication networks. The primary objective of this thesis project is to integr

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Social relationships and group membership shape cognitive functions, including memory. One memory function contributing to knowledge acquisition is the ability to draw novel conclusions by linking overlapping but distinct episodic memories, a process called associative inference. Prior research shows that both general memory and associative inference for arbitrary objects are enhanced when materia

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This paper examines how institutional vulnerabilities are reproduced, institutionalised, and solidified through the translation of legal norms within Japan’s new admission policy, the Employment for Skill Development (ESD) system. Japan has de facto accepted foreign workers for over three decades by granting various residence statuses to address its declining birthrate and labour shortage. However