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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193185 hits

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The role of women in post-conflict countries in Africa has always been less prioritised when working for reconciliation. Our aim in this thesis is to compare how the gacacas in Rwanda and TRC´s in South Africa treated the suffering of, and justice for women and what healing processes were put in place to help them. Truth Commissions are a form of reconciliation theory which will be further analyse

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An extensive public health literature has linked the low take-up of healthcare services in developing countries with measures of accessibility such as distance, duration and cost of travel to the nearest health facility. However, causality has been difficult to prove, given the endogeneity of factors influencing access, such as the availability and quality of roads and transportation. Using a natu

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Telematics units are widely spreading in the automotive industry. Getting realtime data from the systems is essential for creating services in the back office which builds value for both companies and end customers. The services created greatly impact maintenance strategies, future developments, and keeping the vehicle more sustainable and secure for both end users and customers. However, adding n

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Bakgrund: Utbrändhet, klassificerad som utmattningssyndrom (ICD-10-kod F43.8A), är ett stressrelaterat tillstånd som uppstår till följd av bland annat långvarig exponering för hög arbetsbelastning utan tillräcklig återhämtning. Yoga diskuteras inom forskning som en potentiell intervention för att minska faktorer, såsom långvarig arbetsrelaterad stress och sömnsvårigheter, vilka på sikt kan leda ti

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A major inefficiency in contemporary agriculture arises from food-feed competition, where limited agricultural resources are used to produce animal feed instead of human-edible crops. Due to factors like metabolic losses and waste, this is often less resource efficient. This thesis investigates the optimal number of cattle in the Swedish agricultural system when aiming to maximise protein producti

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The saturation of the IJTAG concept and its approval as the IEEE 1687 standard in 2014 has generated a wave of research activities and created demand for a set of appropriate and challenging benchmarks. This paper presents such a set developed by an industrial and academic consortium and constructed in a way that facilitates objective comparison of experimental results across research groups as we

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Background and purpose — Patient-specific instrumentation (PSI) in total knee arthroplasty (TKA) aims to improve implant alignment and clinical outcomes, but its effectiveness remains uncertain. We aimed to compare whether PSI was superior to conventional instrumentation (CVI) in TKA. The primary outcome was the Oxford Knee Score (OKS) at 2 years with assessments of additional clinical outcomes up

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Introduction: HIV guidelines recommend switching from a three-drug regimen (3DR) to dolutegravir + lamivudine (DTG+3TC) for eligible individuals. This retrospective national cohort study used Swedish InfCareHIV registry data to evaluate long-term outcomes of adults with HIV RNA <50 copies/ml who switched to DTG+3TC or a guideline-recommended 3DR between July 2019 and May 2023 in routine clinical c

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Introduction: Strengthening Primary Health Care (PHC) is essential for building resilient and equitable health systems, but PHC faces barriers in implementation, resource allocation, and political prioritisation. This study aimed to develop a strategic roadmap to enhance PHC by identifying core values, priorities, and actionable strategies through expert consensus. Methods: A two-round Delphi stud

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Globally, a substantial number of children experience various forms of parental maltreatment. Child protection agencies work to support these children and prevent further abuse or neglect, often through targeted interventions directed at the parents. Previous research has indicated that social workers may approach male and female perpetrators of maltreatment differently once a case is reported. To

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The evolution of male courtship rituals has traditionally been attributed to female mate selection, but may also hinge on male investment strategies in sexually cannibalistic species. In many spiders, males perform energetically costly courtship rituals to increase acceptance by females and minimise the risk of sexual cannibalism. However, due to sperm competition, males may invest less energy whe

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Carbon capture and storage (CCS) has in recent years gained increasing attention as a climate solution. In Denmark, geological CO2-storage was earlier rejected, but in 2020 CCS was incorporated into national climate policy as key to reach the country’s 2030 target. In this article we investigate the incorporation of CCS into Danish climate policy as a case of mitigation deterrence. Through the con

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Abstract INTRODUCTION Countries have varying, limited healthcare budgets for emerging disease-modifying therapies. Cost-effectiveness analysis, combined with country-level cost-effectiveness thresholds, can be used to estimate value-based prices (VBPs) for lecanemab and donanemab across 174 countries. METHODS The cost-effectiveness of lecanemab and donanemab was estimated using incremental cost an

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Background: Isothiazolinones are widely used as preservatives in both cosmetic and non-cosmetic products. Sensitisation to isothiazolinones other than chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT), present in the baseline series, is increasing. Objectives: To investigate the prevalence of sensitisation to benzisothiazolinone (BIT) in comparison to CMIT/MIT and to develop a product-i

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Neurofilament light chain (NfL) is a promising biomarker of axonal injury across acute and chronic neurodegeneration, which can improve drug discovery and disease monitoring models. Traditional in vivo animal models cannot fully mimic human pathophysiology of neurodegenerative diseases (NDDs), but in vitro models based on human cells solve this problem, reducing the time and cost of drug testing.

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Populärvetenskaplig sammanfattning: Under alla tider har planeten Jorden genomgått en naturlig klimat variation. Utöver denna naturliga variation i klimatet, så har människan, under det senaste århundradet, medverkat till en ökning av växthusgaser i atmosfären. Detta kan innebära att växthuseffekten intensifieras och Jorden bli utsatt för onaturliga temperaturökningar. Koldioxid (CO2), från bland In the context of climate change, it is important to understand how the terrestrial carbon cycle is interacting with the anthropogenic increase in atmospheric carbon dioxide (CO2) concentration. Boreal and subarctic regions in the northern hemisphere are great carbon pools, as well as they are subject to predicted warming. These facts place them in the absolute frontline of ecosystems that are to

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Fairtrade represents a small but rapidly growing share of the world market. This paper discusses Fairtrade impact on the coffee value chain. Both Fairtrade and the coffee value chain link together the producer and the consumer. This is of importance as the geographical distance between where most coffee is produced and consumed can be great and level development often varies widely. In Northern co