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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192330 hits

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In this study the probable outcome of the construction of the Grand Ethiopian Renaissance Dam is investigated. At the same time an attempt is made to derive general factors that can determine whether a common source of water leads to conflict or cooperation between states. This is done by contrasting two different theories regarding conflict and cooperation over water in a heuristic case study. Th

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The inherent properties of cells and micro-organisms is an under-explored source of specificity for particle sorting. In contrast to standard immunolabeling it allows us to perform fractionation without any chemical preparation of the sample. This improves the accessibility and affordability of the technology. Our contribution in the field is to extend the scope of deterministic lateral displaceme

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Asparagine-linked glycosylation 13 homolog (ALG13) encodes a nonredundant, highly conserved, X-linked uridine diphosphate (UDP)-N-acetylglucosaminyltransferase required for the synthesis of lipid linked oligosaccharide precursor and proper N-linked glycosylation. De novo variants in ALG13 underlie a form of early infantile epileptic encephalopathy known as EIEE36, but given its essential role in g

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An optimal network design was carried out to prioritise the installation or refurbishment of greenhouse gas (GHG) monitoring stations around Africa. The network was optimised to reduce the uncertainty in emissions across three of the most important GHGs: CO2, CH4, and N2O. Optimal networks were derived using incremental optimisation of the percentage uncertainty reduction achieved by a Gaussian Ba

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A new negligible depletion extraction procedure was proposed for equilibrium sampling of 4-tert-octylphenol (OP) and 4-nonylphenol (NP) into a thin film of 1-octanol supported on a hollow fiber membrane. This thin liquid film extraction technique was directed at the determination of ( 1) freely dissolved concentrations, ( 2) distribution coefficients to 1-octanol (D-ow), and ( 3) binding to dissol

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Purpose: The knowledge about young adults who have lost a parent to cancer is limited, and to reach a broader understanding about this group, this study used the Dual Process Model of Coping with Bereavement (Stroebe and Schut, 1999) as a theoretical framework. The purpose of this study was to describe loss- and restoration-oriented bereavement stressors and psychosocial wellbeing of young adults

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Objectives: Recent evidence from the 7-year followup of the Pediatric Osteoporosis Prevention (POP) study indicates an inverse correlation between years of participation in a physical activity (PA) intervention and fracture risk in children. However, we could not see a statistically significant reduction in fracture risk, which urged for an extension of the intervention. Setting: The study was con

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Context. The ESA Gaia mission provides a unique time-domain survey for more than 1.6 billion sources with G ≲ 21 mag. Aims. We showcase stellar variability in the Galactic colour-absolute magnitude diagram (CaMD). We focus on pulsating, eruptive, and cataclysmic variables, as well as on stars that exhibit variability that is due to rotation and eclipses. Methods. We describe the locations of var

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Pursuit of the Bioeconomy (BE) and the Circular Economy (CE) is high on the political agendas of many countries. Application of the concepts is intended to ameliorate a number of sustainability challenges, such as raw material constraint concerns and global warming. The concepts of BE and CE are increasingly combined to describe a ‘circular bioeconomy’ (CBE), which emphasises value retention for r

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Background: Calcium overload is a major cause of reperfusion myocardial injury. Multidetector computed tomography (MDCT) has been previously used in visualizing coronary artery calcium, but not calcium deposits in reperfused infarction. Purpose: To assess the ability of MDCT to 1) noninvasively visualize and characterize calcium deposits in reperfused infarcts, and 2) monitor regional wall swellin

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The use of Intelligent control schemes in Nonlinear Model Based Control (NMBC) has gained widespread popularity. Neural Networks, in particular, have been used extensively to model the dynamics of nonlinear plants. However, in most cases, these models do not lend themselves to easy maneuvering for controller design. Therefore, a common need is being felt to develop intelligent control strategies t

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In the study presented in this paper, the effect of different vehicle driving cycles on the pneumatic hybrid has been investigated. The pneumatic hybrid powertrain has been modeled in UT-Power and validated against experimental data. The GT-Power engine model has been linked with a MATLAB/simulink vehicle model. The engine in question is a single-cylinder Scania D12 diesel engine, which has been c

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The main challenge for a pediatric hemato-oncologist today is to obtain a cure for the sick child with the minimum of treatment-related complications. Children on their way to achieving adulthood face many risks after hematopoietic SCT (HSCT). Continuous follow-up includes assessment of organ function, focus on vaccinations and screening for secondary malignancies. Updated treatment protocols are

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BACKGROUND: Morphologic examination of bone marrow and peripheral blood samples continues to be the cornerstone in diagnostic hematology. In recent years, interest in automatic leukocyte classification using image analysis has increased rapidly. Such systems collect a series of images in which each cell must be segmented accurately to be classified correctly. Although segmentation algorithms have

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Packaging affects the logistical and environmental efficiency of supply chains. The purpose is to increase knowledge of the current state, trade-offs and improvement potential of packaging logistics in supply chain practice. The research is based on 22 cases, each of which consists of supply chain mapping and structured interviews with three supply chain actors (manufacturer, distributor and retai

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ydrophobically modified polymers (HM-P) typically behave as thickeners in a wide range of systems. The thickening effect in an aqueous solution of this kind of polymer depends on intermolecular hydrophobic associations and also on chain entanglements if the polymer concentration is significantly above the overlap concentration. In the present investigation a rather short end-capped polymer has bee