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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192238 hits
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The purpose of this thesis is to address the complexity of board involvement in the dynamic collaborative environment of joint ventures and, thereby, contribute to joint venturing and corporate governance literature. The researchers propose a model of an adaptive governance system wherein the board acts as a self-correction system, influencing and being influenced by the dynamics and complexity of
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Supramolecular chemistry is a field in which noncovalent interactions between molecules are utilised to promote the formation of larger molecular assemblies. A single monomer consisting of a bicyclo[3.3.1]nonane backbone equipped with hydrogen bonding motifs and solubilising groups is synthesised. Utilisation of different hydrogen bonding motifs and appropriate solvent renders self-aggregation of
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Equity crowdfunding has achieved a high popularity in the UK throughout the last years. However, most researchers within this field primarily focused on the success factors of an equity crowdfunding campaign while only little is known about the post-campaign effects. Therefore, the aim of this thesis is to determine which patterns of characteristics successfully equity crowdfunded companies that r
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Examensarbetet syftar till att ge ett fo¨rslag till ett fo¨retag som vill uto¨ka sin verksamhet i en redan existerande byggnad. Byggnaden, som a¨r ett gammalt stall, a¨r bela¨gen i utkanten av Ba°rslo¨v. En liten del av stallet har redan renoverats om till ett par la¨genheter som kunden, Aplaga°rden B & B och vinga°rd, hyr ut i dagsla¨get. Ba°rslo¨vs omra°det har en va¨ldigt gammal historia oc
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Children using mechanical ventilation for survival represent a small, but growing, vulnerable population in society. The aim of this study was to describe the existing qualitative research that examined family members' experiences when a child is dependent on ventilator at home. A metasynthesis is an interpretative integration of qualitative research findings based on a systematic literature searc
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AIM: It has been suggested that intact cord resuscitation can reduce the risk of brain damage. We investigated the effects on neurodevelopment at two years of age.METHODS: This study was performed in Kathmandu, Nepal. In 2016, 231 late preterm and term infants born vaginally and not breathing were randomised to resuscitation with an intact cord or the standard practice of early cord clamping (CC).
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Asparagine-linked glycosylation 13 homolog (ALG13) encodes a nonredundant, highly conserved, X-linked uridine diphosphate (UDP)-N-acetylglucosaminyltransferase required for the synthesis of lipid linked oligosaccharide precursor and proper N-linked glycosylation. De novo variants in ALG13 underlie a form of early infantile epileptic encephalopathy known as EIEE36, but given its essential role in g
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Human histo-blood groups are inherited polymorphic variants that occur in the molecular structures on the humanred blood cell (RBC) surface. Introducing foreign RBCs into a recipient lacking an antigen may activate the humoraldefence leading to a hemolytic transfusion reaction. Antigenic differences can also cause hemolytic disease of thefetus and newborn (HDFN). Blood group antigens are implicate
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Climate change has likely altered high-latitude forests globally, but direct evidence remains rare. Here we show that throughout a ≈1000-km transect in Scots pine (Pinus sylvestris L.) forests in Sweden, mature trees in ≈2015 had longer needles with shorter lifetimes than did trees in ≈1915. These century-scale shifts in needle traits were detected by sampling needles at 74 sites from 2012 to 2017
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The inherent properties of cells and micro-organisms is an under-explored source of specificity for particle sorting. In contrast to standard immunolabeling it allows us to perform fractionation without any chemical preparation of the sample. This improves the accessibility and affordability of the technology. Our contribution in the field is to extend the scope of deterministic lateral displaceme
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The binding between colipase and two triacylglycerol substrates, tributyrin and Intralipid, in the presence of bile salts have been determined quantitatively by a method based on equilibrium partition in an aqueous two-phase system. In the model proposed the triacylglycerol, in the form of spherical droplets covered with bile salt, is assumed to have a certain number of independent binding sites a
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Studies on fluids at supercritical pressure have been developed in a rapid-growth manner so that geometries are not restricted to circular tube. This paper is devoted to conduct a brief review of the recent main experiments on supercritical fluids such as CO 2
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Understandability of the current system is a key issue in most reengineering processes. An architecture description of the system may increase its understandability. This paper presents experiences from architectural design recovery in a product family of large distributed, embedded systems. Automated recovery tools were hard to apply due to the nature of the source code. A qualitative evaluation
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The novel structure of the δ1 phase in the cobalt-zinc system was determined by single-crystal X-ray diffraction. The structure features fused double icosahedra linked by edge-and face-sharing. The δ1-CoZn7.8 structure is incommensurately modulated along the columnar b direction. The extent of the linear pentagonal antiprismatic intergrowth is limited to a maximum of two overlapping icosahedra bec
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Violence features in human life, not only as actual physical confrontation but also as stories. Stories of violence are particularly important in violence-prone subcultures and among those partaking in the illegal drug economy. Drawing on narrative analysis, this study examines stories of violence among a population of incarcerated Norwegian drug dealers. Four widespread story types are identified
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Exercise is associated with increased peak bone mineral density (BMD). To determine the relationship between the duration of exercise and BMD, we measured BMD of the axial and appendicular skeleton by dual-energy X-ray absorptiometry (DXA), and speed of sound (SOS), broadband attenuation (BUA), and stiffness index by quantitative ultrasound (QUS) of the calcaneus, in 67 active male national soccer
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A number of deleterious health effects have been identified from exposure to outdoor airborne particulate matter. Given that in developed countries we spend majority of our time indoors, in private homes about 65 % (Brashe et al., 2005), the understanding of this exposure is important, yet knowledge is sparse. Particle levels indoors are affected by indoor sources, infiltration from outdoors or pa
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Deoxycytidine kinase (dCK) and deoxyguanosine kinase (dGK) catalyze the first step in the intracellular cascade of fludarabine (2-fluoroadenine-beta-D-arabinofuranoside) and cladribine (2-chlorodeoxyadenosine) phosphorylation, which leads to activation of these prodrugs, commonly used for treatment of chronic lymphocytic leukemia (CLL). Thus, resistance to nucleoside analogues may primarily be due
