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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193123 hits

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A pocket cavity is generated when the Low Pressure Turbine (LPT) is connected to the Outlet Guide Vane (OGV) in the rear part of a gas turbine engine due to the different conjugate diameters. This kind of pocket cavities, due to the high Reynolds number and the specific shapes, are hardly investigated in previous researches. The heat transfer distribution and fluid flow over the pocket cavity have

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Using information from Swedish population registries, we attempt to decompose the shared environment (C) into four subcomponents: close family, family, household, and community. Among pairs differing in their genetic and geographical/household relationships, we examine three externalizing syndromes: drug abuse (DA), criminal behavior (CB), and alcohol use disorders (AUD). The best-fitting common p

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Accumulating evidence demonstrates an association between dense infiltration of lymphocytes and prognosis in colorectal cancer (CRC), but whether this prognostic impact differs by tumour location remains unknown. This study investigated the prognostic impact of cytotoxic and regulatory T cells in CRC, with particular reference to the anatomical subsite of the primary tumour. The density of CD3+, C

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Tumor barrier function in carcinoma represents a major challenge to treatment and is therefore an attractive target for increasing drug delivery. Variables related to tumor barrier include aberrant blood vessels, high interstitial fluid pressure, and the composition and structure of the extracellular matrix. One of the proteins associated with dense extracellular matrices is fibromodulin, a collag

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Seen through the growth of progressive diversity policies it may appear that contemporary organizations are sites of equality. But although inclusion is the formally stated aim of many organizations, exclusionary pressures toward LGBT workers still challenge sexual minorities' access to full inclusion. A central concern in this paper is exploring how to understand inclusion in organizational conte

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Purpose: The inappropriate irrigation is accelerating the soil salinization in western irrigation districts of China. The amelioration of salinized land must be based on large amount of water content and salinity data. Plastic coated TDR has been designed to measure water content accurately in highly saline soil, but the soil bulk electrical conductivity cannot be measured due to the coated materi

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A numerical study is performed to investigate the effects of various discrete rib configurations on the heat transfer and fluid flow characteristics of a rotating rectangular straight channel (aspect ratio of 2:1) with 45° orientation. Three parameters of the discrete rib configuration - rib streamwise distance, rib widthwise distance, and inner-half-rib angle - are examined based on a continuous

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Background Childhood cancer has been associated with long-term risk of urinary tract diseases, but risk patterns remain to be comprehensively investigated. We analysed the lifetime risk of urinary tract diseases in survivors of childhood cancer in the Nordic countries. Methods We identified 32,519 one-year survivors of childhood cancer diagnosed since the 1940s and 1950s in the five Nordic cancer

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Objective: Public stigma of mental illness is still a major problem where numerous population studies during the last decade have mainly shown no improvements. A Swedish national antistigma campaign has been running 2010–2014. The aim of this study was to investigate changes in public stigma during this period as compared to baseline in 2009. Methods: Yearly population surveys were made between 20

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Ethiopia is currently facing the worst drought in its modern history, resurrecting the world’s collective memory of the tragedy of the 1980s. But such severe meteorological conditions may not be so rare in the future: the observed and projected impacts of changing climatic conditions in Ethiopia point towards a considerable worsening of food security status for many smallholder households. In our

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Background: Neuromyelitis optica (NMO)-systemic lupus erythematosus (SLE) association is a rare condition characterized by multiple autoantibodies. Objective: To examine if, during the evolution of NMO, anti-AQP4 responses are part of polyclonal B cell activation, and if T cell responses contribute. Methods: In 19 samples of six patients who developed NMO during SLE, we examined the correlation of

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Several authors have reported problems on service courses in basic probability and statistics: students may lack motivation, find the theory difficult or boring, others see no applications for the results. To remedy these problems we have developed a learning environment where two important components are applied problems and use of technology. However, the mere existence of applied problems and t

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We identify the socioeconomic determinants of three levels of antenatal care (ANC) visits (no, intermediate [1–3], and recommended [≥4]) in Bangladesh using a behavior model framework for health care utilization. Using multinomial logistic regression, we found that different levels of visits had different determinants; for example, media exposure increased the likelihood of intermediate compared w

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This article explores the role of informality among Uzbek construction workers in Russia. We start from a relationship that is based on economic reward and common interests and go on to explore the non-economic components of this relationship. Economically, the workers entrust their supervisor and agree to work for him for a given amount of money. However, this decision is also embedded in a non-e