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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193123 hits

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Objective: To evaluate aggrecanase activity after traumatic knee injury in a rat model by measuring the level of aggrecanase-generated Ala-Arg-Gly-aggrecan (ARG-aggrecan) fragments in synovial fluid, and compare with ARG-aggrecan release into joint fluid following human knee injury. To evaluate the effect of small molecule inhibitors on induced aggrecanase activity in the rat model. Method: An enz

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Fatigue is frequently reported by patients with mental illness. The multidimensional fatigue inventory (MFI-20) is a self-assessment instrument with 20 items including five dimensions of fatigue. The purpose of this study was to examine the test-retest reliability, internal consistency, convergent construct validity and feasibility of using MFI-20 in patients with schizophrenia spectrum disorders.

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Oncogenic mutants of c-Kit are often found in mastocytosis, gastrointestinal stromal tumors and acute myeloid leukemia. The activation mechanism of the most commonly occurring mutation, D816V in exon 17 of c-Kit, has been well-studied while other mutations remain fairly uncharacterized in this respect. In this study, we show that the constitutive activity of the exon 11 mutant V560D is weaker than

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Objective: Microbial manipulations in early life can affect gut development and inflammatory status of the neonate. The maternal diet during pregnancy and lactation also influences the health of the offspring, but the impact of maternal high-fat (HF) feeding along with modulations of the gut microbiota on body weight, fat deposition and gut function in the offspring has been poorly studied. Method

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The promotion of renewable energy sources (RES) has become a key measure within the EU to improve energy security and to mitigate climate change while offering opportunities for industrial development, job creation and regional cohesion. Over time this has put pressure for EU-level coordination and harmonization of national RES policy measures in order to improve effectiveness and market efficienc

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Industrial Symbiosis (IS) is a tool that may facilitate coordination of the factors necessary to improve resource use efficiency in regional levels. This thesis studies the potential of developing an IS network in rural Portugal, that could support the competitiveness of the local companies, whilst also improving their own and the regions environmental profile. The research is based on a hybrid o

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This study aims to identify the key leverage points of local tourism on Öland in which work can be initiated to bring about a more sustainable development of the tourism industry. To achieve this, an analysis was made of the tourism industry on Öland, and a methodological framework called The Öland Model developed for the initiation of a project to stimulate thinking among the actors on the island

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Micro credit has become a popular tool in the fight against poverty. All over the world, economists and practitioners have adopted the topicality. At the same time, an increased awareness of the situation of women is noticeable. In particular, marginalized women are discussed since they face poverty, illiteracy, low caste/casteless and gender gap. In the Indian South-eastern state of Tamil Nadu,

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Tre borrkärnor bestående av sjösediment, vardera 1.5 meter långa, från Byestadsjön i Småland, Sverige studerades med hjälp av mineralmagnetiska- kol- pollen- och röntgenflourosens (XRF)- analyser. Målet med studien var att rekonstruera tidig Holocen miljö, med fokus på tiden mellan 9000-7000 år sedan och därmed avgöra om det kalla klimatåterslaget cirka 8200 före nutid påverkade regionen eller ej.Three sediment cores, each 1.5 meters in length, obtained from Lake Byestadsjön in the province of Småland, southern Sweden were studied with high resolution mineral magnetic measurements, carbon content, pollen analysis and XRF analysis. The aim was to reconstruct the early Holocene environment, with focus on the period between 9000-7000 cal yr BP, and thereby conclude if the 8200 cal yr BP cooli

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The aim of this study was primarily to locate, describe and explain the impact of cultural differences on communication between Swedes and Canadians in Swedish-related companies in the Toronto area in Canada. In this we included communication between co-workers within the company, between the Swedish-related company and the Swedish mother company and between the Swedish-related company and other,

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The paper concerns the study of the relationship between international relations and the use of economic sanctions in the immediate post-cold war period. Interdependence, Neo-Realism and Democratic Theory are investigated from the perspective of answering the change in policy in western democracies. I second theoretical cut is given on the post-9/11 world order as a glimpse to what may come in th

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Abstract: Title: Dreaming of a Red Lamborghini and Blue Sky: Towards Understanding Sustainability and Sustainable Consumption in Developing Countries. Date of the Seminar: 1st June, 2010 Course: BUS 808 -Master thesis in International Marketing and Brand Management. Authors: Bishaara Hameed, Igor Ackerberg, Sundus Ahad Khan Advisors: Sofia Ulver-Sneistrup Keywords: Sustainability Discourses, Susta

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The purpose of this thesis was to examine how increased mobility of indigenous student migrants in Dhaka from the Chittagong Hill Tracts in Bangladesh affects notions of belonging and indigeneity. By applying a theoretical framework of mobility, global interconnectedness and lifestyle the study challenged representations by indigenous rights advocates of indigenous people as inherently immobile an

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Unlike other environmental threats, the loss of biodiversity is irreversible and the current and rapid loss of species is alarming. Several authors agree the state-owned protected areas are not sufficient to lessen biodiversity loss which is accentuated because most of the biodiversity is on private land. In this thesis, I study private conservation’s role as a tool for biodiversity conservation a

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The purpose of this paper is to contribute with a new understanding of pop-up stores through a phenomenological perspective by examining how consumers experience pop-up stores. The study also aims to look at a micro and macro perspective to better understand how this phenomenon links to and is shaped by macro level trends of the contemporary consumer culture. Given the purpose and aim of the repor