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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 194343 hits

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Abstract What are the pedagogical impacts of internationalisation on the development of higher education in Europe? How can we proceed in this process and take a pedagogical stance on the issue? This theoretical paper is partly based on a series of empirical studies conducted by the author, investigating students’ and teachers’ experiences and understanding of an internationalised educational cont

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Despite the recent theoretical and empirical advancements in the geography of innovation literature regarding the role that global sources of knowledge may have for regional growth and development, research in this field remains focused on successful regions and clusters in developed countries. Hitherto there has been limited research on the role of regions located in developing countries and the

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Background: Serum IgA antibodies against tissue transglutaminase (tTG) are reliable markers for celiac disease (CD), still the diagnostic performance of anti-tTG immunoassays can be improved. A novel ELISA, using fibronectin (FN) as tTG binding protein, was evaluated for the detection of anti-tTG antibodies in CD. Methods: Sera from 173 children with untreated CD and 97 controls were analyzed for

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Integrins are ubiquitous transmembrane receptors that play crucial roles in cell-cell and cell-matrix interactions. In this study, we have determined the effects of the loss of beta1 integrins in keratinocytes in vitro and during cutaneous wound repair. Flow cytometry of cultured beta1-deficient keratinocytes confirmed the absence of beta1 integrins and showed downregulation of alpha6beta4 but not

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Green, nonsulfur-like bacteria (GNSLB) and cyanobacteria form major components of microbial mats in both sulfidic and non-sulfidic hot springs and have been mainly studied in hot springs of Yellowstone National Park (YNP). These organisms synthesize specific lipid biomarkers Such as wax esters and long chain polyunsaturated alkenes (GNSLB) and heptadecane (cyanobacteria). We analyzed the lipid dis

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We present an experimental observation of the electronic Doppler effect in resonant Auger spectra upon core excitation slightly above the carbon K edge of the CO molecule. Thus the electronic Doppler effect has been identified in above-threshold excitation, and in a transition of Pi symmetry. Ab initio calculations of the potential energy curves of the relevant states of CO and the wave packet tec

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Carbon dioxide and methane fluxes were measured at a tundra site near Chokurdakh, in the lowlands of the Indigirka river in north-east Siberia. This site is one of the few stations on Russian tundra and it is different from most other tundra flux stations in its continentality. A suite of methods was applied to determine the fluxes of NEE, GPP, R-eco and methane, including eddy covariance, chamber

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An experimental investigation of heat transfer and fluid flow in a rectangular duct roughened by broken V-shaped ribs pointing upstream was carried out. The rectangular duct had art aspect ratio of 1/8, and the Reynolds number range was from 1000 to 6000. Liquid Crystal Thermography (LCT) was used to obtain the detailed heat transfer distributions on the ribbed wall. The main observed characterist

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The objective was to evaluate a screening procedure for detecting high-yield candidates for an OGTT, in a population of middle-aged Swedish women. A two-step screening procedure was performed in 6917 subjects. Women with a positive screening outcome, i.e. increased non-fasting capillary blood glucose, serum triglycerides, BMI, WHR, blood pressure or a family history of diabetes, pharmacological tr

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Objective: To examine the efficacy of sibutramine together with brief lifestyle modification for weight reduction in obese women with polycystic ovary syndrome (PCOS). Design: Investigator-initiated, multicenter, double-blind, randomized, parallel-group clinical trial. Setting: Departments of Obstetrics and Gynecology in primary care, referral centers, and private practice. Patient(s): Forty-two p

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Objective: Body mass index (BMI) is associated with increased incidence of cardiovascular disease (CVD). However, the risk could be very different for individuals with the same body mass. The present study explored whether regional fat distribution, as measured by waist-hip ratio (WHR), could modify the impact of BMI on the risk of CVD in men and women. Design: Prospective population-based study.