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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192973 hits

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Registered nurses' lived experience of preceptorship was studied in this phenomenological study. To illuminate the meaning of registered nurses' experience of being a preceptor for student nurses, individual tape-recorded interviews were conducted with 17 registered nurses. They narrated their experience of being a personal preceptor for student nurses during practical training on a hospital unit,

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We introduce a new notion of independence based on the Borel-Cantelli lemma. We study this characteristic in the context of i.i.d. stochastic processes and processes driven by equilibrium dynamics.

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The azimuthal distributions of photons and charged particles with respect to the event plane are investigated as a function of centrality in Pb-208 + Pb-208 collisions at 158 (.) A GeV/c in the WA98 experiment at the CERN SPS. The anisotropy of the azimuthal distributions is characterized using a Fourier analysis. For both the photon and charged particle distributions the first two Fourier coeffic

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The three-dimensional circulation, salinity distribution, and overall transport pattern were simulated in the Pearl River Estuary, China, using a modified version of the Princeton Ocean Model (POM). The circulation in the estuary is mainly driven by tide, wind, and river runoff in a complex manner, where the relative importance of the different forcing factors varies over the year. Field data on c

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The purpose of the article is to describe and compare the purchasing process for advanced versus basic logistics services. Further some specific observations are presented from the procurement of advanced third-party logistics services, with respect to service definitions, providers evaluations and contracts. The purchasing process of logistics services will in the future need to be more different

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Objective To estimate the cost-effectiveness of a new treatment (natalizumab) for multiple sclerosis (MS) compared with current standard therapy with disease-modifying drugs (DMDs) in Sweden. Methods A Markov model was constructed to illustrate disease progression based on functional disability (the Expanded Disability Status Scale (EDSS)). The effectiveness of natalizumab was based on a 2-year cl

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BACKGROUND: Adjuvant treatment with tamoxifen reduces the risk of contralateral breast cancer in hormone-responsive postmenopausal patients, whereas the effect in premenopausal women has not been fully elucidated. We have therefore studied the effect of tamoxifen on contralateral breast cancer in premenopausal women in a controlled randomised trial. PATIENTS AND METHODS: Premenopausal women (564)

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Density-dependent reproduction is commonly explained by either the habitat heterogeneity (HHH) or individual adjustment (IAH) hypothesis. Under the HHH, high quality territories are assumed to be occupied first. At higher density, occupation of low-quality territories increases due to lower availability of high-quality territories, which reduces mean reproductive success. Alternatively, the IAH as

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Basque is spoken by approximately 660,000 people (Trask 1997) in the Basque Country, straddling the border between northern Spain and southern France, particularly in rural areas of the Bizkaia and Gipuzkoa coastline, as well as inland Gipuzkoa and the foothills of the Pyrenees in Navarre. Virtually all Basque speakers are bilingual with either Spanish or French. Nevertheless, Basque is, due to it

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In patients undergoing peritoneal dialysis (PD) for end-stage renal failure, the optimum electrolyte composition of a dialysis solution is that which best serves the homeostatic needs of the body. Comparing the transperitoneal removal of electrolytes by conventional PD solutions (CPDSs) with that by normal kidneys, it is evident that peritoneal removal is in the lower range of what can be consider

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When distributed to different artefacts, the self appears in a multitude of shapes, characterized not only by its materiality but also by the necessity to preserve at least an illusion of a core self. The experience of a continuous evolution of these overlapping “selves”, many of which are materialized together with others’ overlapping selves, cannot be captured by traditional design approaches, n

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Fuel economy and emissions are the two central parameters in heavy duty engines; most of the existing heavy duty engines are run with diesel. The overall efficiency of diesel engines is good however they suffer from high levels of emissions mainly NOX and soot. Using alternative fuels like Natural-Gas has shown to be a good way to reduce emissions level. Diesel engines can be easily converted to N

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The main contribution of this work is a novel numerical characterization of a DNA sequence based on the 2-D graphical representation of DNA introduced by Yau et al. [12]. We construct a 3-tuple of the normalized leading eigenvalues of the Q matrices associated with the three characteristic curves of a DNA sequence. The approach is illustrated with an examination of dissimilarities of exon-1 of bet