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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192330 hits

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This is the first study which quantifies aggrecan fragments, stromelysin-1 and tissue inhibitor of metalloproteinases-1 (TIMP-1) in SF samples prospectively obtained from the same patient at different time intervals after a cruciate ligament injury of the knee. Aggrecan fragment concentrations were determined by dye precipitation with Alcian Blue. Stromelysin-1 and TIMP-1 were analysed by immunoas

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Popular Abstract in Swedish Deformerbara speglar som används i teleskop är förhållandevis små med en diameter på 10-30 cm, med undantag av ett fåtal. Den största deformerbara spegeln som är integrerad i ett teleskop idag, har en diameter på 911 mm och återfinns i Large Binocular Telescope. I designen för E-ELT har en deformerbar spegel med en diameter på dryga 2 m inkluderats och GMT har ett antal

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Based on a case study of a telecom company’s transition towards more software value in their products, we describe and discuss SCM issues related to when traditional manufacturers go from a “hardware focus” to a mixed product configuration. Although software supply chain is not much discussed in logistics, it seems that logistics/SCM frameworks also fit many software supply issues. A specific soft

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Background How many time's a word appear in a corpu's constitute's it's word frequency. Word frequency affect's memory in robust but puzzling way's. In free recall paradigm's high frequency (HF) word's are easier to recall than low frequency (LF) word's, in list's with homogenou's word frequencie's. If HF and LF word's are mixed together in a list thi's affect recall of HF word's negatively

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Within the field of emergency management and fire response, risk and quality are conceptualized to some degree in every response effort. Quality is viewed as a relatively new concept within the field of emergency management and fire response. Whereas, within this same field the concept of risk is more commonly discussed. In this paper, the commonalities between risk and quality are identified and

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A Dimple Jacket Heat Exchanger (DJHE) is designed for the Chemical Post-Processing Integrated Equipment (CPPIE) to enhance the heat transfer performance during chemical reaction, crystallization and drying processes. In this paper, a 3D model of a DJHE is established. Dynamic variation of temperature inside the DJHE is compared with experimental data to validate the accuracy of the numerical metho

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ObjectiveTo investigate the association between longitudinal changes in proton magnetic resonance spectroscopy (MRS) metabolites and amyloid pathology in individuals without dementia, and to explore the relationship between MRS and cognitive decline.MethodsIn this longitudinal multiple time point study (a subset of the Swedish BioFINDER), we included cognitively healthy participants, individuals w

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The development of multigene classifiers for cancer prognosis, treatment prediction, molecular subtypes or clinicopathological groups has been a cornerstone in transcriptomic analyses of human malignancies for nearly two decades. However, many reported classifiers are critically limited by different preprocessing needs like normalization and data centering. In response, a new breed of classifiers,

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Objective: The aim was to explore stem cell recipients’ perceptions of experiences of having a sibling donor from pretransplantation to one year afterwards in order to support their learning process.Methods: Ten adult recipients, five women and four men, with a mean age of 52 years (19-68 years) receiving stem cells from a sibling donor were included consecutively. We used a phenomenographic appro

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Purpose of this paper The purpose of this paper is to propose a framework for describing and analyzing misalignments in supply chain management, which relate to changes in supply chain structures, processes, and management components. Design/methodology/approach Based on the systems approach, a single-case study with embedded design including several embedded cases from the same supply chain was

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By using examples of European meetings with indigenous Mi‟kmaq in the Atlantic provinces of Canada in the early 17th century, I will show how the concept of wilderness was employed as a key metaphor for establishing the moral right and duty of Europeans to colonize the land, reorganizing the nomadic hunters in settled communities and remaking the mobile nature of the “savage” in the image of a cul

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A measurement is presented of the cross section for the production of a W boson with one or two jets, of which at least one must be a b-jet, in pp collisions at root s = 7 TeV. Production via top decay is not included in the signal definition. The measurement is based on 35 pb(-1) of data collected with the ATLAS detector at the LHC. The W + b-jet cross section is defined for jets reconstructed wi

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The responses to step and pulse transients with reactants have been simulated for conventional step-transient conditions at atmospheric pressure and pulsing under vacuum using a temporal analysis of products (TAP) reactor, respectively. Propene oxidation over an oxide catalyst with the participation of lattice oxygen was chosen as a model reaction. The mechanism comprises adsorption of the reactan

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During the 20 years since the first child was born in Sweden after in vitro fertilisation, clinical policy has changed. During the early 1990s, the clinics performing in vitro fertilisation and the National Board of Health and Welfare agreed to reduce the number of embryos transferred to the uterus during in vitro fertilisation from three to two. Here, we describe the changes in multiple birth rat

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Object. Cerebral vasospasm following subarachnoid hemorrhage (SAH) leads to reduced cerebral blood flow (CBF) and to cerebral ischemia, in some cases even producing infarction and long-term disability. The goal of the present study was to investigate the hypothesis that inhibition of neurokinin-1 receptors (NK1Rs) by administration of L-822429 blunts the decrease in CBF as well as cerebrovascular

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Background: Several studies have shown a higher mortality rate in patients with osteoporosis-related fractures of the hip and vertebrae. Method: In 1999, we did a long-term follow-up case-control mortality study of 253 patients, mean age 72 years, who had sustained a fracture of the surgical neck of the humerus in 1987. Results: We found a higher mortality in fracture patients giving at end point

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The epidemiology and costs of repair and rehabilitation of zone 11 flexor tendon injuries in 135 patients from the southern part of Sweden were analysed. The little finger was most frequently injured (43%), usually with a knife (46%), and 30% of the injuries were work related. Total median costs within the health-care sector for the injuries were SEK 48,500 (1 EURO = 9.23 SEK, 4/1/2002). Costs in