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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192314 hits

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Many children and adolescents with hearing impairment struggle to meet school demands. The difficulties can be traced to the characteristics of the hearing impairment, and to adverse consequences on language development, often overlooked in diagnostics and intervention. This thesis investigates the communicative ability of children and adolescents with bilateral sensorineural hearing impairment by

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Blood lead concentration (B-Pb), the main biomarker of lead exposure and risk, is curvi-linearily related to exposure. We assessed plasma lead (P-Pb) as a marker for both lead exposure and toxic effects. We examined claims that delta-aminolevulinic acid dehydratase genotype (ALAD) can modify lead toxicity. In 290 lead-exposed and 91 unexposed Chinese workers, we determined P-Pb, B-Pb, urinary lead

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Objective: There is growing evidence in the neuropsychological literature that growth hormone (GH) deficiency is associated with cognitive impairment. There is also evidence that this impairment may be ameliorated with GH replacement therapy. The current study assessed the nature and severity of cognitive impairment associated with growth hormone deficiency, as well as effect of GH replacement on

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A sample of 125 consecutive patients from a Swedish detoxification unit were followed up at five years. Register data on criminal behavior were retrieved for 99% of all subjects, including those who were deceased at follow-up, and 76% of living subjects were interviewed. A diagnosis of antisocial personality disorder (ASPD) at intake was associated with incarceration, continuous drug use, dependen

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Immunization of mice with type II collagen (CII) leads to collagen-induced arthritis (CIA), a model for rheumatoid arthritis. T cell recognition of CII is believed to be a critical step in CIA development. We have analyzed the T cell determinants on CII and the TCR used for their recognition, using twenty-nine T cell hybridomas derived from C3H.Q and DBA/1 mice immunized with rat CII. All hybridom

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The involvement of researchers in the policy process and policy-makers in research is little studied, particularly in developing countries. In 1993, the Lao National Drug Policy (NDP) was endorsed in a consultative process involving many stakeholders. Lao People's Democratic Republic is a poor country in South East Asia. Five pilot provinces were selected for implementation of the policy, which ha

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Popular Abstract in Swedish Små, trådlösa och portabla apparater utgör idag en stor del av vår uppkopplade värld. Under det senaste decenniet har dock flera teknologiska framsteg lett mot en utveckling där allt från maskiner till kläder kommunicerar med varandra. Detta brukar kallas för "sakernas internet" och uppskattas involvera 50 miljarder enheter år 2020. Genom att förse dessa enheter med småThe modern small devices of today require cheap low power radio frequency (RF) transceivers that can provide reliable connectivity at all times. In an RF transceiver, the analog-to-digital converter (ADC) is one of the most important parts and it is also one of the main power consumers. There are several architectures for implementing an ADC, but in the last decade, continuous-time Delta-Sigma mod

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Manufacturing corporations sometimes use corporate-internal procedures to evaluate and monitor the ergonomic status of the workplace. This article describes an industrial case study in the Swedish automotive sector, where an internally developed evaluation procedure was compared with a procedure based on a Swedish national standard provision. It was found that the national standard procedure tende

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In Kenya, the government is promoting high-value and drought resistant crop varieties in an effort to reduce poverty in rural areas. Sugar beet is one such crop. This study was conducted with two objectives: 1) to assess the opportunities and challenges for sugar beet cultivation and adoption in the Nyandarua district of Kenya and 2) to assess whether sugar beet adoption can offer an opportunity f

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BACKGROUND: Post-partum hemorrhage (PPH) is the major cause of maternal mortality in Ghana and worldwide. Active management of the third stage of labor (AMTSL) is a globally recommended three-step method that in clinical trials has been proven effective in prevention of PPH. The AMTSL guidelines were introduced in 2003, modified in 2006, and has been part of the national guidelines in Ghana since

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Development of B-lymphoid cells in the bone marrow is a process under strict control of a hierarchy of transcription factors. To understand the development of a B-lymphoid-restricted functional network of transcription factors, we have investigated the cell autonomous role of the transcription factor EBF1 in early B cell development. This revealed that even though transplanted EBF1-deficient fetal

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AIM: Schoolchildren aged 10-11 with a family history of premature coronary artery disease (CAD), were examined in order to identify children with genetically determined dyslipidemias and a combination of risk factors. METHODS: A total of 4000 questionnaires were distributed by the school; 55% of the families answered and returned the questionnaire. Blood lipids, apolipoprotein B, and Lp(a) lipopro

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The Autocapture algorithm enables automatic capture verification on a beat-by-beat basis by recognizing the evoked response signal following each pacemaker stimulus. The algorithm intends to increase patient safety while decreasing energy consumption. However, the occurrence of fusion beats, particularly during dual chamber pacing, may limit the energy saving effect of Autocapture. The aim of this

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The four known species of Tarnania Tuomikoski are reviewed, viz. T dziedzickii (Edwards, 1941), T. fenestralis (Meigen, 1818), T. nemoralis (Edwards, 1941), and T. tarnanii (Dziedzicki, 1910). Males and females are re-described, photographed and their terminalia figured. An attempt is made to homologize and name specific substructures of the male gonostylus, widely recognizable within the tribe Ex

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Orthostatic hypotension (OH) is a relatively common heterogenous and multifactorial disorder, traditionally classified as neurogenic (less common but often more severe), or non-neurogenic (more common, with no direct signs of autonomic nervous system disease). The different clinical variants of orthostatic intolerance include initial, classical and delayed OH as well as postural tachycardia syndro

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The usefulness of dietary strategies against cardiometabolic risk is increasingly being acknowledged. Legumes and whole grains can modulate risk markers associated with cardiometabolic diseases, but their possible additive/synergistic actions are unknown. The objective of the present study was to assess, in healthy subjects, the effect of a diet including specific whole-grain barley products and l