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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192327 hits

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The width of the Higgs boson is a quantity that cannot be measured directly from the on-shell Higgs peak; it would have to be measured indirectly. In 2013, Caola and Melnikov developed a method to determine the Higgs width by using off-shell and on-shell cross-sections and applying the narrow-width approximation. In this thesis, we will use the indirect method of finding the Higgs width for the pr

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Financial institutions and VAT are often like oil and water. If a financial institution is considering centralizing an activity in a certain jurisdiction, non-recoverable VAT could pose a serious problem. In addition to that, ambiguous judgments of the European Court of Justice have contributed to this issue. As of now, even services carried out within the same legal entity may trigger non-recov

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Notice taken towards the position of philanthropy in sub-Saharan Africa has increased in the lastdecade. Increasing amounts of private wealth, charity and philanthropy initiatives are changing the landscape earlier characterised by traditional forms of philanthropy that have been practised between people and communities. This study explored the central conversation around philanthropy in sub-Sahar

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Tropiska skogar utsätts för mer intensiva och frekventa torkor. Torkor påverkar tillväxt och kollagring i skogen, samt ökar risken för trädödlighet. Det finns flera hypoteser om mekanismerna bakom dödlighet under torka. Två av de vanligaste är något som kallas kolsvält och kavitation. Det är oklart vilken av dessa två mekanismer som inträffar först i tropiska träd under långvarig torka. ExperimentTropical forests experience more intense and frequent droughts. Droughts affect mortality in trees, growth rate and carbon storage in the forest. There are several hypotheses of the mechanisms behind tree mortality during drought. Two of the most common ones are carbon starvation and hydraulic failure. It is unclear which of these mechanisms occur first in tropical trees during long term drought.

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Conflict-related sexual violence against men occurs more frequently than often assumed, yet academic research and policy papers from international organizations tend to overlook male victims. The purpose of this study is to contribute to this limited knowledge by analyzing the effects of conflict-related sexual violence against men through a case study of the Democratic Republic of the Congo, a co

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This chapter explores the level and characteristics of the entrepreneurial activities of young people living in one such area, Bwaise, which is located on the outskirts of Kampala. Drawing on a participatory research methodology, it examines why and how young people establish businesses in a difficult urban environment and the range of challenges they face related to resource scarcity and inadequa

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This paper presents estimates of the level of per capita GDP and of the distribution of income of preindustrial Poland. This is based on a reconstruction of a social table of the Voivodeship of Cracow for 1578. Our evidence indicates that income in Poland was distributed more equally than in contemporary Holland. However, the extraction rate in the Voivodeship was much higher than in the North Sea

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Objective: To outline perceived associations between various sex hormones and risk markers for cardiovascular disease in middle-aged women, with an emphasis on features of the metabolic syndrome (MS). Design: Cross-sectional analysis. Setting: Women's Health in the Lund Area Study. Patient(s): Population-based cohort. Intervention(s): A generic questionnaire, physical examinations, and laboratory

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Decomposition of litter is a key biochemical process that regulates the rate and magnitude of CO2 fluxes from biosphere to atmosphere and determines soil nutrient availability. Although several studies have shown that plant litter decomposition accelerated in their native compared to a foreign environment, that is, a home-field advantage (HFA) for litter degradation, to date HFA has only been cons

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In this paper I address two concerns with Kelly Trogdon’s grounding mechanism view, i.e. the idea that metaphysical explanation can be modeled on causal-mechanical explanation. The first concern threatens to undermine the unity that grounding-mechanical explanations imposes on metaphysical explanation; and the second concern requires the grounding mechanic to put forth a formal condition on ground

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Environmentally friendly tin (Sn)-based metallic halide perovskites suffer from oxidation and morphological issues. Here, we demonstrate the composition engineering of Pb-Sn-alloyed two-dimensional (2D) Ruddlesden-Popper perovskites, (BA)2(MA)3Pb4-xSnxI13, for efficient and stable solar cell applications. Smooth thin films with high surface coverage are readily formed without using any additive ow

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An experimental study of subcooled flow boiling in a high-aspect-ratio, one-sided heating rectangular mini-gap channel was conducted using deionized water. The local heat transfer coefficient, onset of nucleate boiling (ONB), and flow pattern of subcooled boiling were investigated. The influence of heat flux and mass flux were studied with the aid of a high-speed camera. The bubbles were generated

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A reliable phylogenetic reconstruction of the evolutionary history of contemporary species depends on a robust identification of the universal common ancestor (UCA) at the root of the Tree of Life (ToL). That root polarizes the tree so that the evolutionary succession of ancestors to descendants is discernable. In effect, the root determines the branching order and the direction of character evolu

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Background: There is a demand for a flexible and individually tailored patient education to meet patients' specific needs and priorities, but this area has seldom been studied in patients with spondyloarthritis (SpA), a family of inflammatory rheumatic diseases. The aim of the present study was to identify needs and priorities in patient education in patients with SpA. A second aim was to investig

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The results from a round-robin study in which practicing fire safety engineers simulated the same scenario are presented in this paper. The simulation task included the simulation of an 800 mm heptane pool in a three-room apartment. The participants, representing eight Swedish consultancy firms, simulated the well-specified scenario with FDS 5. The participants received information about the build

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Background: The solute carrier family 30 member 8 gene (SLC30A8) encodes a zinc transporter in the pancreatic beta cells and the major C-allele of a missense variant (rs13266634; C/T; R325W) in SLC30A8 is associated with an increased risk of type 2 diabetes (T2D). We hypothesized that the association between zinc intake and T2D may be modified by the SLC30A8 genotype. Results: We carried out a pro

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Purpose: Current clinical parameters do not stratify indolent from aggressive prostate cancer. Aggressive prostate cancer, defined by the progression from localized disease to metastasis, is responsible for the majority of prostate cancer–associated mortality. Recent gene expression profiling has proven successful in predicting the outcome of prostate cancer patients; however, they have yet to pro

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Introduction: Lung cancer, a common malignancy and cause of cancer-related deaths, is strongly linked to several environmental exposures, and thus primarily affects the elderly. Formerly a man's disease, its incidence is rising among women, and lung cancer is now more common in women than men in Sweden. Women are particularly over-represented among young patients. While overall cancer mortality in