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We here discuss the potential theranostic nanomedicine application of an innovative formulation consisting of monoolein-based nanoparticles with a two-dimensional hexagonal inner structure stabilized in water using a mixture of PEO132-PPO50-PEO132 block copolymers with and without conjugated folate for targeting. The proposed tumor-cell targeted formulation was shown to be able to simultaneously h
Att utveckla ett strukturerat samverkansarbete Diskussionsunderlag och orientering SAMHÄLLSVETENSKAPLIGA FAKULTETEN | LUNDS UNIVERSITET Innehåll Förord..........................................................................................5 Varför denna skrift?...................................................................6 Hur kan den här skriften användas?..................................
https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2021-01/samverkansbroschyr_a5.pdf - 2026-07-18
Marine protected areas (MPAs) are being created around the world as the concern on species and habitats preservation is growing. A widespread concern related to the important lack of regulation and effective conservation measures has been raised, calling the attention to the importance of no-take areas within MPA’s. To justify more restrictive management decisions, it is essential to collect data
Monte Carlo simulations of linear polyelectrolytes together with explicit ions have been performed in a spherical cell model to study conformational changes and activity coefficients in relation to the isoionic dilution method used in viscosity measurements. The results show that it is possible to define an effective ionic strength that will keep the average chain conformation constant on isoionic
In 2018, the strategy for Sweden’s National Forest Program emphasized the Swedish forests as green gold. A peculiar formulation that I in this study trace to the roots of the existing Forestry Act. Directly I deal with the question: how has the forest been represented in the Swedish forest policy shift of 1993? The overarching question is complemented by several questions included in the critical
According to the World Health Organization (WHO), antibiotic resistance is a serious threat to our society. Infections with multi-resistant bacteria are causing increased mortality and social costs. Few new drugs are in the pipeline and no prospective of significantly improving the situation seems to be present. Sialic acids are a wide family of acidic sugars found in the terminal position of gly
The covid-19 related health crisis has marked a revolution in the history of remote work. New venture teams (NVTs) are being forced or recommended to pursue their new venture remotely and digitally and are likely to encounter obstacles. Therefore, having to deal with remote and virtual teamwork is critical to understand the reasoning behind operating a new venture. This virtual teamwork partly dep
Human immunodeficiency virus type 1 (HIV-1) rapidly evolves during disease progression. This study aimed to explore the intrahost diversity, evolutionary rate, molecular properties, and co-receptor tropism of HIV-1 in relation to disease progression in an occupational cohort of police officers from Guinea-Bissau, where the HIV-1 circulating recombinant form CRF02_AG predominated. The study partici
Introduction: Many individuals with Alzheimer’s disease (AD) live alone, and this figure is expected to increase. This study aimed to describe the cognitive and functional abilities of solitary-living AD patients, and the potential predictors of their usage of community-based services. Methods: This 3-year, prospective, multicenter study included 1,021 participants with mild-to-moderate AD (Mini-M
Context:In clinical practice, the safety profile of GH replacement therapy for GH-deficient adults compared with no replacement therapy is unknown.Objective:The objective of this study was to compare adverse events (AEs) in GH-deficient adults who were GH-treated with those in GH-deficient adults who did not receive GH replacement.Design and Setting:This was a prospective observational study in th
MSH2 rearrangements are involved in approximately 10% of hereditary non,polyposis colorectal cancer (HNPCC) families, and in most of the rearrangements, exon I is deleted. We scanned by quantitative multiplex polymerase chain reaction (PCR) of short fluorescent fragments (QMPSF) 200 kb of genomic sequences upstream of the MSH2 transcription initiation site in 21 HNPCC families with exon I deletion
ASHEIM B. T., LAWTON SMITH H. and OUGHTON C. Regional innovation systems: theory, empirics and policy, Regional Studies. Interest in regional innovation systems has grown significantly over the past three decades driven partly by advances in theoretical analysis, partly by the growing interest in innovation as a source of competitive advantage, and partly by the need for new policies to address re
We used three animal models of rats for rheumatoid arthritis (RA) in this study. Firstly, We found that CXI induced arthritis (CXIIA) is associated with the RT1 f haplotype and follows a chronic disease course affecting peripheral joints with both progression and relapses. The main difference of pathological changes in CXIIA rats against rats with CIIIA was a larger number of infiltrating lymphocy
Subjective quality of life (SQOL) is an important outcome in the treatment of patients with schizophrenia. However, there is only limited evidence on factors influencing SQOL, and little is known about whether the same factors influence SQOL in patients with schizophrenia and other mental disorders. This study aimed to identify the factors associated with SQOL and test whether these factors are eq
Objective: This study explores the effect of voice quality and competing speaker/-s on children’s performance in a passage comprehension task. Furthermore, it explores the interaction between passage comprehension and cognitive functioning. Methods: Forty-nine children (27 girls and 22 boys) with normal hearing (aged 7–12 years) participated. Passage comprehension was tested in six different liste
Context. The radial metallicity distribution in the Galactic thin disc represents a crucial constraint for modelling disc formation and evolution. Open star clusters allow us to derive both the radial metallicity distribution and its evolution over time. Aims. In this paper we perform the first investigation of the present-day radial metallicity distribution based on [Fe/H] determinations in late
