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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192346 hits

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We investigate the formation of self-bound quantum droplets in a one-dimensional binary mixture of bosonic atoms, applying the method of numerical diagonalization of the full Hamiltonian. The excitation spectra and ground-state pair correlations signal the formation of a few-boson droplet when crossing the region of critical interspecies interactions. The self-binding affects the rotational excita

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The History of African Development – published by the African Economic History Network (AEHN) – aims to draw experts in the field of African History, Economics and African Development Studies together around an open access textbook. The textbook is primarily intended for teachers/lecturers and undergraduate students, at African universities, but also for an interested wider public audience. The AE

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Morpho-taxonomic studies of cetrarioid lichens from India recorded 46 species representing Cetraria, Melanelia, Nephromopsis, and Platismatia. Nephromopsis awasthii is described as new to science; and Cetraria endochrysea, C. sinensis, Melanelia agnata, Nephromopsis ciliaris, N. morrisonicola, N. pseudocomplicata, N. pseudoweberi, N. rugosa, N. weii, and N. yunnanensis are reported for the first tMorpho-taxonomic studies of cetrarioid lichens from India recorded 46 species representing Cetraria, Melanelia, Nephromopsis, and Platismatia. Nephromopsis awasthii is described as new to science; and Cetraria endochrysea, C. sinensis, Melanelia agnata, Nephromopsis ciliaris, N. morrisonicola, N. pseudocomplicata, N. pseudoweberi, N. rugosa, N. weii, and N. yunnanensis are reported for the first t

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This work investigates the impact of the magnet segmentation on the continuous performance of an interior permanent magnet synchronous machine of a battery electric vehicle. Electromagnetic and thermal simulations, as well as thermal laboratory experiments are performed for the solid magnet reference design and the segmented magnet variant, and the results are compared, in order to verify the impa

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Background: The aim of the present study was to investigate the incidence and hallmarks of long-term survivors of recurrent ovarian carcinoma (LTSROC) in a large-scale retrospective cohort of patients from a multicenter study group. Methods: We performed a regional multicenter retrospective study between January 1986 and September 2021 using clinical data collected under the central pathological r

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Human PBL from vaccinated healthy blood donors, which was transplanted i.p. into mice with severe combined immunodeficiency (SCID), exhibited an Ag-dependent humoral Ir against tetanus toxoid. This Ir was dose dependent and was completely abrogated by immunizing with large amounts of Ag, suggesting a high dose tolerization of the B cells. A dose-dependent selection of specific, high affinity B clo

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BACKGROUND: Insulin resistance was found in some but not in all previous studies of non-diabetic first degree relatives of Type 2 diabetic patients. Small study groups, ethnic differences and/or non-optimal techniques may explain the conflicting results. AIM: To study the impact of a family history of Type 2 diabetes on insulin action in a large group of non-diabetic Europeans using the 'gold stan

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Little is known about the nature of post mortem degradation of proteins and peptides on a global level, the so-called degradome. This is especially true for non-neural tissues. Degradome properties in relation to sampling procedures on different tissues are of great importance for the studies of for instance post translational modifications and/or the establishment of clinical biobanks. Here, snap

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Urokinase plasminogen activator (uPA) is involved in the activation of different proteases which participate in the degradation of extracellular matrix, thereby enhancing the invasive capacity of tumour cells. uPA has been shown to be of prognostic importance in breast cancer. We have analysed uPA with a new luminometric immunoassay (LIA), applicable in cytosol samples routinely used for oestrogen

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Semantic memory access has been characterized as abnormal in schizophrenia, but findings concerning automatic spreading activation at short stimulus onset asynchronies (SOA) have been inconsistent. Using the N400 as an indicator of semantic priming, a recent study (Mathalon, Faustman, & Ford, 2002) found evidence of hyperpriming in schizophrenic patients in a picture verification task. The pre

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Some non-Western immigrant groups in Europe have elevated risk of psychosis relative to native-born. It is hypothesized that neighborhood ethnic density moderates this risk. Immigration to Sweden has increased substantially recently, particularly from the Middle East. This study examined the relationship between neighborhood ethnic density (i.e., living in an immigrant enclave) and risk of psychot

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The aim of this study was to analyse effects of a comprehensive continuum of care (intervention group) on frail older persons' life satisfaction, as compared to those receiving usual care (control group). The intervention included geriatric assessment, case management, interprofessional collaboration, support for relatives and organising of care-planning meetings in older persons' own homes.

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The main concern about the technology for the production of hydrogen and transport fuels by biomass gasification is the presence of contaminants (H2S, tars, fly ash, alkali, and heavy metals, ammonia) that are poisonous for the catalysts used for upgrading the biomass-generated gas. The impact of the main contaminants on a Ni/MgAl(O) reforming catalyst was studied in a laboratory environment, by e

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BACKGROUND/PURPOSE: Cytokines are essential for the prevention of microbial infections. Total parenteral nutrition (TPN) in infancy is associated with an increased risk of infection, and this could be related to altered cytokine production. The aim of the study was to determine if cytokine production is altered in monocytes from surgical infants receiving TPN. METHODS: There were 3 study groups: (

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Micrometer-sized enzyme grids were fabricated on gold surfaces using a novel method based on a flow-through microdispenser. The method involves dispensing very small droplets of enzyme solution (similar to 100 pL) during the concomitant relative movement of a gold substrate with respect to the nozzle of a microdispenser, resulting in enzyme patterns with a line width of similar to 100 mum. Differe

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This paper analyzes the recently undertaken restructuring of the Ministry of Health in Uganda, which was carried out because the previous structure did not comply well with the decentralization framework or policy. The Ministry was put under pressure by higher political levels, supported by the donor community, to restructure. The paper describes the principles that were guiding this operation, an