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Pulmonary arterial hypertension (PAH) is a lethal condition where expansion of the vascular extracellular matrix contributes to increased pulmonary vascular resistance. Versican, a chondroitin sulfate proteoglycan, is known to accumulate in vascular lesions of PAH and hyaluronan and tenascin-C, binding partners of versican, are elevated in PAH. The specific distribution and localization of versica

The purpose of this study was to investigate how private and public actors in the institutional care of children and young people’s homes (HVB) market them self on the internet. In 1982 the new Swedish Social Law made it possible for private providers to establish the institution for institutional care of children and young people (HVB). Since then, the development within institutional care has ta

Hypoxic–ischaemic brain injury (HIBI) is the main causeof death and disability in patients who are comatose afterreturn of spontaneous circulation (ROSC) from cardiacarrest [1]. Te electroencephalogram (EEG) is a usefultool to assess the severity of HIBI and provide prognostic information. In addition, EEG can be used to diagnoseepileptiform activity in patients with suspected seizuresand monitor

This article addresses the obstacle avoidance problem for setpoint stabilization tasks in complex dynamic 2-D environments that go beyond conventional scenes with isolated convex obstacles. A combined motion planner and controller is proposed that integrates the favorable convergence characteristics of closed-form motion planning techniques with the intuitive representation of system constraints t

In "Intentional action and side-effects in ordinary language” (2003), Joshua Knobe reported an asymmetry in test subjects’ responses to a question about intentionality: subjects are more likely to judge that a side effect of an agent’s intended action is intentional if they think the side effect is morally bad than if they think it is morally good. This result has been taken to suggest that the co

This study explores the impact academic teachers’ writing of a teaching portfolio can have on their professional learning. Through an open-ended questionnaire, 26 academics from three faculties reported on insights, effects on teaching practice, and effects on collegial exchange that the portfolio writing entailed. We discuss how the experienced impact relates to the three competence levels excell

Populärvetenskaplig sammanfattning(Summary in Swedish)Hjärnskada som orsakas av olyckor är en vanlig orsak till både handikapp och död bland vuxna. För 30 år sedan var majoriteten av de som drabbades yngre eller väldigt gamla. Ålderssammansättningen av de som drabbas har skiftat under de senaste 20 åren och nu är det ungefär lika vanligt i alla åldrar. Dessutom är den vanligaste olycksorsaken inte

Large eddy simulations (LES) and experiments (planar laser-induced fluorescence of the hydroxyl radical (OH-PLIF) and pressure transducer) have been carried out on a gas turbine burner fitted to an atmospheric combustion rig. This burner, from the Siemens SGT-800 gas turbine, is a low NOx, partially premixed burner, where preheat air temperature, flame temperature, and pressure drop across the bur

Det relativt lugna området bakom barriärö är en fördelaktig plats för hamn trots att navigationen genom själva inloppet kan vara utmanande. Olika åtgärder såsom muddring eller kuststrukturer kan vara nöd-vändiga för att säkerställa det önskade vattendjupet för en säker navigering. Island som är en önation är beroende av tillförlitliga navigeringsvägar som förbinder hamnar med havet. DThe relatively calm area behind barrier island are favored locations for harbors even though the navigation through the inlet itself can be challenging. Different measures like dredging or coastal structures might be necessary to ensure the desired water depth to maintain a safe navigation. Iceland as an island country depends strongly on reliable navigational routes connecting harbors to the ocea

Synucleinopthies are neurodegenerative diseases characterised by the formation of α-synuclein-rich intracellular inclusions in neurons and glia. Traditionally, animalmodels and immortalized cell lines have been used to investigate why and how theseinclusions form, and how they impact on cellular function. Recent advances incellular reprogramming and directed differentiation have enabled the genera