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The early B cell factor (EBF) is a transcription factor shown crucial for the development of B lymphocytes. The protein is expressed from the earliest stages of B cell development until the mature B cell stage, but the control elements responsible for the regulation of the gene are unknown. In this study, we report of the identification of a promoter region flanking the EBF gene. Several transcrip
Sensitizing capacities and cross-reactivity patterns of some diisocyanates and amines using the guinea-pig maximization test. Can p-phenylenediamine be used as a marker for diisocyanate contact allergy?
BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors
Protein S deficiency is a known risk factor for thrombosis. The coexistence of phenotypic type I (reduction in total and free antigen) and type III (reduction in free antigen only) protein S deficiencies in 14 of 18 families was recently reported. We investigated the cause of this phenotypic variation in the largest of these families (122 family members, including 44 affected individuals) using bo
The integrated dynamic ecosystem models SAFE and ForSAFEVEG were used to estimate critical loads for nitrogen using different chemical and biological criteria, and attempting to account for possible effects of climate change. The study is based on a model application on a set of 640 sites earlier used for critical loads assessments in Sweden, focusing on the ecological effect of nitrogen pollution
Purpose: Ocular coherence tomography (OCT) biomarkers have previously been able to predict low visual acuity (VA). The purpose of this study was to identify other OCT predictors for a final VA ≤35 and risk factors for macular atrophy (MA) in eyes with neovascular age-related macular degeneration (nAMD). Methods: This retrospective observational study included 107 treatment naïve nAMD eyes who init
Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers OR I G I N A L AR T I C L E Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers Bobbie-Jo M. Webb-Robertson1,2 | Lisa M. Bramer3 | Bryan A. Stanfill3 | Sarah M. Reehl3 | Ernesto S. Nakayasu1 | Thomas O. Met
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-06/121_MP193_Webb-Robertson_JDiabetes_2020%20(2).pdf - 2026-07-09
Microsoft Word - Handledning_2015_för distribution.doc Läs detta noga! Begrunda & behåll för framtida rådgivning & konsultation! STUDENTHANDLEDNING Information & regler för studenter vid KONSTHÖGSKOLAN I MALMÖ LUNDS UNIVERSITET läsåret 2015/2016 2 VÄLKOMMEN TILL KONSTHÖGSKOLAN I MALMÖ! Vår postadress är: Konsthögskolan i Malmö Box 4035 203 11 Malmö Besöks-/leveransadress: Föreningsgatan 42 211 52
https://www.khm.lu.se/sites/khm.lu.se/files/handledning_2015.pdf - 2026-07-09
Background: The aim of this study was to clarify the possible causal associations between education phenotypes and non-fatal suicide attempts. In particular, we evaluated the roles of academic achievement (school grades), cognitive performance (IQ), and educational attainment (education level). Methods: Based on longitudinal Swedish registry data, we included 2,335,763 individuals (48.7% female) w
• Misdiagnosed and maltreated scaphoid fractures filed to the Swedish National Patient Insurance Company (LÖF) 2011–2018 were analyzed in terms of complications and costs for society. All filed claims are database-registered (altogether 200 000 claims since 2000). This database was assessed in June 2019 through injury ICD10-SWE-diagnoses. Demographics, complications, complaints, corrective surgeri
Background: Cleft lip with cleft palate (CLP) is a congenital condition that affects both the oral cavity and the lips. This study estimated the prevalence and mortality of CLP using surveillance data collected from birth defect registries around the world. Methods: Data from 22 population- and hospital-based surveillance programs affiliated with the International Clearinghouse for Birth Defects S
Background: Despite being the gold standard of research to determine effectiveness, randomised controlled trials (RCTs) often struggle with participant recruitment, engagement and retention. These issues may be exacerbated when recruiting vulnerable populations, such as participants with mental health issues. We aimed to update understanding of the scope of these problems in trials of health techn
Nanoplastics have been proven to induce toxicity in diverse organisms, yet their effect on soil microbes like bacteria and fungi remains largely unexplored. In this paper, we used micro-engineered soil models to investigate the effect of polystyrene (PS) nanospheres on Pseudomonas putida and Coprinopsis cinerea. Specifically, we explored the effects of increasing concentrations of 60 nm carboxylat
The hippocampus is a primary region affected in Alzheimer's disease (AD). Because AD postmortem brain tissue is not available prior to symptomatic stage, we lack understanding of early cellular pathogenic mechanisms. To address this issue, we examined the cellular origin and progression of AD pathogenesis by comparing patient-based model systems including iPSC-derived brain cells transplanted into
This paper surveys Nordic historic studies on the distribution of income to highlight similarities and differences between Denmark, Finland, Norway, and Sweden in the evolution of income concentration and income inequality over more than 140 years. Our descriptive analysis allows for a decomposition where we identify the contribution of the income share of the richest 1 per cent and the distributi
Background: Postoperative management after surgery for perforated peptic ulcer is still burdened by old traditions. All available data for fast-track recovery in this setting are either very unspecific or underpowered. The aim of this study was to evaluate fast-track recovery in this diagnosis-specific context in a larger sample. Methods: Electronic data sources were searched. Eligible studies wer
Background: Alzheimer’s disease (AD) is a common, complex and multifactorial disease that may require screening across multiple routes of referral to enable early detection and subsequent future implementation of tailored interventions. Blood- and eye-based biomarkers show promise as low-cost, scalable and patient-friendly tools for early AD detection given their ability to provide information on
The Swedish Quality Registry for Pain rehabilitation (SQRP) is a well-established clinical registry for adult patients with complex chronic pain conditions. SQRP registers patient-reported outcome measures from a majority of specialist chronic pain units/departments in Sweden. Up to four International Classification of Diseases version 10 (ICD-10) diagnoses can be registered in SQRP. The aim of th
Accurate eye tracking is crucial for gaze-dependent research, but calibrating eye trackers in subjects who cannot follow instructions, such as human infants and nonhuman primates, presents a challenge. Traditional calibration methods rely on verbal instructions, which are ineffective for these populations. To address this, researchers often use attention-grabbing stimuli in known locations; howeve
Climate change is rapidly altering the Arctic environment. Although long-term environmental observations have been made at a few locations in the Arctic, the incomplete coverage from ground stations is a main limitation to observations in these remote areas. Here we present a wind and sun powered multi-purpose mobile observatory (ARC-MO) that enables near real time measurements of air, ice, land,
