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Focusing on three initiatives of the United Nations Framework Convention on Climate Change (UNFCCC) Secretariat – the Momentum for Change Initiative, the Lima–Paris Action Agenda, and the Non-state Actor Zone for Climate Action – this chapter studies how an international environmental bureaucracy can evolve from a low-key and servant-like secretariat to an actor in its own right. It argues that in

Introduction: The American Association of Neurologic Surgeons guidelines on the management of traumatic spinal cord injury (SCI), updated in 2013, focus on spinal cord perfusion, early decompressive surgery, and venous thromboembolism (VTE) prophylaxis to improve neurological outcome. Research question: How neurocritical care and initial management have changed with the implementation of updated m

The axillary lymph node status remains an important prognostic factor in breast cancer, and nodal staging using sentinel lymph node biopsy (SLNB) is routine. Randomized clinical trials provide evidence supporting de-escalation of axillary surgery and omission of SLNB in patients at low risk. However, identifying sentinel lymph node macrometastases (macro-SLNMs) is crucial for planning treatment ta

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Phasor measurement signals are used as only input to a wide-area power system stabilizer to increase interarea mode damping of the Icelandic system. Modal analysis and time simulations of a detailed model show that frequency difference as PSS input gives a damping improvement that is robust to drastic changes in system topology. Field data from phasor measurement units indicate high signal quality

Introduction: Home oxygen therapy is one of the few interventions that can improve survival in patients with chronic obstructive pulmonary disease (COPD) when administered appropriately, although it may cause side effects and be an unnecessary burden for some patients. Areas covered: This narrative review summarizes the current literature on the assessment of hypoxemia, different types of home oxy

Background: COPD management is guided by the respiratory symptom burden, assessed using the modified Medical Research Council (mMRC) scale, the COPD Assessment Test (CAT), or both. Research Question: What are the abilities of mMRC and CAT to detect abnormally high exertional breathlessness on incremental cardiopulmonary cycle exercise testing (CPET) in people with COPD? Study Design and Methods: A

BACKGROUND: Long-term oxygen therapy (LTOT) improves survival in patients with chronic severe resting hypoxaemia, but effects on hospitalisation are unknown. This study evaluated the potential impact of starting LTOT on acute exacerbation and hospital burden in patients with chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD) and pulmonary hypertension (PH).METHODS: Longi

The paper provides an overview and preliminary results from ongoing research with the aim to evolve cross-laminated timber (CLT) into the next generation of Tailored Laminated Timber (TLT). This is done by exploring innovative concepts that optimize the mechanical performance, while simultaneously ensuring adherence to circular economy principles. The current study aims at investigating the potent

Artificial intelligence (AI) is increasingly being discussed at the international level, with a particular focus on its potential to help achieve the Sustainable Development Goals (SDGs). The Global Digital Compact, adopted at the Summit of the Future, calls for the establishment of international institutions to govern AI technologies. The impact of AI on sustainable development is a multifaceted