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In this paper we derive the finite-sample distribution of the estimated weights of the tangency portfolio when both the population and the sample covariance matrices are singular. These results are used in the derivation of a statistical test on the weights of the tangency portfolio where the distribution of the test statistic is obtained under both the null and alternative hypotheses. Moreover, w
Anxiety and stress-related disorders are highly prevalent and impede participation in life activities. Occupational therapists work extensively with people diagnosed with these disorders but the effectiveness of their interventions is unclear. A systematic search strategy identified 19 papers describing 13 studies. Studies varied in methodology, intervention type, and theory base. The results show
The direct involvement of S100 calcium-binding proteins A8 (S100A8) and A9 (S100A9) in numerous human diseases have been discovered more than 20 years ago, and they have ever since emerged as a very potent biomarker. Increased levels of S100A8 and S100A9 have been found in inflammation and various cancers. As complexes, they become crucial danger signals and act as endogenous activators of TLR4 (T
Den inre strukturen och vävnaden hos ben ger information om livsstil hos nutida och utdöda djur. Mosasaurier (familj Mosasauridae) är en grupp sekundärt anpassade marina reptiler som utvecklades och spred sig under sen krita, vilket resulterade i en kropp väl anpassad för marina miljöer. Marina anpassningar hos den här gruppen kan observeras på olika nivåer i skelettanatomin, exempelvis mikrostrukThe inner bone architecture and histology provide information about life history traits of extant as well as extinct animals. Mosasaurs (family Mosasauridae) are a group of secondarily adapted marine squamates that radiated in the Late Cretaceous, resulting in the evolution of a body plan adapted for pelagic habitats. Specialisa-tions in this group can be observed at different levels of skeletal a
Cetuximab is an epidermal growth factor receptor (EGFR)-targeting drug that has shown effects in head and neck squamous cell carcinoma (HNSCC). The effects are, however, small and have mainly been proven in a subset of patients, and the cost-effectiveness has been questioned. For this reason, we need to know more about the basic mechanisms controlling the effect of EGFR signalling on tumour growth
The northern terrestrial net ecosystem carbon balance (NECB) is contingent on inputs from vegetation gross primary productivity (GPP) to offset the ecosystem respiration (R-eco) of carbon dioxide (CO2) and methane (CH4) emissions, but an effective framework to monitor the regional Arctic NECB is lacking. We modified a terrestrial carbon flux (TCF) model developed for satellite remote sensing appli
Socioeconomic status could potentially impact on which type of rheumatic diagnosis a patient receives. We determined whether different socioeconomic status is a risk factor for being diagnosed with spondyloarthritis (SpA) or chronic pain. In a nested case-control study, we identified two sets of adult cases diagnosed with (i) SpA (n = 1,194) and (ii) chronic pain (n = 3,730) during 2010-2012 in Sk
Early exiting from the labor force and into disability pension (DP) represents a major social problem in Sweden and elsewhere. We examined how being asymmetric (A-SGA) or symmetric (S-SGA) small for gestational age predicts transitioning into DP. We analyzed a longitudinal sample of 8125 men and women from the Stockholm Birth Cohort (SBC), born in 1953 and not on DP in 1990. The SBC consists of da
Aims: To analyse dosimetric and clinical predictors for acute and late gastrointestinal toxicity following chemoradiotherapy of anal cancer. Materials and methods: Consecutive patients with locally advanced (T2 ≥4 cm – T4 or N+) anal cancer were selected from an institutional database (n = 114). All received intensity-modulated radiotherapy with concomitant 5-fluorouracil and mitomycin C. Gastroin
Blodet bär med sig syre och näringsämnen som är vitala för vävnadens överlevnad, och därför är karakterisering av hjärnans blodförsörjning av stor betydelse. Blodflödet i kapillärerna kallas för perfusion. Vid MRI-baserad perfusionsmätning i hjärnan utnyttjas ofta signalförändringar orsakade av ett spårämne i blodet. Spårämnet kan antingen skapas internt genom märkning av det arteriella inflödet aDiffusion and perfusion MRI are valuable methods for investigating the microstructure and viability of tissue. One pure diffusion study was included in this thesis, with the purpose of studying microstructure and carrying out size estimations with the q-space diffusion imaging method. This is a method that has predominantly been explored with NMR spectrometers. In our study, a biological phantom c
Open access has established itself as an issue that researchers, universities, and various infrastructure providers, such as libraries and academic publishers, have to relate to. Commonly policies requiring open access are framed as expanding access to information and hence as being part of a democratization of society and knowledge production processes. However, there are also other aspects that
This study investigates temporal relationships between vegetation growth, rainfall, and soil moisture for six sites located in sub-Saharan and southern Africa for the period 2005-2009. Specifically, seasonal components of time series of Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) composites from the Moderate Resolution Imaging Spectroradiometer (MODIS) and hal
Pedagogisk portfölj130214 PEDAGOGISK PORTFÖLJ Marcus Knutagård 9 februari 2013 1 Kockumsgatan 6 211 42 Malmö 040-12 61 69 marcus.knutagard@soch.lu.se Från naiva teorier till konceptuell förändring 2 Innehållsförteckning Inledning ..................................................................................... 3 ”Var i raketen sitter det nya året?” ...........................................
https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/pp-marcus-knutagard.pdf - 2026-07-11
Se upp med oseriös open access! Lärdomar att hämta från Kalifornien Lovande enzym prövas Tusenkonstnär Lunds universitets magasin | Nr 3 | 2014 Mångsidig kemist fokuserar på nuet 2 LUM nr 3 | 2014 LUM nr 3 | 2014 3 Medeltida kristendom möter modern indiansk andlighet genom en ny foto utställning i Klosterkyrkan i Ystad. Bakom storbilderna av nordamerikan ska indianer och deras heliga platser, st
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-3-2014.pdf - 2026-07-11
Lum nr 4/08 LUM Lunds universitets magasin | Nr 4 | 2008 Antika gudar får nytt hem Nya enzym lovande mot folksjukdomar finns superrektorn? Ranking på gott och ont 2 LUM nr 4 | 2008 bysthållare LUM nr 4 | 2008 3 En underkropp här, ett huvud där och en överkropp lite vid sidan om. Det är lite si och så med värdighe- ten bland antikens gudar inför flyt- ten från Klassiska institutionen till Historisk
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-4-2008.pdf - 2026-07-11
LUM nr 9 - 2005 LUM Lunds universitets magasin | Nr 9 | 2005 STÄNDIGT NYFIKEN Koldioxidutsläpp i Gudruns spår Kvinnor blev ”bara” prodekaner 2 LUM NR 9 | 2005 LASERKOLLAR COLOSSEUM LUM NR 9 | 2005 3 Det var inte helt lätt för lundafors- karna att få tillstånd att göra mät- ningar på Colosseum, Italiens främ- sta kulturminne och högt på listan över tänkbara terroristmål. Men när tillståndet väl var
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-9-2005.pdf - 2026-07-11
