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Living labs and co-production are increasingly popular strategies for universities to address sustainability challenges and yet the links between them remain largely implicit. This paper discusses the potential of living labs to provide a holistic and iterative framework for the co-production of knowledge. The University Living Lab initiative was launched in 2012 to transform the University of Man

MOTIVATION: Gene expression-based multiclass prediction, such as tumor subtyping, is a non-trivial bioinformatic problem. Most classifier methods operate by comparing expression levels relative to other samples. Methods that base predictions on the expression pattern within a sample have been proposed as an alternative. As these methods are invariant to the cohort composition and can be applied to

Research have shown that the correct integration of daylight and electric lighting reduces the energy use in buildings, while improving visual comfort. Smart shading systems, especially those electrically controlled, play an important role to control solar radiation. Similarly, smart and dimmable/tunable lighting can help to adjust the artificial light to the real users' needs. This paper presents

Background: Pelvic exenteration for locally advanced rectal cancer (LARC) and locally recurrent rectal cancer (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes of exenteration over time.Methods: This was a multicentre retrospective study of patients who underwent exenteration for LARC and LRRC between 2004 and 2015. Su

Using a new sample environment, the two operando surface diagnostic techniques two-dimensional surface optical reflection (2D-SOR) and polarization-modulated infrared reflection–absorption spectroscopy (PM-IRRAS) have been combined with mass spectrometry (MS) to characterize a catalytic reaction. With both techniques integrated in a custom-built setup, we can correlate molecular information of the

The production of biopharmaceuticals so far has been based on batch processes that are robust and well-known, but very inefficient and inflexible, causing the products to be very expensive and process development to be slow and costly. The production of biopharmaceuticals is thus changing towards integrated continuous biomanufacturing (ICB) in order to reduce costs and increase flexibility in a co

We report on an optical investigation of the pyrolysis and photolysis of trimethylindium (TMIn) as a typical metalorganic precursor for functional nanowire growth, aiming at an in-depth understanding of the governing chemistry and optimization of aerosol-based (aerotaxy) and epitaxial growth processes. A flow reactor with special consideration given to optical access was built to provide the chemi

The Pythia event generator is used in several contexts to study hadron and lepton interactions, notably p p and p p ¯ collisions. In this article we extend the hadronic modelling to encompass the collision of a wide range of hadrons h with either a proton or a neutron, or with a simplified model of nuclear matter. To this end we model hp total and partial cross sections as a function of energy, an

Mutations in either mitochondrial DNA (mtDNA) or nuclear genes that encode mitochondrial proteins may lead to dysfunctional mitochondria, giving rise to mitochondrial diseases. Some mitochondrial myopathies, however, present without a known underlying cause. Interestingly, methylation of mtDNA has been associated with various clinical pathologies. The present study set out to assess whether mtDNA

A Soft X-ray free electron laser (FEL) for the MAX IV Laboratory is currently in the design phase and it will use the existing 3 GeV linac. Present stability limits in the RF and the photocathode laser will affect the performance of the FEL. One of the critical elements for the design of a FEL is to have an estimation on jitter effects of the accelerator parameters on the X-ray radiation. In this

Small- and medium-sized enterprises (SMEs) have inherent characteristics, which require specific solutions for improving the sustainability performance of their operations. The purpose of this paper is to increase the knowledge on barriers and enablers for the adoption of sustainable manufacturing by manufacturing SMEs and to provide insights into what enablers can be used to overcome existing bar

The alliance between the seemingly disparate Lebanese Christian party Free Patriotic Movement and the Shi’a organization Hezbollah has survived many local and regional upheavals since the signing of the memorandum of understanding (MoU) in February 2006. The pact was strengthened after the 2006 summer war and has stood for 15 years - despite political assassinations and low-intensity conflict in L

Although it is advocated that end-users are engaged in developing evidence-based injury prevention training to enhance the implementation, this rarely happens. The ‘Implementing injury Prevention training ROutines in TEams and Clubs in youth Team handball (I-PROTECT)’ uses an ecological participatory design incorporating the perspectives of multiple stakeholders throughout the project. Within the

For polarization-resolved reflection experiments such as ellipsometry, not only is high reflectivity in a wide spectral range required for mirrors but also the quality of their polarization response is important. Furthermore, for VUV ellipsometry, optimal angles of incidence at the sample are between 45° and 60° with respect to the surface normal. In the best case, a setup should even allow variab

BACKGROUND: Plasma biomarkers for Alzheimer's disease (AD) have broad potential as screening tools in primary care and disease-modifying trials. Detecting elevated amyloid-β (Aβ) pathology to support trial recruitment or initiating Aβ-targeting treatments would be of critical value. In this study, we aimed to examine the robustness of plasma biomarkers to detect elevated Aβ pathology at different

We prove Nehari s theorem for integral Hankel and Toeplitz operators on simple convex polytopes in several variables. A special case of the theorem, generalizing the boundedness criterion of the Hankel and Toeplitz operators on the Paley Wiener space, reads as follows. Let = (0, 1)d be a d-dimensional cube, and for a distribution f on 2, consider the Hankel operator f (g)(x) = λ f (x + y)g(y) dy,