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CASE-dagen 2026

Arrangerades 16 april 2026, kl. 9.15-16, LUX Aula, Helgonavägen 3 i Lund. Årets populärvetenskapliga konferens arrangerades i Lund tillsammans med CASE Intressentråd. Den här gången på temat “Mitt hem är min borg – om omsorg, trygghet och innovation för äldre”. Marianne Rundström, tidigare nyhetsankare på SVT, modererar föreläsningarna och paneldiskussionerna under dagen. MÅLGRUPPER för konferense

https://www.case.lu.se/casedagen - 2026-05-27

Kan akademin hjälpa industrin utveckla mer robusta grundvattenmodeller? En studie av moderna svenska industriframtagna grundvattenmodeller

Grundvattenmodellering används ofta av yrkesverksamma hydrogeologer för att ta fram predikt- ioner som ska fungera som underlag i beslutsfattandeprocesser. I Sverige finns det inga lagar som reglerar hur en grundvattenmodell ska utformas, och de kan se väldigt olika ut. Därför har syftet med detta arbete varit att under- söka svenska grundvattenmodeller skapade av industrin i beslutsändamål under Groundwater modeling is often employed by professional hydrogeologists to make predictions to be used by regulators in decision-making. In Sweden, there are no laws governing the way in which a groundwater model may be created or shaped, and therefore they may differ wildly from one another. Thus, the goal of this study has been to research Swedish groundwater models created by the industry during

Cumulative Wisdom or Compounding Complexity: The learning curve among serial acquirers. (Sweden)

This thesis investigates the performance dynamics of serial acquirers in the Swedish market, specifically focusing on their ability to realize cost synergies over time. Through an empirical analysis of Swedish firms engaging in mergers and acquisitions (M&A) between 2010 and 2019, we aimed to determine whether serial acquirers exhibit improved synergy realization in subsequent acquisitions com

Självkörande bilar i urbana miljöer - En studie med avseende på trafiksäkerhet

Until today, the performance of a motor vehicle has required the present of a human driver. With a human driver follow human factors. In recent years, more automatic functions have been implemented in new cars and self-driving cars at higher levels have begun to develop. This development limits the influence of the human factors. The purpose is with the thesis project, to investigate which problem

Analysis of HLA-A, -B and -DR Alleles as Risk Factors for One-Year Mortality in Heart Transplants Using Artificial Neural Networks

Hjärttransplantationer syftar till att rädda liv men kan även vara riskabla ingrepp. Det är mycket som kan gå fel. Det transplanterade hjärtat lider stor risk att avstötas i mottagarens kropp, och en mer detaljerad kunskap om faktorerna som påverkar avstötning har således möjligheten att rädda liv. Avstötning orsakas av att mottagarens immunförsvar känner av HLA-molekylerna, där HLA står för HumThe beneficial effects of HLA matching at the HLA-A, -B and -DR loci on recipient short- and long-term survival in heart transplants have been established in a number of studies. The objective of the present study was to evaluate the importance of individual HLA alleles at the HLA-A, -B and -DR loci as risk factors for recipient death within one year after transplant by using artificial neural net

A perspective on integrating digital pathology, proteomics, clinical data and AI analytics in cancer research

Nearly 40 % of individuals will be diagnosed with cancer in their lifetime, translating to an estimated 20 million new cases annually. Despite remarkable therapeutic advances, only 15–20 % of patients achieve durable responses to immunotherapy, and the high cost of treatment (illustrated by immune checkpoint inhibitors like pembrolizumab and nivolumab, totaling roughly $191,000 per year) remains a

Literary exploration as a resource for professional development : Junior doctors’ experiences of shared reading

Studies have shown positive health outcomes from shared reading (SR) for various patient groups. In this article, we explore whether this applies to doctors as well by studying the dynamics of SR sessions and a subsequent participant focus group. Four SR sessions, with one short story and one or two poems each, were held with medical interns working at Skåne University Hospital, Sweden. A reflexiv

Immune biomarkers for epilepsy in autism : indications of cytokine alterations in an exploratory cross-sectional pediatric study

BACKGROUND: Children with autism spectrum disorder (ASD) are at increased risk of epilepsy (EP), but distinguishing epileptic seizures from ASD-associated behavior remains a clinical challenge. Although previous studies have reported changes in peripheral immune markers in adults with EP, it remains unclear whether similar immune signatures are present in pediatric patients with both ASD and EP, a

Mapping the formation of reactive oxygen species (ROS) from combustion and traffic-related particulate air pollution

Traffic-related air pollution has severe implications for our health and stringent emission legislation is being enforced to traffic emissions, for example in the EU, USA, and China. With stricter emission legislation (next is EURO 7) and a rapid growth of battery electrical vehicles (BEVs) the combustion-derived pollutants emitted from the tailpipe are decreasing. However, heavier vehicles have r

ROS production of source-specific emissions from combustion, brake, tire and road wear

Comparison of ROS production of individual particle components from traffic-related sources can inform new health policies and emissions legislation. This work aims to quantify acellular ROS production and oxidative potential (OP) of such individual particle components from combustion, brake, tire, and road wear. Particle characteristics are probed to identify source-specific markers and improve t

Effect of a Detailed Family History of Melanoma on Risk for Other Tumors: A Cohort Study Based on the Nationwide Swedish Family-Cancer Database

Using the Swedish Family-Cancer Database, we assessed the effect of a detailed family history of melanoma on risk for other tumors (other than melanoma). Among 248,011 individuals with a family history of melanoma, 43,931 other tumors were diagnosed from 1958 to 2010. Standardized incidence ratios (SIRs) were calculated for other tumors in patients who had a family history of melanoma, as compared

A hybrid population of Willow Warblers in the Åland Archipelago

Differences in migratory behavior have been suggested to drive speciation, but the genetics underlying this process remain unknown. Identification and study of migratory divides can help us understand how differential migration can lead to reproductive isolation. Here, we genotyped Willow Warblers Phylloscopus trochilus, from the Åland islands, located in between the ranges of the differentially m

On the interactions between RNA and titrateable lipid layers : implications for RNA delivery with lipid nanoparticles

Characterising the interaction between cationic ionisable lipids (CIL) and nucleic acids (NAs) is key to understanding the process of RNA lipid nanoparticle (LNP) formation and release of NAs from LNPs. Here, we have used different surface techniques to reveal the effect of pH and NA type on the interaction with a model system of DOPC and the CIL DLin-MC3-DMA (MC3). At only 5% MC3, differences in

Dynamical arrest for globular proteins with patchy attractions

Attempts to use colloid science concepts to better understand the dynamic properties of concentrated or crowded protein solutions are challenging due to the fact that globular proteins generally have heterogeneous surfaces that result in anisotropic or patchy contributions to their interaction potential. This is particularly difficult when targeting non-equilibrium transitions such as glass and ge

165 Warncke et Al. Puberty JEndocrSoc 2024

The Influence of Pubertal Development on Autoantibody Appearance and Progression to Type 1 Diabetes in the TEDDY Study The Influence of Pubertal Development on Autoantibody Appearance and Progression to Type 1 Diabetes in the TEDDY Study Katharina Warncke,1,2 Roy Tamura,3 Desmond A. Schatz,4 Riitta Veijola,5 Andrea K. Steck,6 Beena Akolkar,7 William Hagopian,8 Jeffrey P. Krischer,3 Åke Lernmark,9

https://www.teddy.lu.se/sites/teddy.lu.se/files/2024-12/165%20Warncke_et%20al.%20Puberty%20JEndocrSoc_2024.pdf - 2026-05-28

New Hope in Prostate Cancer Precision Medicine? miRNA Replacement and Epigenetics

SPINK1+/ETS- prostate cancer is an aggressive disease with poor clinical outcome. New data suggest a novel treatment by upregulating the expression of miR-338-5p/-421 through epigenetic modulation or by miRNA replacement. This is a new and interesting concept that warrants further exploration in clinical trials.See related article by Bhatia et al., p. 2755.

Longitudinal Speech Outcomes in Foreign-Born and Native-Born Children in Sweden with Cleft Palate, and Influence of Palatal Surgery Timing

Objective To compare longitudinal speech outcomes at ages 5 and 10 years in foreign-born and Swedish-born children with cleft palate with or without cleft lip (CP ± L), and assess impact of cleft type, additional diagnosed conditions, sex, and age at completed primary palatal surgery.DesignLongitudinal, registry-based cohort study.SettingRegional public care university hospitals in Sweden.Particip

Laboratory instructions as a cause of student dissonance

Improving the quality of education is the goal of all pedagogical research. By using student surveys and course evaluations problem areas can be identified in most courses offered by universities. In this paper we perform a large-scale student survey in order to find the causes of, and remedies to, a widespread student dissonance in a mandatory course with over 100 students at Lund University. Our

Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism.

The underlying mechanisms responsible for the development of castration-resistant prostate cancer (CRPC) in patients who have undergone androgen deprivation therapy are not fully understood. This is the first study to address whether β2-adrenergic receptor (ADRB2)- mediated signaling may affect CRPC progression in vivo. By immunohistochemical analyses, we observed that low levels of ADRB2 is assoc