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Findings on the association between alcohol consumption and bladder cancer are inconsistent. We investigated that association in the European Prospective Investigation into Cancer and Nutrition cohort. We included 476,160 individuals mostly aged 35–70 years, enrolled in ten countries and followed for 13.9 years on average. Hazard ratios (HR) for developing urothelial cell carcinoma (UCC; 1,802 inc

The tight junction protein claudin-4 has been reported to be overexpressed in advanced ovarian cancer. We investigated the prognostic significance of claudin-4 overexpression and whether claudin-4 expression could predict platinum response in primary ovarian carcinoma (OC). Claudin-4 expression was evaluated by immunohistochemistry in a tissue microarray of 140 OCs. Multivariable Cox-regression mo

Higher levels of circulating adiponectin have been related to lower risk of colorectal cancer in several prospective cohort studies, but it remains unclear whether this association may be causal. We aimed to improve causal inference in a Mendelian Randomization meta-analysis using nested case–control studies of the European Prospective Investigation into Cancer and Nutrition (EPIC, 623 cases, 623

Background: Recent studies indicate that one of four childhood cancers can be attributed to hereditary genetic abnormalities. Methods: The Lund Childhood Cancer Genetic study includes newly diagnosed childhood cancer patients as well as childhood cancer survivors visiting the Department of Pediatrics or the Late Effect Clinic at Skåne University Hospital, Lund, Sweden. Questionnaires regarding fam

Microhabitat conditions determine the magnitude and speed of microbial processes but have been challenging to investigate. In this study we used microfluidic devices to determine the effect of the spatial distortion of a pore space on fungal and bacterial growth, interactions, and substrate degradation. The devices contained channels differing in bending angles and order. Sharper angles reduced fu

Alzheimer’s disease affects millions of lives worldwide. This terminal disease is characterized by the formation of amyloid aggregates, so-called amyloid oligomers. These oligomers are composed of β-sheet structures, which are believed to be neurotoxic. However, the actual secondary structure that contributes most to neurotoxicity remains unknown. This lack of knowledge is due to the challenging n

Serious outcomes as stroke, arrythmia and death are relatively frequent in patients presenting with dizziness. Within 30 days almost one in five patients re-attended the ED due to dizziness and 2,8% needed ED evaluation due to a fall. Decision support tools to help identify serious conditions and predict preventable falls in ED patients with dizziness are needed.

The complex dynamics of protein expression in plasma during hyperacute HIV-1 infection and its relation to acute retroviral syndrome, viral control, and disease progression are largely unknown. Here, we quantify 1293 blood plasma proteins from 157 longitudinally linked plasma samples collected before, during, and after hyperacute HIV-1 infection of 54 participants from four sub-Saharan African cou

Recent insect decline prompts rapid online monitoring solutions with specificity for thousands of coexisting species.I demonstrate how microscopic and nanoscopic features of insects can aid differentiation of species and be retrieved with spectral lidar.

Rostrocaudal patterning of the neural tube is a defining event in vertebrate brain development. This process is driven by morphogen gradients which specify the fate of neural progenitor cells, leading to the partitioning of the tube. Although this is extensively studied experimentally, an integrated view of the genetic circuitry is lacking. Here, we present a minimal gene regulatory model for rost

The emerging notion of hematopoietic stem and progenitor cells (HSPCs) as a low-primed cloud without sharply demarcated gene expression programs raises the question on how cellular-fate options emerge and at which stem-like stage lineage priming is initiated. Here, we investigate single-cell chromatin accessibility of Lineage-, cKit+, and Sca1+ (LSK) HSPCs spanning the early differentiation landsc

This paper is a report of recommendations for addressing translational challenges in amyloid disease research. They were developed during and following an international online workshop organized by the LINXS Institute of Advanced Neutron and X-Ray Science in March 2021. Key suggestions include improving cross-cultural communication between basic science and clinical research, increasing the influe

Background: Enzalutamide (ENZ), an androgen receptor antagonist therapy, was approved for patients (pts) with mCRPC. However, in standard of care for mCRPC pts, change in prostate specific antigen (PSA) is not accepted as an efficacy response measurement and the radiological change is inadequately measured in an interpreter-dependent subjective analysis of bone scan. Therefore, an objective effica

Now extinct, the aurochs (Bos primigenius) was a keystone species in prehistoric Eurasian and North African ecosystems, and the progenitor of cattle (Bos taurus), domesticates that have provided people with food and labour for millennia1. Here we analysed 38 ancient genomes and found 4 distinct population ancestries in the aurochs—European, Southwest Asian, North Asian and South Asian—each of whic

Brottsoffret har sedan det introducerades som ett begrepp på 1970-talet allt mer kommit att dominera den politiska och akademiska debatten kring brott och straff. Mitt syfte med den här uppsatsen är att ur ett kritiskt perspektiv granska den svenska straffrätten ur ett brottsofferperspektiv. Vem är brottsoffret? Det finns ingen övergripande definition av vem brottsoffret är. En fråga som därför uThe term “crime victim” was introduced in the Swedish language in the 1970s. Since then it has more and more started to dominate the political and academic debate about crime and punishment. My aim with this essay is to from a critical point of view, review the Swedish criminal law from a crime victim-perspective. Who is the crime victim? There is no overall definition of who can qualify as a cri

PNR inbegriper arbetsterapeut-, audionom-, fysioterapeut- och logopedprogrammen. Sammanträdestider Vårterminen 2026Beredningsmöte: 5 majNämndsammanträde: 19 majHöstterminen 2026Beredningsmöte: 15 septemberNämndsammansträde: 29 septemberBeredningsmöte: 20 oktoberNämndsammanträde: 3 novemberBeredningsmöte: 24 novemberNämndsammanträde: 8 december Sammanträden hålls vanligen tre gånger per termin, på

https://www.intramed.lu.se/organisation-och-styrning/namnder-och-kommitteer/utbildning/programnamnder/programnamnden-rehabiliteringsutbildningar-pnr - 2026-05-29

UAS-pilot inom kategorin SPECIFIK, 150 YH-poäng, 40 veckor Utbildningen UAS-pilot inom kategorin SPECIFIK leds av Folkuniversitetet. Lunds universitet Trafikflyghögskolan ansvarar för ett antal av delkurserna och erbjuder en unik utbildnings- och forskningsmiljö vid Campus Ljungbyhed, vilket ger studenter en gedigen kunskapsbas.Utbildningsprogrammet syftar till att utbilda piloter för avancerade f

https://www.flyg.lth.se/tfhs/uas-pilot-specifik - 2026-05-29