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Fast method to find sterically possible amino acid substitutions

Analysing structural damage caused by changes in proteins In an organism, even only one single change of an amino acid can sometimes lead to disease, if the protein is a part of an important biological function. Because of that, it is important to study those changes and be able to predict if an amino acid substitution would cause harm. There are various ways a substitution can be harmful to a pr

A data management framework for strategic urban planning using blue-green infrastructure

Spatial planning of Blue-Green Infrastructure (BGI) should ideally be based on well-evaluated and context specific solutions. One important obstacle to reach this goal relates to adequate provisioning of data to ensure good governance of BGI, i.e., appropriate planning, design, construction, and maintenance. This study explores the gap between data availability and implementation of BGI in urban p

The dangerous path to school and empowerment: a case study investigating the difficulties of empowerment in education for girls in West Kalungu County District, Uganda

Getting girls to go to and ​stay​ in school is a worldwide issue - predominantly in the global south where it is a particular problem in Sub-saharan Africa where poverty is particularly high. This issue is also one of gender, as the majority of children who do not have access/go to school are female. This paper investigates this problem in central western Uganda, in the west county of the Kalungu