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The inflammatory mediator leukotriene B(4) (LTB(4)) binds to and activates a G-protein-coupled receptor named BLT(1). We have previously produced two monoclonal antibodies, named 7B1 and 14F11, that bind specifically to this receptor. Using a HeLa cell line expressing human BLT(1), we find that both antibodies inhibit LTB(4)-induced calcium release, and activation of a MAP-kinase-sensitive lucifer
This study was aimed at investigating the psychometric properties of the Interview Schedule for Social Interaction (ISSI), in terms of construct and discriminant validity and unidimensionality, in three psychiatric samples with varying prerequisites for social interaction: 1) an outpatient sample of working age with mixed diagnoses, 2) an outpatient sample with schizophrenia, and 3) an inpatient s
Electrical characteristics of living tissues have been investigated for a long time in the search for further methods to complement the traditional investigations of pathology and physiology. Tumour tissue has been shown to exhibit a larger permittivity and conductivity than normal tissues. This might be associated with the fact that tumour cells have a higher water content and sodium concentratio
Fluorescence in situ hybridisation (FISH) is a common and popular method used to investigate microbial populations in natural and engineered environments. DNA oligonucleoticle probes require accurate determination of the optimal experimental conditions for their use in FISH Oligonucleotides targeting the rRNA of methanogenic Archaea at various taxonomic levels have previously been published, altho
The gallium abundance in HgMn stars has been reported to be different for analyses conducted from spectral lines in the optical versus those from the ultraviolet. We pursue this ultraviolet-optical discrepancy from a line-blending perspective by investigating the Hubble Space Telescope (HST) Space Telescope Imaging Spectrograph (STIS) spectrum of the sharp-lined HgMn binary star chi Lup. Its galli
Host-related and environmental factors for tuberculosis have usually been investigated separately using different study designs. Joint investigation of the genetic, immunologic, and environmental factors at play in susceptibility to tuberculosis represents an innovative goal for obtaining a better understanding of the pathogenesis of the disease. In this paper, the authors describe methods being u
Wireless sensor networks are composed of a large number of sensor nodes with limited energy resources. Once deployed, the sensor nodes are usually inaccessible to the user, and thus replacement of the energy resource is not feasible. Hence, energy efficiency is a key design issue that needs to be enhanced in order to improve the life span of the entire network. Several routing protocols have been
Arsenic enrichment of groundwater in the Red River (Song Hong) delta in Vietnam was discovered in 1998. Several studies performed in this area found concentrations of As exceeding the WHO-guideline of 10 lg/L. This study focuses on an area south of Hanoi city, Nam Du, where a new well field came into operation in 2004. The new well field is situated on the bank along the Red River in order to faci
Molecular factors control the developmental ingrowth of axons to the tooth pulp. Here we examine the ability of pulpal cells to induce neurite outgrowth from neonatal rat trigeminal neurones (TGNs) in vitro. We found that TGNs emitted neurites and formed networks of branches in relation to pulpal cells. Neurones co-cultured with a mixture of pulpal cells and 3T3 fibroblasts formed networks exclusi
Conversion of lignocellulosic material to monomeric sugars and finally ethanol must be performed at low cost, i.e, with limited consumption of chemicals, yeast and enzymes while still reaching high yields, if it is to compete with other fuel conversion processes. The objective of this study was thus to investigate ethanol production from steam-pretreated wheat straw by simultaneous saccharificatio
A virtual reality (VR) experiment with 96 participants was carried out in a Cave Automatic Virtual Environment (CAVE) laboratory at Lund University to provide recommendations on the design of flashing lights at emergency exit portals for road tunnel emergency evacuation. A set of variables were investigated, namely 1) Colour of flashing lights, 2) Flashing rate, 3) The type of light source, 4) The
In this thesis computationally intensive methods are used to estimate models and to make inference for large, spatio-temporal data sets. The thesis is divided into two parts: the first two papers are concerned with video analysis, while the last three papers model and investigate environmental data from the Sahel area in northern Africa. In the first part of the thesis, mixture models are used to
Glass sheets investigated regarding their Po-210 signal originating from indoor radon exposure will have a depth distribution down to about 100 nm. The geometrical probability of implantation into glass of glass-attached radon daughter activity in one alpha recoil event is 50%. A particulate layer on the glass sheet (dust, grease or other particles) will stop the alpha recoil nucleus partly or tot
The aim of this book is to explore how contemporary notions of reconciliation as a process of building, rebuilding and transforming relationships may be applied not only to “race” but also to gender relations in post-apartheid and post-TRC South Africa. After highlighting links between the past, the present and the future with regard to such relations in wider South African society, critical quest
