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The molecular basis of human igg-mediated enhancement of C4b-binding protein recruitment to group a streptococcus
Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.
The Internalization of External Effects in Swedish Transport Policy - A Comparison Between Road and Rail Traffic
Popular Abstract in Swedish De nu gällande trafikpolitiska principerna för kostnadsansvaret lades fast i 1988 års trafikpolitiska beslut (Regeringens proposition 1987/88:50 om trafikpolitiken inför 1990-talet). Utgångspunkten för kostnadsansvaret är trafikavgifter på samhällsekonomiska villkor med syfte att ge rätt beteendesignaler på transportområdet. Från denna utgångspunkt har kostnadsansvaret