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Metalloenzymes are proteins that contain one or more metal ions bound to protein. They constitute about one-third of all enzymes known so far and they often perform hard chemical reactions involving small substrates, like H2 and N2. In our research, we focus on those metal ions that are located in the active sites and perform redox reactions, i.e. involving electron transfer. Why enzymes?Metalloenzymes catalyse a wide variety of reactions in nature. In the thesis, I have studied the reaction mechanism of three metalloenzymes, viz. [NiFe] hydrogenase (H2ase), dimethyl sulfoxide reductase (DMSOR) and formate dehydrogenase (FDH), by theoretical methods, namely quantum mechanics (QM), combined quantum mechanical and molecular mechanics (QM/MM), as well as QM/MM thermodynamic cycle per
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Title: Perceiving the Mundane Necessity - How Consumers Perceive Pharmacies in an Increasingly Competitive Swedish Market Course: BUSN39 - Degree Project in Global Marketing Authors: David Ingvarsson & Oscar Egard Supervisor: Tommy Shih Purpose: The purpose of our study is to identify and gain an understanding of how consumers perceive pharmacies on the Swedish pharmaceutical market. More spec
Inresande forskningspraktikanter
20191022 Inresande forskningspraktikanter (grund- eller masterstudenter) Den internationella kommittén vid Institutionen för psykologi har beslutat om riktlinjer för att skapa bra förutsättningar för ett ömsesidigt givande forskningssamarbete mellan inkommande forskningspraktikanter samt ansvariga forskare. Då du som forskare blir kontaktad av internationella studenter som önskar delta i ett forsk
https://www.psy.lu.se/sites/psy.lu.se/files/inresande_forskningspraktikanter.pdf - 2026-07-12
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Background: The demographic shift is fast becoming a global challenge. Populations ageing rapidly is widely seen as one of the most powerful transformative forces affecting society over the next four decades.Due to the demographic challenge in most countries it is important to consider making working life sustainable. It is obvious that the main factor that distinguishes senior workers from other
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Towards a theoretical model with an impact on a sustainable working life for all ages, the swAge – model (https://swage.org/en.html)
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In this project, nanoimprint lithography has been applied to define gold particles on the surface of an InP wafer. For achieving this aim, a dry etching process has been developed to create resist undercut for the lift-off. In order to prepare the required undercuts, RIE parameters were optimized and desired undercuts were made at etch times of 80 s to 120 s. Also, to obtain anisotropy and high et
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De vanligaste kontakterna under vikingatiden ur ett svenskt perspektiv gick österut. Miljontals islamiska mynt flödade in i Skandinavien från Nordafrika, kalifatet och det samanidiska herraväldet i Centralasien. Deras ursprung varierade, och silverströmmens kronologi gör det möjligt att beskriva föränderliga relationer mellan aktörerna. Några välkända artefakter från samma riktning kom till Skandi
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Many contemporary work organizations are concerned with how they can influence employees’ intrinsic motivation. Their quest follows a widespread realization that people do not necessarily work harder because of monetary incentives or direct commands. Instead, people’s inner motives, their urge to self-realize and get recognition, are seen as key factors influencing workers’ mindsets and behaviors.
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Fluxes of methane, CH4, were measured with the eddy covariance (EC) method at a small boreal lake in Sweden. The mean CH4 flux during the growing season of 2013 was 20.1 nmol m−2 s−1 and the median flux was 16 nmol m−2 s−1 (corresponding to 1.7 mmol m−2 d−1 and 1.4 mmol m−2 d−1). Monthly mean values of CH4 flux measured with the EC method were compared with fluxes measured with floating chambers (
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The free energy of interaction between two nanometric clay platelets immersed in an electrolyte solution has been calculated using Monte Carlo simulations as well as direct integration of the configurational integral. Each platelet has been modeled as a collection of charged spheres carrying a unit charge-the face of a platelet contains negative charges, and the edge, positive charges. The calcula
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Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e. unfolded protein response (UPR), play key roles in proteostasis but their involvement in t
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For the past fifteen years, ever since the Court of Justice’s ruling in its landmark case Bosman, the sporting rules governing player mobility have been a hot topic. The ruling prohibited transfer fees for players out-of-contract thus putting an end to the restrictive transfer system hindering the free movement of football players. The Court also abolished the nationality restriction where clubs w
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At the present conjuncture of political, economic, social, and ecological crises, it is important to pay attention to the ways in which intensifying demands for equality, sustainability and social inclusion are met in education policy. In this article, we present results from a critical discourse analysis of an EU council recommendation on ‘microcredentials’ – credits for short courses primarily o
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Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We
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Background: Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients' preferences for attribute
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Purpose: The purpose of this thesis is to critically explore how a regulatory, community and organizational stakeholder perceive their role in the context of sustainability reporting as well as identify convergence and divergence between these different stakeholder perceptions. Methodology: We chose a qualitative-abductive approach to our case study of sustainability reporting by interviewing th
