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Denna uppsats fokuserar på offentliga upphandlingar och behandlar begreppet onormalt låga anbud. Dessa anbudens låga nivå kan vara grundade i dolda motiv eller missförstånd från anbudsgivaren. Detta medför att den upphandlande myndigheten kan vilja förkasta det aktuella anbudet. Den låga nivån kan däremot lika gärna vara helt legitimt och bör därmed inte förkastas. Regelverket samt praxis på områdThis thesis focuses on public procurements and deals with the concept of abnormally low tenders. The low levels in a tender can be founded in a hidden agenda or in a misunderstanding by the tenderer. This means that the contracting authority may wish to reject the current offer. The low level, on the other hand, can just as easily be completely legitimate and should therefore not be discouraged. T

Marknaden för kontor är till stor del beroende av läget av fastigheterna. Det finns stora skillnader i hyresnivåer mellan olika lägen och vad som gör att företag har en högre betalningsvilja för vissa lägen beror på flera lägesfaktorer. Syftet med studien är att identifiera lägesfaktorer som har betydande påverkan på hyresnivåer. Vidare är syftet att kvantifiera och analysera värdepåverkan. Genom The market for offices in urban environments is largely dependent on the location of the properties. There are differences in the level of office rents depending on location, characteristics and attributes in the location. The purpose of the study is to identify the location attributes that have a significant impact on rental levels. Furthermore, the aim is to quantify and analyse the impact value

When deciding upon the usage of direct deliveries as opposed to central inventories, efficiency and strategic effects need to be considered. Operations management literature on efficiency effects is not hard to find but literature describing what other factors can affect the decision is more scarce. Even less literature can be found on the theme of deciding between direct or indirect physical flow

Exploring the potential of biotechnological Tools Protein production has always been a vital part in many studies, which has enabled us to produce proteins that are e.g. used for medicinal purposes, such as insulin. In order to achieve this, one must first obtain an adequate amount of protein. The production of proteins is achieved by utilizing bacteria, which can produce foreign proteins from in

We have conducted a detailed investigation of the broadband spectral properties of the gamma-ray selected blazars of the Fermi LAT Bright AGN Sample (LBAS). By combining our accurately estimated Fermi gamma-ray spectra with Swift, radio, infra-red, optical, and other hard X-ray/gamma-ray data, collected within 3 months of the LBAS data taking period, we were able to assemble high-quality and quasi

Systemic Lupus Erythematosus (SLE) is characterized by chronic inflammation involving many organ systems. The etiology is unknown and the pathogenesis has not been fully elucidated. Impairments of the immune system and of the mechanisms regulating cell death are commonly seen in SLE patients. Autoantibodies, in particular anti-dsDNA antibodies, are considered hallmarks of SLE, but the ideal biomar

The political objectives on national and international levels towards a larger proportion of renewable energy require considerable planning activities on a local level. These activities inevitably must relate to the local community and its various groups; their culture, economy, social activities as well as their views on environmental problems and nature values. This applies to all energy plants.

Detta är en utvärdering av en metod som syftar till att utveckla och effektivisera samverkan mellan myndigheter i en kommun; Gemensamma Individuella Handlingsplaner, GIH. En grupp handläggare från fyra myndigheter har arbetat fram metoden inom ett delprojekt ingående i ett större lokalt samverkansprojekt, FRISAM. Projektet riktar sig till personer med många myndighetskontakter, försörjningsstöd oc

Background: Vel blood group expression is dependent on Small Integral Membrane Protein 1 (SMIM1), a recently discovered erythroid protein. SMIM1 consists of 78 amino acids (aa) and shows only limited homology to other human proteins but is evolutionarily conserved, indicating its importance. The protein has a predicted transmembrane domain but the direction of insertion into the red blood cell (RB

Även om vi skulle lyckas minska de globala utsläppen av växthusgaser, så finns det ett angeläget behov att anpassa samhället för att kunna motstå klimatförändringens skadliga effekter. Denna process kallas klimatanpassning. Städer står inför särskilda risker från klimatförändringen och nuvarande tillvägagångssätt, som ofta förlitar sig på tekniska lösningar och toppstyrd implementering, bedöms intEven if current attempts to reduce global greenhouse gas emissions would succeed, society-wide adjustment to the harmful effects of climate change is urgently needed. This process is known as climate adaptation. Cities face particular risks from climate change, and there is increasing evidence that traditional approaches, which have often relied on technical solutions and top-down management struc

The morphological transformation of soot particles via condensation of low-volatility materials constitutes a dominant atmospheric process with serious implications for the optical and hygroscopic properties, as well as atmospheric lifetime of the soot. We consider the morphological transformation of soot aggregates under the influence of condensation of vapors of sulfuric acid, and/or limonene oz

Innovation plays an important role in organization survival and longevity. This is especially true in the retail industry; there is a growing acknowledgment of the role of innovation in retail practice, as maintaining the status quo might prove insufficient, especially for traditional retailers, in addressing the enormous challenges they are facing driven by technological developments and evolving

Ongoing consumption of fossil-based fuels generates a massive amount of greenhouse gases. This may lead to global warming that is currently threatening human society and wild animal habitats. Hydrogen is an energy carrier with the highest energy content per weight compared to other all fuels and no carbon dioxide is released when combusted. Thermophilic bacteria belonging to the genus of Caldicell

BACKGROUND AND OBJECTIVES: Phosphorylated tau (P-tau) in cerebrospinal fluid (CSF) is considered an important biomarker in Alzheimer's disease (AD) and has been incorporated in recent diagnostic criteria. Several variants exist, including P-tau at threonines 181 (P-tau181), 217 (P-tau217) and 231 (P-tau231). However, no studies have compared their diagnostic performance or association to amyloid-β

Today, between 8% and 16% of all individuals worldwide suffer from chronic kidney disease (CKD), which is becoming a growing public health issue. Creatinine and cystatin C are commonly used markers for kidney function, and estimated glomerular filtration rate (eGFR) and albuminuria are used to stage CKD. However, creatinine and eGFR are rather insensitive in identifying individuals at high risk of

East African landscapes today are the result of the cumulative effects of climate and land-use change over millennial timescales. In this review, we compile archaeological and palaeoenvironmental data from East Africa to document land-cover change, and environmental, subsistence and land-use transitions, over the past 6000 years. Throughout East Africa there have been a series of relatively rapid

Benzodiazepine receptor binding heterogeneity evident from differential affinities of some ligands was compared with that suggested by differential interactions with γ-aminobutyric acid (GABA)/bicuculline and pyrazolopyridine/barbiturate receptor sites. The GABA receptor antagonist bicuculline only partially reverses pentobarbital enhancement of [3H] diazepam binding in rat brain membranes, while

The breakup of the L-chondrite parent body (LCPB) in the asteroid belt at 466 Ma ago is the largest asteroid breakup documented in Earth's geological record for the past ca. three billion years. Recovery of abundant macroscopic fossil L chondrites in mid-Ordovician marine sediments as well as reconstructions of the flux of micrometeoritic chrome spinel through the ages have given much new informat

Proton therapy has the potential to improve the local control rates and reduce the risk of toxicity forlung cancer patients. However, the delivery of proton therapy is prone to uncertainties caused byanatomical changes and motion during the treatment and between the treatment fractions whichmay compromise its effectiveness. The dosimetric uncertainty of lung cancer proton therapy can beminimized t

Syftet med studien är att synliggöra ett konfliktfält med berättelser om det moderna Sverige som uttrycks av olika politiska grupper och att främja bearbetningen av tolkningskonflikten. Fyra politiska utmaningar mot den etablerade framgångsberättelsen om Sveriges utveckling från ett fattigt land till en modern välfärdsstat analyseras: 60-talsvänstern, den nya kvinnorörelsen på 1970-talet, alternatThe aim of the study is to make visible a field of conflicting narratives of modern Sweden expressed by different political groups and to contribute to the working through of the conflict of interpretation. Four political challenges to the established success story of Sweden's development from a poor society to modern welfare state, are analysed: the Left in the 1960s, the new Women's movement in