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Dynamics of GABA Receptor composition in the recovery phase of stroke – Effect of anti-inflammatory treatment with AMD3100

GABAergic Neurotrasmission – A “cross-talker” between inflammation and neural plasticity in stroke Stroke is a leading cause of disability and no pharmacological treatment is currently available to promote recovery in suffering patients. A major part of research is focusing on finding new biological targets which can be pharmacologically intervened with, providing favorable results in facilitatin

Influence of constructed wetlands on cyanobacterial growth with regards to the effect of nutrient concentrations and water colour

Can constructed wetlands be used to fight cyanobacterial blooms? Cyanobacterial blooms are more than just a nuisance that prevents swimmers from making the most of the warmest months. Cyanobacterial blooms can cause a wide array of problems such as polluting freshwater reservoirs and causing fish die offs, owing to their ability to grow rapidly and release toxins which are harmful to both humans

Tvångsvård av unga som använder sex för att skada sig själva - En kritisk diskursanalys om hur sex och det sexuellt självskadande rättssubjektet framställs vid tillämpningen av 3 § LVU på förvaltningsrättsnivå

Genom samhällsutvecklingen utmanas gamla sjukdomsbegrepp och lagar. I medierapportering och forskning har självskadebeteende uppmärksammats allt mer. Självskadebeteenden kan ta olika uttryck och även sex har påvisats kunna utgöra ett medel för att skada sig själv. Idag finns det medicinsk forskning om sex som självskadebeteende och rättsvetenskaplig forskning om tillämpningen respektive tolkningenSocietal development is constantly challenging old concepts of disease and law. In media reporting and medical research, self-injurious behavior has received increased interest. Self-injurious behavior can be expressed in various forms. Sex as self-injury is a new concept in the research field and the current knowledge of sex as self-injury did not exist when the Care of Young Persons Act, hereaft

Utländsk arbetskrafts påverkan på byggbranschen

I studien undersöks utmaningar och förbättringsförslag relaterade till arbetsmiljö, säkerhet och kommunikation inom byggindustrin för utländska arbetstagare, med extra fokus på länderna Polen och Litauen. Fri rörlighet för arbetstagare inom EU, som fastställs av artikel 45 i EUF-fördraget, möjliggör lika tillgång till både arbetsmöjligheter och behandling oavsett nationalitet. Syftet med studien The study examines challenges and improvement suggestions related to the work environment, safety, and communication within the construction industry for foreign workers, with a particular focus on Poland and Lithuania. The free movement of workers within the EU, as established by Article 45 of the treaty on the functioning of the European Union, ensures equal access to both employment opportuniti

Risker med DNA-bevisning - En kvalitativ undersökning av svenska domstolars hantering av berörings-DNA och riskerna med sekundäröverföring

Uppsatsen undersöker bevisrättsliga och processuella risker förenat med be-visning som består av berörings-DNA och invändningar från den tilltalade att DNA-spåret tillkommit genom sekundäröverföring. De risker som identifierats är att berörings-DNA är behäftat med vissa osäkerheter. Forskning har visat att sådana spår i vissa fall kan överföras genom ett eller flera mellanled. Samtidigt har HD i sThis thesis examines evidentiary and procedural risks associated with evi-dence consisting of touch DNA and objections from the defendant that the DNA trace was transmitted through secondary touch-transfer. The risks identi-fied are that touch DNA is subject to certain ambiguities. Research has shown that such traces can be transmitted through one or more intermediate links. Concurrently, the Swed

Young today-adult tomorrow! Studies on physical status, physical activity, attitudes, and self-perception in children and adolescents

The aim was to gain knowledge of young people's physical status and physical activity, and to further the understanding of the role of school physical education in a salutogenic public health perspective. Two studies were performed in southern Sweden. Study 1 was performed in 1996 among 301 adolescents aged 16-19 in upper secondary school. It comprised three parts: a questionnaire, seven physical

Actions of Antimicrobial Peptides and Bacterial Components in Inflammation

Antimicrobial peptides are evolutionally ancient parts of the innate immune system and their primary role is to protect us from infections. The human cathelicidin-derived antimicrobial peptide, LL-37, not only possesses broad spectrum antimicrobial activities but is also able to bind and neutralize bacterial lipopolysaccharide (LPS), an important trigger of the widespread inflammatory response con

Genetic and Environmental Risk Factors in the Development of Obesity

Lifestyle behaviors and genetic variation have clear and distinguishable effects on obesity risk; however, the pattern of disease occurrence within and between populations that differ in their genetic and environmental underpinnings suggests obesity is caused in part by the interaction between adverse lifestyle behaviors and the genetic risk profile of an individual. This thesis aims to investigat

Model-Based Control of Gasoline Partially Premixed Combustion

Partially Premixed Combustion (PPC) is an internal combustion engine concept that aims to yield low NOx and soot emission levels together with high engine efficiency. PPC belongs to the class of low temperature combustion concepts where the ignition delay is prolonged in order to promote the air-fuel-mixture homogeneity in the combustion chamber at the start of combustion. A more homogeneous combu

Developing General Practice: The Role of the APO method

Abstract General practice is a broad and multifaceted field of knowledge. Political steering instruments declare that general practice and primary care are characterized by a holistic perspective on the individual, with quality, accessibility, continuity, and cooperation being important factors. For the last few decades, quality assurance has been in focus in Swedish health care. Inspiration has c

Daily occupations among asylum seekers- Experience, performance and perception

Asylum seekers often find themselves in a situation where the structure and content of daily occupations have been disrupted and they might have limited access to paid work and education. Studies have shown that asylum seekers experience occupational depri- vation and a change in daily occupations which might even influence their identity. Such deprivation can eventually lead to dissatisfaction wi

Involvement of non-dopaminergic systems in L-DOPA-induced dyskinsia

Popular Abstract in Swedish Parkinsons sjukdom är en av våra vanligaste ålderssjukdomar i Sverige och drabbar en procent av befolkningen över 50 år. De karaktäristiska symptomen: skakningar, långsamma rörelser och stelhet orsakas i huvudsak av en förlust av nervceller som producerar signalsubstansen dopamin i hjärnan. Den mest effektiva behandlingen är L-DOPA, som i hjärnan omvandlas till dopamin.Parkinson's disease and L-DOPA-induced dyskinesia (LID) does not merely involve the dopamine (DA) system but also include non-dopaminergic systems such as glutamate and serotonin (5-HT). An aberrant glutamate transmission at the corticostriatal synapse, has been linked to LID. Pharmacological agents to glutamate receptors at this synapse, (of which some are already clinically tested), could preve

The potential impact of changing vegetation on thawing permafrost : effects of manipulated vegetation on summer ground temperatures and soil moisture in Abisko, Sweden

Populärvetenskaplig sammanfattning Arktis har under de senaste årtiondena upplevt betydande uppvärmning och enligt prognoser förväntas ytterligare höjningar av både lufttemperatur och nederbörd under det kommande århundradet. Det förändrade klimatet har haft omfattande konsekvenser för permafrosten (ständigt frusen mark) som format och kraftigt präglar stora delar av det arktiska landskapet. Med öThe Arctic region has experienced significant warming in the past decades and according to predictions further increases in air temperatures and precipitation will occur during the 21st century. Recent changes in climate have had widespread implications for the permafrost around the Arctic. Shorter periods of snow covering the Arctic regions significantly reduce the average annual albedo which dra

Investigating the effect of phosphorylation on DivIVA oligomerization in Streptomyces coelicolor

Streptomyces belong to the phylum Actinobacteria, which are Gram-positive bacteria with GC-rich DNA. Most Streptomyces are strict aerobes and inhabit soil. They are known for production of a wide range of secondary metabolites, including antibiotics e.g. the macrolide erythromycin (S. erythraeus) or chloramphenicol (S. venezuelae). The typical smell of wet soil is owed to geosmin, also a secondary

Förändrad gradindelning och straffvärdebedömning för narkotikabrott - revolution eller tillnyktring?

Narkotika har sedan 1960-talet utgjort ett allvarligt samhällsproblem i Sverige. En skyndsam utbredning har varit en bidragande faktor till stor del av den grova brottsligheten i landet. På 1970-talet infördes målet om ett narkotikafritt samhälle i Norden, vilket sedan dess varit ledande för Sverige. Utmärkande för Sveriges narkotikapolitik är ett strängt och restriktivt förhållningssätt. Ett narkDrugs were noted as a serious public issue in Sweden during the 1960s with its accelerated expansion and conduciveness to heavy criminality. During the 1970s, the drug policy towards a drug free society was introduced in the Nordic region, and is still today advocated in Sweden. The drug policy in Sweden is known for the severe and restrictive approach. The drug policy has characterized the Swedis

Understanding Customer Needs in Canada – Importance of Marketing Research Excellence in a Market Oriented Organization

Company X Equipment division is a mature organization that has experienced a desire to broaden the knowledge about the market potentials of the Canadian markets. There is also an ambition within the organization to improve the sales in Canada by exploring previously unknown market opportunities. The needs for increased knowledge are experienced both at the Canadian sales office and at the Lund hea

Sensor Array Optimization for Multiple Harmonic Sound Source Separation and DOA

INTRODUCTION In the last years a lot of researches about source separation have been realized, like extraction of a signal of interest (vocal recognition application), identification of which source gives which sound (motor engine applications) or noise source characterization (environmental application). Most of these techniques for sound source estimation use the signal-subspace approach, where

Downloading and filesharing through Peer-to-peer networks: the copyright versus the free access to the cultural products

The “peer to peer” (P2P) is a technology of downloading and filesharing between online - Internet - users by the mean of specified software. Since June 1999, the Napster software has made the happiness of millions of individuals who used it to obtain and share free audio files Mp3. Rapidly, the major recording companies have prosecuted the Napster Company and managed to force it to close down. The

Performance Management A Case Study in YingChao Co. Ltd, Beijing China

In 21 century, with the trend of globalization, both large and small organizations are facing an environment characterized by extremely high level of competition. In order to be competitive, China's managers are endeavouring to try every effort to improve employees' performance within sound organizational culture, thus to improve organizations' competence. Yet as a matter of fact, sinc