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The plutonic rocks in the Western Segment of the Southwestern Swedish Gneiss Complex show a distinct geochemical evolution. The 1.6 Ga Åmål granitoids and Slottsbron migmatites are a quartz dioritic to granodioritic, calc-alkaline rock suite with smooth, but somewhat fractionated, REE and other trace-element patterns. The younger microcline granites of the 1.5 Ga and 1.3 Ga generations are evolved
Popular Abstract in Swedish Extremt stora teleskop, optisk konstruktion och vågfrontskorrektion 1 Nya resultat inom astronomin För astronomin har senare årtionden varit ytterst händelserika. Ett flertal fascinerande upptäckter har förädlat vår kunskap om universum och dess stjärnor, planeter, galaxer och storskaliga strukturer. Vi har fått bättre grepp om universums ålder, struktur och utvecklinAn overview of the state of art within optical design of large astronomical telescopes is given. Recent advances within the field are presented. The importance of new computer-controlled mirror-polishing methods is emphasized. Some important aspects of atmospheric optics are presented together with current compensation methods using adaptive optics, with or without laser guide stars. An overview o
Popular Abstract in Swedish Cancerförekomst i familjen är en riskfaktor för flera vanliga cancerformer. Såväl ärftlig (hereditär) som icke-ärftlig (sporadisk) cancer är resultatet av en ansamling av förändringar (mutationer) i gener vars normala funktion är att reglera cellernas delning, tillväxt och mognad. Vid ärftlig cancer finns den första erforderliga mutationen i kroppenThis thesis focuses on one of the most common types of hereditary cancer, hereditary nonpolyposis colorectal cancer (HNPCC). This syndrome is characterized by an autosomal dominant inheritance, an increased risk for several types of cancer (especially cancer of the colorectum, small bowel, endometrium, ovary and urinary tract), early age at diagnosis, and frequent development of multiple primary m
Layered anorthosite complexes are typical components of Archean crustal domains. However, the geodynamic settings in which they were emplaced are still discussed as geological relationships are often ambiguous. Here we report major, trace element and high-precision high-field-strength-element (HFSE) data for the recently discovered well preserved Naajat Kuuat Anorthosite Complex from the inner Ame
High resolution palaeoenvironmental records in Far-Eastern Russia are rare, and the Kamchatka Peninsula is among the least studied areas of the region. This paper describes a record spanning the last ca. 11,000 yr, obtained from a bog in the southern part of Kamchatka. The radiocarbon dated core was analysed for pollen, testate amoebae, charcoal and loss-on-ignition (LOI). The vegetation during th
Negative pressure wound therapy in cardiac surgery Rainer Petzina, M.D. Clinical Sciences, Lund, Lund University Poststernotomy mediastinitis is a devastating complication for patients undergoing cardiac surgery. Conventional treatment includes surgical revision, continuous irrigation with drainage and wound closure with the use of the greater omentum and muscle flaps. Widespread adoption of ne
Introduction: Basal-like breast cancers (BL-BCa) have the worst prognosis of all subgroups of this disease. Hyaluronan (HA) and the HA receptor CD44 have a long-standing association with cell invasion and metastasis of breast cancer. The purpose of this study was to establish the relation of CD44 to BL-BCa and to characterize how HA/CD44 signaling promotes a protease-dependent invasion of breast c
Background Carriers of APOE epsilon 2 and epsilon 4 have an increased risk of intracerebral haemorrhage (ICH) in lobar regions, presumably because of the effects of these gene variants on risk of cerebral amyloid angiopathy. We aimed to assess whether these variants also associate with severity of ICH, in terms of haematoma volume at presentation and subsequent outcome. Methods We investigated the
Coals with similar thermal maturity and from the same deposit normally show a considerable range in petroleum generation potential as measured by the Hydrogen Index (HI). This variation may partly be related to variations in plant input to the precursor mires and organic matter preservation. It is widely accepted that some Cenozoic coals and coaly sediments have the potential to generate oil, whic
Popular Abstract in Swedish Moderns rökning under graviditet och risk för medfödda missbildningar. Ungefär två procent av alla nyfödda föds med någon missbildning såpass allvarlig att den rapporteras till missbildningsregistret och/eller till det medicinska födelseregistret. Trots alla samhälleliga insatser för att minska rökningen (speciellt i samband med graviditet) så röker (1996) 16% av de grAbout two percent of Swedish newborn infants are born with a significant congenital malformations which is reported to the Swedish Registry of Congenital Malformations (RCM), and/or the Swedish Medical Birth Registry (MBR). In spite of persistent public health recommendations, about 16% of the Swedish pregnant women are smoking during pregnancy (1996). It is well known that maternal smoking during
Popular Abstract in Swedish I djurvärlden finns två dominerande ögontyper: kameraögon och facettögon. Kameraögat har en enda lins som fokuserar en bild på ögats retina, medan facettögon har många delögon som var och en har en lins. Båda typerna av ögon hittas inom Arthropoda men facettögon är klart vanligast. Det mest spridda typen av facettöga kallas appositionsöga och har en lins till varje ljusIn the superposition compound eye each rhabdom (light sensitive unit) receives light through many ommatidial facets, while in the apposition compound eye every rhabdom receives light from a single facet. The superposition design increases photon capture, which is an advantage in dark environments. Despite their advantage in dim light, superposition eyes can sometimes be found in insects that live
During the 1920s, when the Swedish defence was under heavy debate, military and conservative forces on the right tried to turn the Swedish public opinion towards a climate more in favour of the defence by producing a big budget war film – Karl XII. In several senses the film became a great success. In Sweden the attendance figures were as high as one million (of a population of six) and the film w
Background & aims: alpha-Ketoglutarate (AKG) has been suggested to play a particular role as an oxidative fuel for the gut, and thus may have a sparing function for fuels such as glutamate and aspartate. Using the pig model we aimed to quantify how the route of administration (intravenous, i.v.; intragastric, i.g.; intraduodenal, i.d.) affects AKG utilization, whole body energy expenditure (EE
1. The dilator effect of extracellular adenosine triphosphate (ATP) has mainly been characterized as a direct effect on smooth muscle or as an endothelium-dependent effect mediated by nitric oxide (NO) or prostaglandins. We tested the hypothesis that endothelium-derived hyperpolarizing factor (EDHF) may also be involved. Dilator effects were studied in vitro by continuous recording of isomeric ten
Popular Abstract in Swedish Utbredningen av besvär som attribueras till elektrisk utrustning respektive kemikalielukter och andra odörer är ännu ej till fullo fastställd. Vidare saknas kunskap om eventuella bakomliggande faktorer för dessa besvärs uppkomst. Syftet med avhandlingen var att undersöka utbredningen av besvär som attribueras till elektriska faktorer, kemikalier och lukter, samt undersSelf-reported annoyance from electrical equipment has been in evidence since the mid-eighties, and the first reports of illness from everyday chemicals arose already in the 1960?s. However, the extent of the problem or the mechanisms behind the development of environmentally related annoyance has not yet been fully established. Increased vulnerability to stress has been suggested to be a possible
Acute myeloid leukemia (AML) is a fatal disease that is characterized by a rapid expansion of myeloid leukemic blasts with impaired differentiation that accumulate in the bone marrow. The prognosis for AML is generally poor, with a five-year overall survival of around 20% in patients over 60 years old. Current AML treatment strategies, including chemotherapy and hemapoietic stem cell trasplantatio
The ongoing 2023 Israel-Hamas War has severe and far-reaching consequences for the people, economy, food security, and environment. The immediate impacts of damage and destruction to cities and farms are apparent in widespread reporting and first-hand accounts from within the Gaza Strip. However, there is a lack of comprehensive assessment of the war's impacts on key Gazan agricultural land that a
divided the data set temporally, assessing the persistence of identified subgroups over different periods. The reassessment of mortality risk used the targeted maximum likelihood estimation (TMLE) method to achieve more robust causal modeling. Results: We analyzed data from 21,005 children. The mortality risk (6 weeks to 3 years of age) was 5.2% (95% CI 4.8%-5.6%) for children born between 2003 an
In the search for low greenhouse gas propulsion, the dual fuel engine provides a solution to use low carbon fuel at diesel-like high efficiency. Also a lower emission of NOx and particles can be achieved by replacing a substantial part of the diesel fuel by for example natural gas. Limitations can be found in excessively high heat release rate (combustion-knock), and high methane emissions. These
Amputation of a hand is a life-changing event, and the loss of motor and sensory functions leads to disability and has devastating effects on the individual. What is normally performed using two hands must be solved with only one, and the loss also affects body balance and body posture. In addition, amputation of a hand has psychological effects, and has an influence on social life, participation,
