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What accounts for the differences in the economic performance across Italian regions in the post-Unification period? This thesis seeks to explain the regional patterns of economic development and industrialization in Italy in the period 1871-1911 by applying various Economic Geography models. The first part follows Overman and Puga (2002) and studies the distribution of industrial employment acros
The myc family of genes contains five functional members. We describe the cloning of a new member of the myc family from rat genomic and cDNA libraries, designated B-myc. A fragment of cloned B-myc was used to map the corresponding rat locus by Southern blotting of DNA prepared from rat X mouse somatic cell hybrids. B-myc mapped to rat chromosome 3. We have previously mapped the c-myc to rat chrom
Monoclonal antibodies ofatumumab (anti-CD20) and alemtuzumab (anti-CD52) which are approved for usage in patients with chronic lymphocytic leukemia (CLL), efficiently activate the classical complement pathway. However complement is an exhaustible component and high doses of its activators may deplete complement-dependent cytotoxicity (CDC) potential, thus reducing the effect of repeated mAb dosing
Background: Neuroblastoma is the commonest extracranial solid tumor of childhood, yet rare, and with poor survival before 1990, especially for high-risk disease; thus, information on late effects is sparse. With great advances in cancer treatment, survival has reached 80% in the Nordic countries. The aim of the study was to investigate the risk of developing neurologic disorders after neuroblastom
Objectives: Guidelines recommend a single high-sensitivity cardiac troponin T (hs-cTnT) ≤14 ng/L measured ≥6 h after chest pain onset combined with a GRACE score <140 and the patient being pain-free for ruling out myocardial infarction (MI). There is however little data on the performance of this strategy. We therefore aimed to evaluate the diagnostic accuracy of a hs-cTnT ≤14 ng/L measured ≥6 h a
The aim of this study was to investigate how solar drying setup and choice of juice pretreatment determine the drying flux in a fruit juice concentration process called solar assisted pervaporation. With this process, hygienic membrane pouches and solar energy are used to concentrate and preserve fruit juices. In this study, the feasibility of concentrating citrus (tangerine) juice into marmalade
Purpose: The incidence of colorectal cancer (CRC) varies by age, sex, and anatomical subsite. Few studies have examined the temporal trends of age-specific sex disparity in incidence and survival by age at diagnosis and anatomical site. Patients and Methods: The study was performed on all incident cases of CRC, using data derived from the nationwide Swedish Cancer Register between 1960 and 2014, i
We seek to identify factors that facilitate or inhibit transmission of drug abuse (DA) from high-risk parents to their children. In 44,250 offspring of these parents, ascertained from a Swedish national sample for having a mother and/or father with DA, we explored, using Cox models, how the prevalence of DA was predicted by potentially malleable risk factors in these high-risk parents, their spous
To date, there is no validated fluid biomarker for tau pathology in Alzheimer's disease, with contradictory results from studies evaluating the correlation between phosphorylated tau in CSF with tau PET imaging. Tau protein is subjected to proteolytic processing into fragments before being secreted to the CSF. A recent study suggested that tau cleavage after amino acid 368 by asparagine endopeptid
Cardiac arrest is the aprupt loss of cardiac function and circulation, follwed by the loss of consciousness and breathing. Most patients succumb before admission to hospital and survivors frequently suffer from anoxic-ischemic brain injury. The number of patients who survive with good neurological outcome, is low. In this thesis, we investigated the association of abnormal arterial partial pressur
Background: Currently, it is well known that the sound environment in intensive care units (ICU) is substandard. Therefore, there is a need of interventions investigating possible improvements. Unfortunately, there are many challenges to consider in the design and performance of clinical intervention studies including sound measurements and clinical outcomes. Objectives: (1) explore whether it is
Precision agriculture and Unmanned Aerial Vehicles (UAV) are revolutionizing agriculture management methods. Remote sensing data, image analysis and Digital Surface Models derived from Structure from Motion and Multi-View Stereopsis offer new and fast methods to detect the needs of crops, greatly improving crops efficiency. In this study, we present a tool to detect and estimate crop damage after
Exploratory testing (ET) is a test technique used to test software. It is a free way (compared to scripted test) of testing, where the tester takes notes during the test session. The tester has the option to select his own way when testing the software, he learns and tests at the same time. Notes are the result from the test session and are used to see what has been tested, e.g. the outcome and th
Rotterdamreglerna är en FN konvention med namnet: Förenta Nationernas konvention om avtal om internationell transport av gods helt eller delvis till sjöss. Bakom denna långa titel döljer sig det senaste försöket att reformera och harmonisera lagstiftning som reglerar godsbefordran till sjöss. Rotterdamreglerna blev underskrivna av ett antal länder 2009 i Rotterdam och kommer träda ikraft ifall de The Rotterdam Rules is a UN Convention with the name: United Nations Convention on Contracts for the International Carriage of Goods Wholly or Partly by Sea. Behind this long title hides the latest attempt to reform and harmonise the law governing carriage of goods by sea. The Rotterdam Rules were signed by a number of countries in 2009 in Rotterdam and will enter into force if they receive accept
This qualitative study is based on interviews with four different voluntary workers. The focus on this study is young voluntary workers inside the organization TAMAM. TAMAM is a voluntary organization with a focus on helping children with their homework, but also bounding relationships between children with different backgrounds. The main goal with this study was to find out how young voluntary wo
The European Union has decided to standardize the train control command system on the European railways. The reason for the standardization of the train control command system is to increase the competitiveness of the railway by promoting the ability to run the same train from one end of Europe to the other, without the need to change locomotives and drivers. The train control command system that
Våldtäkt är ett ord som väcker många känslor och associationer hos människor i dagens samhälle. Alla har på något sätt kommit i kontakt med det, även om han eller hon inte själv varit drabbad eller känner någon som har. Med jämna mellanrum är våldtäkt och sexuella övergrepp i stort ett stort och hett ämne i media. Tyvärr speglar inte alltid deras bild av hur det ser ut, den som finns i verkligheteRape is a word that arouses many feelings and associations of people in today's society. All have somehow come into contact with it, even if he or she has not personally been affected or knows someone who has. Periodically, the rape and sexual abuse in general is a great and hot topic in the media. I do not always reflect their view of how it looks in the real world. It's easy to think and
Under 2008 svarade EU:s offentliga upphandling för 17-18 procent av EU:s BNP. Huruvida offentliga medel skall kunna användas som instrument för att förverkliga politiska ambitioner eller om upphandlande myndighet endast skall ta hänsyn till ekonomiska aspekter har varit föremål för diskussion. Jag har valt att kartlägga de normgivande regelverk som reglerar arbetsrättslig hänsyn vid offentlig upphIn 2008 public procurement made up 17-18 percent of the EU GDP. The issue of whether the disbursement of public funds can be used to promote social objectives, including preservation of labour law requirements or whether public authorities only shall take economic considerations into account when deciding what to purchase, has been subject to discussion. In this thesis, I have chosen to describe t
Extreme events are believed to become frequent, intense and long lasting with climate change. An example of such extreme event is the record breaking summer 2003 heat wave. The 2003 heat wave, accompanied by drought conditions, had severe impacts on the European terrestrial ecosystems. In this study we have used an ecosystem model LPJ-GUESS to investigate how the carbon balance of Europe was affec
Frågan om hur man bör se på straffansvar och påföljder för personer som begår brott under inflytande av en allvarlig psykisk störning är omdebatterade och därtill mycket komplicerad. Intresset av att personer som begår brott möts av en adekvat reaktion på brottet ställs här emot behovet av att tillräckligt beakta gärningsmannens psykiska tillstånd och behov av behandling. Principen att vissa persoThe question of how one should look at penalties and sanctions for persons committing crimes under the influence of a serious mental illness is controversial and very complicated. The interest in that people who commit crimes are met with an adequate response to crime is put up against the need to sufficiently take into account the offender's mental condition and need for treatment. The princi
