Filetype
Objective: Subjective cognitive decline (SCD) is associated with an increased risk of Alzheimer's Disease (AD). Early disease processes, such as amyloid-β aggregation measured with quantitative PET, may help to explain the phenotype of SCD. The aim of this study was to investigate whether quantitative amyloid-β load is associated with both
Purpose:
Identify alternative to the current air transportation routes from supply units in Asia to European customers. The authors strive to provide the department of Supply Flow & Logistics with proposals of how they can reduce their costs and environmental effects connected to transportation. The authors also strive to display and evaluate the risk connected to a change in transp
Framställningen syftar till att belysa den svenska vårdnadslagslagstiftningen avseende bestämmanderätten vid gemensam vårdnad samt konsekvenserna av vårdnadshavares oförmåga att samarbeta i frågor som rör barns rätt till vård. Enligt svensk familjerätt är det bästa för barnet att stå under föräldrarnas gemensamma vårdnad samt att föräldrarna tar gemensamma beslut i alla frågor som rör barnet. NämnThe aim of this thesis is to analyse the current legislation regarding the right of decision under joint legal custody and the absence of legal rules in this area. The thesis furthermore analyses the consequences of the legal requirement of consensus between the parents for all decisions regarding the child, as well as the consequence of the parents inability to cooperate when it comes to the chil
Finansiell leasing är idag en etablerad form av finansiering vid anskaffning av egendom. Den finansiella leasingmarknaden i Sverige har sedan 2002 växt stadigt med i genomsnitt 10 procent per år. Trots finansiell leasings vida användning som finansieringsform åtnjuter nyttjanderätter till majoriteten av egendomstyper inte sakrättsligt skydd i svensk rätt. I enlighet med principen att köp bryter leFinancial leasing is an established form of funding the procurement of property. The financial leasing market in Sweden has since 2002 grown steadily by an average of 10 percent annually. Despite the wide use of financial leasing as financing form, the usufructs to a majority of properties are not rights in rem in Swedish law. In accordance with the principle of sale always breaks a right to use,
This study aimed to quantify and compare zooplankton feeding interactions in terms of diet composition, ingestion rate, and food size selectivity of a copepod (Acartia tonsa) and a cladoceran (Evadne nordmanni). This was achieved by surveying the grazing impact of A. tonsa and E. nordmanni on the natural phytoplankton, microzooplankton and microbial community occurring in autumn in coastal Skagera
The need of a European immigration policy within the EU appear to be evident. Until fairly recently, immigration and asylum policy was strictly the concern of every national state but since the mid-80s, a clear intensification of cooperation has taken place. The measures taken in this field the last 15 years have been concentrated on exclusion of foreigners. The Single European Act introduced an a
Background: Biomarker-based risk predictions of dementia in people with mild cognitive impairment are highly relevant for care planning and to select patients for treatment when disease-modifying drugs become available. We aimed to establish robust prediction models of disease progression in people at risk of dementia. Methods: In this modelling study, we included people with mild cognitive impair
Alzheimer’s disease is an aging related disorder of the mind, accountable for 60-80 percent of all cases of dementia. With its insidious progression and the decline of cognitive abilities, this disease is a major challenge for our society as a whole. This is because of the growing proportion of people living to advanced age and our current lack of capacity to prevent or even give effective symptom
Therapeutic antibodies are the fastest growing class of drugs but suffer from a crowded target-space where many antibodies, against a few targets, are developed in parallel. The aim of this thesis is to find methods to enable discovery of novel antibody-target combinations and thereby increase the target-space. A strategy to achieve this is to use phage display antibody libraries and selection on
The evaluation of satellite precipitation products (SPPs) at regional and local scales is essential in improving satellite-based algorithms and sensors, as well as in providing valuable guidance when choosing alternative precipitation data for the local community. The Tropical Rainfall Measuring Mission (TRMM) has made significant contributions to the development of various SPPs since its launch i
Background: Epilepsy patients commonly exercise less than the general population. Animal studies indicate beneficial effects of physical activity in established epilepsy, while its effect on the development is currently less known. Methods: Here, we investigated the incidence of epilepsy during 20 years in a cohort of participants from the long-distance Swedish cross-country ski race Vasaloppet (n
Agricultural intensification and associated loss of high-quality habitats are key drivers of insect pollinator declines. With the aim of decreasing the environmental impact of agriculture, the 2014 EU Common Agricultural Policy (CAP) defined a set of habitat and landscape features (Ecological Focus Areas: EFAs) farmers could select from as a requirement to receive basic farm payments. To inform th
The indigenista novel is a realistic novel with a strongly ideological character that was developed primarily in the Andean countries (Peru, Bolivia, Ecuador) during the first half of the 20th century with the purpose of making the reader aware of the living conditions of the indigenous Native American population. The overall aim of this study was to investigate the female characters in five of th
Popular Abstract in Swedish Cystisk fibros (CF) är en ärftlig sjukdom som orsakas av en defekt jonkanal. Denna defekt ger upphov till en onormal saltbalans i kroppen och följderna blir många. I lungorna och magtarmkanalen produceras ett väldigt segt slem vilket täpper till luftvägarna och medför andningssvårigheter. De slemfyllda lungorna klarar inte av att transportera upp slemmet och istället stCystic fibrosis is an inherited disease, caused by mutations of the cystic fibrosis transmembrane conductance regulator gene. The gene codes for a protein that serve as chloride channel. In cystic fibrosis, this protein is lacking or has a defect function resulting in a thick and sticky mucus of the airways. The altered airway environment promotes mucus and growth of pathogenic bacteria. A common
Background: The benefits of exercise in mild and moderate knee or hip osteoarthritis (OA) are apparent, but the evidence in severe OA is less clear. We recently reported that neuromuscular training was well tolerated and feasible in patients with severe primary hip or knee OA. The aims of this controlled before-and-after study were to compare baseline status to an age-matched population-based refe
Popular Abstract in Swedish Immunsystemet är ett invecklat och komplext system som finns överallt i kroppen och som inte är begränsat till ett enda organ. Vi utsätts hela tiden för ”angrepp” från mikro-organismer (t.ex. bakterier eller virus) men också för främmande ämnen som kan vara skadliga eller giftiga. Immunsystemets huvudfunktion är att hjälpa kroppen att känna igen dessa ”angripare” och atThe overall aim of this PhD project was to gain insight into the incidence of primary immunodeficiency (PID) in southern Sweden and to optimize diagnostic and treatment measures for these patients. We estimated the occurrence rate of PID in the pediatric population of southern Sweden during a period of 4 years and described the demographic, clinical and immunological characteristics of the identif
Greenhouses and nursery-gardens is an important business in Sweden, covering a land area of 3,0 million square meters in 2011. The downside of this otherwise blooming business is however the use of so called PPPs, plant protection products, which is connected to it. Historically the use of PPPs has been widespread and the handling has been conducted in an off-hand way. During the post-war time the
Popular science summary Hodgkin’s lymphoma (HL) is a common B cell lymphoma of the Western world and the therapies used to treat it have considerable side effects. Epstein Barr Virus (EBV) infection is associated with the pathogenesis of HL, though little is known about its contribution. B-lymphocyte undergoes two rounds of differentiation; first in the bone marrow where it becomes a Naïve B cell
Regler om budplikt infördes i NBK:s rekommendationer 1999. Efter en komplettering av takeover-direktivet blev det lag i LUA 2005. Företeelsen med budplikt på den svenska aktiemarknaden är således relativ ny, varför dess tillämpning och effekt är intressant att utreda. Budpliktsreglerna härstammar från Takeover Code i Storbritannien som uppstod efter att aktiemarknaden, under 1960-1970-talet, blev Mandatory bid rules were introduced in NBK´s recommendation in 1999, and then statutory in LUA in 2005, after an implementation of the takeoverdirective. The phenomenon with mandatory bid rules is therefore relatively new on the Swedish stock market why its application and impact is interesting to evaluate. Mandatory bid rules derives from the Takeover Code, from the UK, that emerged when the stoc
