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Objective: Oxidation of LDL plays a key role in the development of atherosclerosis. HDL may, in part, protect against atherosclerosis by inhibiting LDL oxidation. Overexpression of HDL-associated apolipoprotein M (apoM) protects mice against atherosclerosis through a not yet clarified mechanism. Being a lipocalin, apoM contains a binding pocket for small lipophilic molecules. Here, we report that
The impacts of climate change are likely to exacerbate many problems that coastal areas already face. In this study, we used multinomial logistic regression to examine human perception of climate change based on a cross-sectional survey of 1253 individuals in coastal regions of Tanzania. This was complemented with time series analysis of 50-year meteorological data. The results indicate that self-
The signaling mechanisms regulating neutrophil recruitment, systemic inflammation and T-cell dysfunction in polymicrobial sepsis are not clear. This study explored the potential involvement of the calcium/calcineurin-dependent transcription factor, nuclear factor of activated T-cells (NFAT) in abdominal sepsis. Cecal ligation and puncture (CLP) triggered NFAT-dependent transcriptional activity in
Objective. To investigate the impact on ICD coding behaviour of a new case-mix reimbursement system based on coded patient diagnoses. The main hypothesis was that after the introduction of the new system the coding of chronic diseases like hypertension and cancer would increase and the variance in propensity for coding would decrease on both physician and health care centre (HCC) levels. Design. C
Abstract Objective. Only a minority of patients with low-risk prostate cancer needs treatment, but the methods for optimal selection of patients for treatment are not established. This article describes the Study of Active Monitoring in Sweden (SAMS), which aims to improve those methods. Material and methods. SAMS is a prospective, multicentre study of active surveillance for low-risk prostate can
Nocturnal passerine migrants could substantially reduce the amount of energy spent per distance covered if they fly with tailwind assistance and thus achieve ground speeds that exceed their airspeeds (the birds' speed in relation to the surrounding air). We analysed tracking radar data from two study sites in southern and northern Scandinavia and show that nocturnally migrating passerines, during
The partitioning of Clavulanic Acid (CA) in a novel inexpensive and stable aqueous two-phase system (ATPS) composed by poly(ethylene glycol) (PEG) and sodium polyacrylate (NaPA) has been studied. The aqueous two-phase systems are formed by mixing both polymers with a salt (NaCl or Na2SO4) and an aqueous solution of CA. The stability of CA on the presence of both polymers was investigated and it wa
Background: Stroke in the young has not been thoroughly investigated with most previous studies based on a small number of patients from single centers. Furthermore, recent reports indicate that Fabry disease may be a significant cause for young stroke. The primary aim of our study was to determine the prevalence of Fabry disease in young stroke patients, while the secondary aim was to describe pa
Summary Background: The vitamin K-dependent Gas6 protein (product of growth arrest specific gene 6) binds to, and activates the TAM receptor tyrosine kinases Tyro3, Axl, and Mer. Gas6 and the TAM receptors have been suggested to be important for primary platelet functions, but Gas6 cannot be found in human platelets. However, Gas6 is present in human plasma at a concentration of around 0.2 nM, whi
Base cation weathering (BCw) rate is one of the most influential yet difficult to estimate parameters in the calculation of critical acid loads of nitrogen (N) and sulfur (S) deposition for terrestrial systems. Only the clay correlation-substrate method, a simple empirical model, has been used for estimating BCw rates for forest ecosystems in the conterminous USA and may not be suitable for applic
Backgrounds. A focus on psychiatric rehabilitation in order to support recovery among persons with severe mental illness (SMI) has been given great attention in research and mental health policy, but less impact on clinical practice. Despite the potential impact of psychiatric rehabilitation on health and wellbeing, there is a lack of research regarding the model called the Psychiatric Rehabilitat
Forskningsfrågor: Hur har tillitsbaserad styrning och ledning tillämpats i praktiken i en svensk gymnasieskola? Vilka upplevelser har de anställda på skolan av tillitsbaserad styrning och ledning och vad det har medfört i verksamheten? Syfte: Undersöka hur tillitsbaserad styrning och ledning kan tillämpas i praktiken i en svensk gymnasieskola och vilka upplevelser de anställda på skolan har av anResearch questions: How has trust-based governance been applied in practice in a Swedish upper secondary school? What kind of experiences does the employees at the school have of trust based governance and what it has entailed for the school activities. Purpose: Study how trust-based governance can be applied in practice in a Swedish upper secondary school and what kind of experiences the employe
Under våren 2022 genomförde anställningsskyddslagen en förändring och den svenska arbetsrätten anses vara reformerad. En förändring av den svenska arbetsrätten har inte varit så omfattande sedan anställningsskyddslagen infördes 1973. Arbetsmarknaden präglas av kraven på flexibilitet och rörlighet samtidigt som anställningsskyddet behöver vara en trygghet för arbetstagare. Den svenska arbetsmarknadIn the spring of 2022, the Employment Protection Act implements a change and Swedish labor law is considered reformed. The transformation of Swedish labor law has not been as extensive since the introduction of the Employment Protection Act in 1973. The labor market is characterized by demands for flexibility and mobility, while employment protection needs to provide security for employees. The Sw
This master’s thesis explores the sustainability and the circularity of industrial packaging of components for complex electronic products. The research aims to gain insight into the structure of the packaging system between the suppliers and the manufacturers (EMS) and evaluate its circularity to identify the opportunities and challenges for future improvement. The study examines the packaging
This master’s thesis explores the sustainability and the circularity of industrial packaging of components for complex electronic products. The research aims to gain insight into the structure of the packaging system between the suppliers and the manufacturers (EMS) and evaluate its circularity to identify the opportunities and challenges for future improvement. The study examines the packaging fo
Since 1956, the Eurovision Song Contest (ESC) has become one of the most popular entertainment events in the world. Each year, countries across Europe compete in a competition with original songs. While the majority of the entries includes a notion of European or national identity, there have been various performers from minority communities throughout the years. This thesis aimed to study the per
How do we know that the food we eat is safe and healthy? Sweden is high on the charter over countries which have the highest food safety standards. Food health inspectors play an absolutely crucial role in maintaining these standards and systems. By inspecting food processing facilities, restaurants, and other food establishments they help prevent the spread of foodborne illnesses and help pro
Pramipexole is a medication that normalises dopamine signalling in the brain. Previous studies have suggested that pramipexole is an effective treatment option for depression and anhedonia because it targets the dopaminergic pathways within the brain’s reward network. The nucleus accumbens is a crucial region for dopamine signalling in reward processing. Both task-based and resting-state fMRI evid
The purpose of this master's thesis is to study how the public library can contribute to the transition into a more sustainable, resilient society. Through the phenomenon of the seed library, this thesis examines the library's ability to engage and communicate with the local community about environmental and climate related issues. The following questions were addressed: (1) Which function
One of the main qualities of life in Icelandic society is the earth’s heat that has been harnessed and fed into the homes of the citizens. The swimming pool is the clearest and most visible manifestation of these qualities of life. Bathhouses are a regular part of many people’s daily lives, and human life in the pools is a fascinating part of Icelandic society. Architecture plays a key role there,
