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Popular Abstract in Swedish Hur kommer det sig att liknande reformprogram återfinns i olika länder? Varför väljs vissa idéer framför andra? Avhandlingen syftar till att öka förståelsen av så kallad policydiffusion, spridning av olika typer av policy, och den dynamik som omgärdar spridningen. Detta görs genom att undersöka hur externa, eller utländska, idéer integreras och översätts i en ny omgivniSimilar policies may be found in different countries. This, in turn, is an indication that policies travel. But why are certain policies imitated while others are not? The author seeks to further our understanding of policy diffusion and its dynamics by investigating how foreign ideas are integrated and translated into new contexts, and how these imported ideas influence national policymaking and

The timing of the ice margin retreat of the Late Glacial Patagonian Ice Sheet (PIS) in southern Patagonia has been the object of discussion for many years. In order to resolve questions about the complex response of the PIS to past climate change, any geological interpretation and data modelling need evaluation against an absolute chronology. The aim of this project is to investigate the applicabi

Background: Age, gender and socioeconomic status have been shown to be associated with the use of prescription drugs, even after adjustment for multimorbidity. General practitioners have a holistic and patient-centred perspective and our hypothesis is that this may reflect on the prescription of drugs. In Sweden the patient may seek secondary care without a letter of referral and the liability of

Around 70,000 osteoporosis-related fractures occur in Sweden annually and approximately half of the women in western world will sustain a fragility fracture after the age of 50 years. Fracture preventive efforts require the identification of individuals who are at high risk. Biochemical markers of bone turnover (BTMs) have shown some degree of fracture predictability. There is also a correlation b

Background: We have previously reported that expression of the RNA-and DNA-binding protein RBM3 is associated with a good prognosis in breast cancer and ovarian cancer. In this study, the prognostic value of immunohistochemical RBM3 expression was assessed in incident cases of malignant melanoma from a prospective population-based cohort study. Methods: Until Dec 31(st) 2008, 264 incident cases of

Acute myocardial infarction (AMI) can progress to heart failure, which has a poor prognosis. Normally, 60% of stroke volume (SV) is attributed to the longitudinal ventricular shortening and lengthening evident in the atrioventricular plane displacement (AVPD) during the cardiac cycle, but there is no information on how the relationship changes between SV and AVPD before and after AMI. Therefore, t

Glyoxalase I (GlxI) is an important enzyme that catalyzes the detoxification of methylglyoxal (MG) with the help of glutathione (H-SG). It is currently unclear whether MG and H-SG are substrates of GlxI or whether the enzyme processes hemithioacetal (HTA), which is nonenzymatically formed from MG and H-SG. Most previous studies have concentrated on the latter mechanism. Here, we study the two-subs

To prevent diseases arising from exposure to toxic metals, more knowledge about their temporal changes is needed, especially in children, the most vulnerable group. This study follows temporal changes in blood lead (BPb), mercury (BHg) and cadmium (BCd) levels in schoolchildren (8–11 years old) from two cities in southern Sweden. One blood sample per 773 children was used for time trend analyses b

BACKGROUND: Sotalol and dronedarone are both used for maintenance of sinus rhythm for patients with atrial fibrillation. However, while sotalol requires initial monitoring for QT prolongation and proarrhythmia, dronedarone does not. These treatments can be used in comparable patients, but their safety and effectiveness have not been compared head to head. Therefore, we retrospectively evaluated th

This thesis is a comparative analysis of five cases, in which criminal responsibility and mental disorder were in issue. Andrea Yates drowned her five children. John W. Hinckley Jr shot and injured President Ronald Reagan. Kjeldsen raped and assassinated a taxi driver on his way from Calgary to Banff. Mijailo Mijailovic attacked and killed the Swedish minister of foreign affairs Anna Lindh. Sara S

Since the earliest economic historical studies wage series have been used to sketch economic development both at the macro and the household level. This dissertation takes advantage of new data from women and men, working in both the countryside and in towns, as well as employed both by the day and on long-term contracts, in order to make an in-depth quantitative look at the relationships between

Popular Abstract in Swedish Antikroppar är viktiga beståndsdelar av det naturliga immunförsvaret som skyddar oss mot smittämnen, såsom bakterier och virus. Utvecklingen av olika genetiska och biokemiska teknologier har dessutom möjliggjort användningen av antikroppar för en mängd ändmål, bl a för diagnostik och behandling av infektionssjukdomar och cancer. I denna avhandling, som bygger på fem vetAntibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. Despite tremendous advances in all fields

The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. At low concentrations of denaturant the transition state occurs early in the folding reaction, whereas at high denaturant concentration it moves close to the nati

Popular Abstract in Swedish Avhandlingen är en studie av kvinnors brevskrivning i Sverige under 1700-talet. Breven är skrivna av ett antal kvinnor från de högre samhällsskikten (adel och borgerskap) under 1780- och 1790-talen. Flertalet av breven är skrivna på svenska, men några också på franska. Huvudsyftet med avhandlingen är att undersöka relationen mellan idén om att kvinnor skrev annorlunda, This dissertation is a study of women's letter-writing in eighteenth-century Sweden. The letters are written by a number of women from the uppper classes (nobility and bourgeoisie) during the last two decades of the eighteenth century. The majority of the letters are written in Swedish, some however in French. The main aim is to examine the relationship between the idea of women as a special kind

BACKGROUND: Health workers' (HWs') perspectives on the quality of maternal and newborn care (QMNC) are not routinely collected. In this cross-sectional study, we aimed to document HWs' perspectives on QMNC around childbirth in 12 World Health Organization (WHO) European countries.METHODS: HWs involved in maternal/neonatal care for at least one year between March 2020 and March 2023 answered an onl

In older adults, age-related degenerative processes and disorders often degrade some sensory systems more than others, which can make postural control disproportionally dependent on one kind of sensory information. The study aims were to investigate 1) the postural stability when healthy older adults were repeatedly exposed to a video in an immersive virtual reality (VR) environment, and 2) the re

Bacterial exopolysaccharides (EPS) have emerged as one of the key players in the field of heavy metal-contaminated environmental bioremediation. This study aimed to characterize and evaluate the metal biosorption potential of EPS produced by a novel Psychrobacillus strain, NEAU-3TGS, isolated from an iron ore deposit at Tamra iron mine, northern Tunisia. Genomic and pan-genomic analysis of NEA

BACKGROUND: People with intellectual disabilities (ID) are known to have a higher risk for a wide range of health conditions compared to the general population. However, there is little research comparing a more comprehensive range of diseases and conditions at different ages. Therefore, the aim of this study was to explore the overall age-specific diagnostic pattern among people with ID compared

Background: The accelerating global ageing phenomenon has given rise to a growing concern regarding cognitive decline in older adults. Research shows that spouse health is closely linked to individual well-being, as the physical and emotional health of one partner significantly affects the other. Although the connection between spousal health and older adults’ cognitive function has been recognize

This dissertation examines the construction of monumental synagogues in nineteenth-century Sweden as a means through which Jewish communities articulated public presence, negotiated belonging, and translated aspirations for civic inclusion into durable architectural form. Focusing on five purpose-built synagogues in Gothenburg (1855), Norrköping (1858), Stockholm (1870), Karlstad (1899), and Malmö