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NKT cells m the mouse recognize antigen in the context of the MHC class I-like molecule CD1d and play an important role in peripheral tolerance and protection against autoimmune and other diseases NKT cells are usually activated by CD1d-presented lipid antigens However, peptide recognition m the context of CD 1 has also been documented, although no self-peptide ligands have been reported to date H

Aims: To assess changes in access to highly active antiretroviral therapy (HAART) between the end of 2002 and the end of 2005, and to review the capacity for further HAART scale-up in the then 52 Member States of the WHO European Region. Methods: Analysis of data from four surveys evaluating access to HAART, supplemented by regional estimates of the number of people receiving HAART. Changes in acc

Objective . Hypoglycaemia is regularly accompanied by hypovolaemia. To suggest a mechanism for this phenomenon, we reviewed data from eight studies conducted by our group and examined the circumstances under which rebound hypoglycaemia develops after intravenous infusion of glucose solutions. Material and methods. Forty healthy volunteers and 40 patients received a total of 122 infusions of glucos

Molecular sensing in the lingual mucosa and in the gastro-intestinal tract play a role in the detection of ingested harmful drugs and toxins. Therefore, genetic polymorphisms affecting the capability of initiating these responses may be critical for the subsequent efficiency of avoiding and/or eliminating possible threats to the organism. By using a tagging approach in the region of Taste Receptor

Objectives: What is the prognostic significance of achieving a systolic blood pressure of <140 mmHg? Setting: Diabetic renal policlinic, university hospital of Lund, Sweden. Subjects: 118 type 2 diabetic patients with micro-macroalbuminuria were followed for four years (range 1-8 years). Method and main outcome measures: The prognostic significance of office, day- and nighttime measurements of blo

A biosensor, based on a redoxactive osmium polymer and sulfite oxidase on screen-printed electrodes, is presented here as a promising method for the detection of sulfite. A catalytic oxidative current was generated when a sample containing sulfite was pumped over the carbon screen-printed electrode modified with osmium redox polymer wired sulfite oxidase. A stationary value was reached after appro

Neuropeptide Y (NPY) has been implicated in anxiolytic- and antidepressant-like behaviour as well as seizure-suppressant effects in rodents. Although these effects appear to be predominantly mediated via other NPY receptors (Y1 and/or Y2), several studies have also indicated a role for Y5 receptors. Gene therapy using recombinant viral vectors to induce overexpression of NPY, Y1 or Y2 receptors in

We have investigated the structure of a microbial community in semi-natural sandy grassland in southeast Sweden. The sand is rich in lime, but in most places the soil is decalcified in the upper layers, and therefore this site shows a large variation in pH within short distances. We collected samples at three different soil depths (0-10 cm, 10-20 cm and 20-30 cm) and found the pH to range from 5 t

Strandberg R., Hake M., Klaassen R.H.G. & Alerstam T. 2012. Movements of immature European Honey Buzzards Pernis apivorus in tropical Africa. Ardea 100: 157-162. Immature European Honey Buzzards Pernis apivorus are believed to remain in tropical Africa during the first years of their lives. We studied their movements during this period with the aid of satellite telemetry. After crossing the Sa

PURPOSE: In recent years, there has been an increasing interest in flattening-filter free (FFF) beams. However, since the removal of the flattening filter will affect both the mean and the variance of the energy spectrum, current beam-quality specifiers may not be adequate for reference dosimetry in such beams. The purpose of this work was to investigate an alternative, more general beam-quality s

BACKGROUND: There was a decrease 1982-2001 in smoking during early pregnancy in Swedish women. We sought to determine whether there was a parallel decrease in socio-economic inequality in smoking. METHODS: Registry data indicating educational level and smoking status at first antenatal visit in all 2,022,469 pregnancies in Sweden 1982-2001 was analysed. Prevalence differences, odds ratios based on

Dendroclimatic investigations of subfossil Scots pine (Pinus sylvestris) from two raised bogs in southern Sweden yielded a continuous floating 1492-year long tree-ring record. By cross-dating with bog-pine chronologies from Lower Saxony, Germany, the South Swedish record was assigned an absolute age of 5219-3728 BC. The cross-match between ring-width chronologies from these two regions, separated

Multiple factors contribute to the pathogenesis and prognosis of chronic obstructive pulmonary disease (COPD), still requiring new therapeutic strategies and medications for the disease. The aim of the present study is to investigate the model of lipopolysaccharide (LPS)-induced chronic lung injury and hyperinflation and test therapeutic effects of peroxisome proliferator-activated receptor (PPAR)

Senior lecturer Contact details Email: kes [dot] mccormick [at] iiiee [dot] lu [dot] se Phone: +46 46 222 02 56 Mobile: +46 72 223 12 27Organisation The International Institute for Industrial Environmental Economics Service point: 53 WebpageKes Mccormicks profile in Lund University research portalOther affiliations Profile area member LU Profile Area: Nature-based future solutions Associate profes

https://www.iiiee.lu.se/kes-mccormick - 2026-05-08

Endo-beta-1,4-D-mannanase is the key depolymerizing enzyme for beta-1,4-mannan polymers present in the cell walls of plants and some algae, as well as in some types of plant seeds. Endo-1,4-beta-mannanase from blue mussel Mytilus edulis (MeMan5A) belongs to the glycoside hydrolase (GH) family 5 enzymes. The MeMan5A structure has been determined to 1.6 angstrom resolution using the multiple-wavelen

This report is about the co-operation between the police and the social services in the specific situation when the social services apply for assistance for taking children and drug-abusers in to involuntary care immediately. The police have an authority to use violence that social workers do not have. Therefore social workers need the police to accomplish this task. The report aims to reach adeep

The growth of ultrathin ZrO2 films on Si(100)-(2 x 1) and Si(111)-(7 x 7) has been studied with core level photoelectron spectroscopy and X-ray absorption spectroscopy. The films were deposited sequentially by chemical vapor deposition in ultra-high vacuum using zirconium tetra-tert-butoxide as precursor. Deposition of a > 50 angstrom thick film leads in both cases to tetragonal ZrO2 (t-ZrO2), whe

MAPKs (mitogen-activated protein kinases) are signalling components highly conserved among eukaryotes. Their diverse biological functions include cellular differentiation and responses to different extracellular stress stimuli. Although some substrates of MAPKs have been identified in plants, no information is available about whether amino acids in the primary sequence other than proline-directed

Intestinal spirochetes (Brachyspira spp.) are causative agents of intestinal disorders in animals and humans. Phylogenetic analysis of cloned 16S rRNA genes from biopsies of the intestinal mucosa of the colon from two Swedish 60-years old adults without clinical symptoms revealed the presence of intestinal spirochetes. Seventeen clones from two individuals and 11 reference strains were analyzed an