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Muskelsjukdom

Malign hypertermikänslighet Malign hypertermikänslighet (malign hypertermi MH) är en ärftlig muskelåkomma, där narkos kan utlösa en potentiellt dödande ökning av ämnesomsättningen. Utredning sker huvudsakligen med hjälp av en öppen muskelbiopsi, i vissa fall med mutationsdiagnostik. MH enheten i Lund är ett nationellt centrum. Vår forskning har två huvudinriktningar Genetik: Vi har samarbete meMalign hypertermikänslighet Malignant hyperthermia is a hereditary muscle disease, which can be triggered by anesthesia. This may result in a potentially life-threatening increase in the metabolism. Evaluation of the patients occurs mainly through muscle biopsi, sometimes with mutation diagnostica. The MH unit i Lund is a national centra. The reasech can be divided in 2 parts: Genetic: The aim o

Development of a concept for a SmartCashCenter

A trend, which can be noted in the field of cash handling, is the increase of ATMs that are able to recirculate banknotes. Cash recycling means that notes deposited by one customer are then available for withdrawal by another from the same machine. Cash recycling has both economic advantages and reduces environment impact, as transport to machines for filling and emptying them can be decreased. Wh

Artificial spatiotemporal touch inputs reveal complementary decoding in neocortical neurons

Investigations of the mechanisms of touch perception and decoding has been hampered by difficulties in achieving invariant patterns of skin sensor activation. To obtain reproducible spatiotemporal patterns of activation of sensory afferents, we used an artificial fingertip equipped with an array of neuromorphic sensors. The artificial fingertip was used to transduce real-world haptic stimuli into

Minimalinvasiv hjärtkirurgi vid hjärtklaffsjukdom

Minimalinvasiv hjärtkirurgi definieras som hjärtkirurgiska operationstekniker där man avstår från en full median sternotomin (längsgående delning av hela bröstbenet). Hjärtoperationen sker då istället med alternativa exponeringstekniker under det att man använder konventionell hjärt-lungmaskin. Beroende på diagnos utförs antingen operationen med video-assisterad, eller robot-assisterad, endoskopi Minimally invasive cardiac surgery is defined a cardiac surgery with heart-lung machine, but without full median sternotomy. Depending on the underlying disease the surgical procedures can be performed through a 4-6 cm mini-thoracotomy on the right side with either video-assisted or robotic-asssited endoscopy or through a partial split of the sternum. We believe that minimally invasive facilitate

Barninfektioner och global barn- och ungdomshälsa

Forskargruppen "Barninfektioner och global barn- och ungdomshälsa" främjar forskning och utbildning. Det primära forskningsområdet är pediatrik och mer specifika inom området barninfektioner, Kawasakis sjukdom, global barn och -ungdomshälsa samt migration. Forskargruppen samarbetar med andra forskargrupper både nationellt och internationellt. Forskargruppen är involverad i utbildningen av läkarsPediatric infectious diseases and global child health is a research group promoting high quality research and education. The primary area of research is Pediatrics and more specific in the field of infectious diseases, Kawasaki disease, global child health and migration. The research group collaborates with research teams both nationally and internationally as well as being involved in the educa

Enheten för klinisk suicidforskning

Varje år tar cirka 1500 personer sitt liv i Sverige. Det är en minskning sedan 1980-talet men de senaste femton åren har minskningen stannat av. Enheten för klinisk suicidforskning arbetar med olika områden inom suicidforskning med det övergripande syftet att bättre förstå hur suicid kan förebyggas. •Område A: Psykopatologi och riskfaktorer för patienter med risk för framtida suicid. Vi undersökeSuicide research is of importance to find new strategies to prevent suicide. Each year approximately 800 000 people in the world, and 1500 people in Sweden commit suicide. The suicide rate has not decreased over the last 15 years. The Unit for Clinical Suicide Research cover different areas within this field. • Area A: Psychopathology and risk factors. Our group investigates how psychopathology

S100B protein levels in saliva: correlation with gestational age in normal term and preterm newborns

Objectives: S100B is an acidic calcium-binding protein of the EF-hand family present in the central nervous system, where it is concentrated in glial cells. It has been suggested to act as a cytokine with neurotrophic effects at physiological concentrations. Design and methods: S100B concentration was assessed in saliva by western blot analysis and an immunoluminometric assay. A reference curve of

From major amputation to prosthetic outcome: A prospective study of 190 patients in a defined population that underwent major amputation

In this prospective study, the overall treatment and outcome of patients that underwent major lower limb amputation in a defined population is described. The study was performed over a five year period in the Health Care District of North-East Skåne, Sweden. Some 190 patients, permanent inhabitants of the Health Care District, underwent major lower limb amputation. Sixteen (16) of these patients h

Diabetes - kardiovaskulär sjukdom

We challenge the question of how environmental (diet, physical activity, alcohol) factors modify genetic associations put forward by us and others, in recent genome wide association studies (GWAS) of lipoprotein traits, cardiovascular disease (CVD) and obesity and aim to utilize this information in intervention studies and in development of prediction models. We work to further improve genetic C

Biomarkörer vid hjärnsjukdomar

Our main focus is understanding peripheral pathology in HD and investigate its importance for disease pathogenesis and biomarkers. Our work is based on the hypothesis that insights into peripheral pathology in HD will improve knowledge of key pathogenic mechanisms, possibly providing new biomarkers and novel therapeutic targets.

Enheten för translationell obstetrisk forskning

Preeklampsi är ett allvarligt graviditetsrelaterat tillstånd som årligen drabbar 10 miljoner kvinnor världen över. Etiologin är ännu okänd och diagnosen ställs baserad på moderns kliniska symptom: högt blodtryck och någon organpåverkan som debuterar efter 20 veckors graviditet. För närvarande är förlossning den enda ”boten”. Preeklampsi medför en ökad långsiktig risk för utveckling av hjärt-kärlsjPreeclampsia is a severe pregnancy-related condition that annually affects 10M women worldwide. The etiology is largely unknown and diagnosis is currently based on maternal clinical symptoms: high blood pressure and organ damage manifesting after 20 weeks of gestation. Delivery is currently the only cure. Increased long-term risk for cardiovascular diseases and stroke after preeclampsia point to i

Medicinska fakultetens centrum för undervisning och lärande, MedCUL

MedCUL är Medicinska fakultetens Centrum för Undervisning och Lärande. Vi erbjuder kompetensutveckling inom undervisning och lärande. Vi verkar för att utformning av, beslut om och genomförande av utbildning ska vila på aktuellt internationellt kunskapsläge inom utbildningsområdet.MedCUL coordinates the faculty's quality assurance work at undergraduate level in cooperation with educational committees and program directors. We collaborate with teachers and educational leaders in developmental projects. Our research in medical education concerns areas related to our practice such as Problem Based Learning (PBL), workplace learning and supervision, PhD student supervision and