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Cognitive function and cardiovascular disease in relation to hypertension and adaptive behavior in the serial Color Word Test. Results from population study "Men born in 1914" in Malmö, Sweden.

Popular Abstract in Swedish "Män födda 1914" är en studie som påbörjades 1982 för att studera hjärt- och kärlsjukdomar. Studien bedrivs vid Institutionen för samhällsmedicin vid Universitetssjukhuset MAS. Alla män, födda jämn månad 1914 och bosatta i Malmö, inbjöds att deltaga. Totalt inbjöds 621 män, då 68 år gamla, och av dessa deltog 500. Då man jämförde deltagare med icke-deltagare kunde man k"Men born in 1914" is a prospective cohort study on the epidemiology of cardiovascular disease. The study is run by the Department of Community Medicine, Lund University, Malmö. Five hundred men participated in the study when it started with a baseline examination in 1982/83. The men were then 68 years old. The psychological part of the study included tests of cognitive function and the serial Col

Detection of HCl in a Premixed CH4/O-2/Ar Flame Seeded with CHCl3 Using Mid-IR Polarization Spectroscopy

Mid-infrared polarization spectroscopy (IRPS) was applied to detect HCl in flames. For the first time, sensitive and nonin trusive HCl detection with a manner of high spatial- and temporal-resolution in harsh reactive gas flow has been demonstrated in this work. In an atmospheric pressure premixed CH4/O-2/Ar flat flame, trace level HCl was prepared by seeding small amount chloroform through the Ar

Swelling and Mechanical Properties of Polymer Gels: Salt, Macroion and Network Topology Effects

Popular Abstract in Swedish Ordet polymer användes första gången av Berzelius år 1830 och kommer ursprungligen från grekiskans polymeres, vilket betyder av flera delar ("poly"=flera och "meros"=del). En polymer är en lång molekyl gjord av flera upprepande enheter. Polymerer finns i naturen (t. ex. DNA och proteiner) men kan också tillverkas genom syntetiska processer. Om polymeren innehåller laddaThe work in this thesis concerns polymer gels, especially their swelling and mechanical properties modelled using a coarse-grained model of polyelectrolytes. The method used to study polymer gels was molecular simulation utilising the simulation package MOLSIM. Particular focus is on the effect of salt, macroions and network topology effects (polydispersity, loose-ends and interpenetrating network

Fertility and female dietary exposure to persistent organochlorine compounds

Popular Abstract in Swedish Polyklorerade bifenyler (PCB) är ett samlingsnamn för ett antal kemiska föreningar. De utmärker sig genom att de har en god elektrisk isoleringsförmåga och tålighet för höga temperaturer, och de har därför använts i bl.a. transformatorer och kondensatorer men även som mjukgörare i plaster och färger. Sedan det visat sig att exponering för PCB innebar allvarliga hälsoeffPersistent organochlorine compounds (POC), such as polychlorinated biphenyls (PCB) and dioxins, are long-lived and highly lipophilic compounds which are present in all biota today. In Sweden, one of the major exposure routes for POC is through the consumption of fatty fish from the Baltic Sea, which is off the east coast of Sweden, and one of the most highly exposed populations is the fishermen's

Makt och människor : europeisk statsbildning från medeltiden till franska revolutionen

State formation in Europe and, more precisely, the nature and development of the early modern type of state, is the focus of this book. The study of state formation has, in recent years, been heavily influenced by the works of Charles Tilly and his followers, who stress international military competition as the driving force in the development of the European states and state system, creating stro

Proteomics of PTI and Two ETI Immune Reactions in Potato Leaves

Plants have a variety of ways to defend themselves against pathogens. A commonly used model of the plant immune system is divided into a general response triggered by pathogen-associated molecular patterns (PAMPs), and a specific response triggered by effectors. The first type of response is known as PAMP triggered immunity (PTI), and the second is known as effector-triggered immunity (ETI). To ob

VEGF synthesis and VEGF receptor 2 expression in patients with bronchiolitis obliterans syndrome after lung transplantation

OBJECTIVES: Chronic lung allograft dysfunction including Bronchiolitis obliterans syndrome (BOS) is common after lung transplantation. Histologically, BOS is recognized as fibrotic lesions with accumulated extracellular matrix (ECM) in small airways. Lung fibroblasts are major producers of ECM and vascular endothelial growth factor (VEGF). In this study we hypothesize that VEGF is involved in BOS

IDENTIFYING DIFFERENTIATING FEATURES BETWEEN NORMAL AND TORN ROTATOR CUFF TENDONS USING FOURIER TRANSFORM INFRARED SPECTROSCOPY

Background: Up to one third of adults have been estimated to have rotator cuff tendon (RCT) tears. Larger RCT tears are associated with poorer scores and function, and are more likely to re-rupture after surgical repairs, hence there is a need for earlier identification and treatment. The aim of this study was to identify biomarkers of RCT tear pathologies to aid accurate identification and monito

Minorities in Yemen Reality and Challenges

Yemen is home to religious and sectarian minorities who represent about 0.5% of the total population. In addition to Muslims, there is a minority of Jews, who’s presence has drastically shrunk over the years due to the multiple violations and displacement they were subjected to. Yemen also has a Bahai minority, who are currently estimated to number around 2,000 individuals. They also have been sub

Long term outcome after treatment of de novo coronary artery lesions using three different drug coated balloons

Objective: To evaluate the long-term efficacy of three currently available drug coated balloons (DCB) for the treatment of de-novo coronary lesions. Methods: This was a retrospective analysis of prospectively collected data from the Swedish Coronary Angiography and Angioplasty Registry. Between 2009 and 2017, three currently available DCB brands used in the treatment of de novo lesions were includ

Lateral gene transfer and gene duplication played a key role in the evolution of mastigamoeba balamuthi hydrogenosomes

Lateral gene transfer (LGT) is an important mechanism of evolution for protists adapting to oxygen-poor environments. Specifically, modifications of energy metabolism in anaerobic forms of mitochondria (e.g., hydrogenosomes) are likely to have been associated with gene transfer from prokaryotes. An interesting question is whether the products of transferred genes were directly targeted into the an

Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE ε4, sex and age

It is unknown how neuroinflammation may feature in the etiology of Alzheimer's disease (AD). We profiled acute phase response (APR) proteins (α1-antitrypsin, α1-antichymotrypsin, ceruloplasmin, complement C3, ferritin, α-fibrinogen, β-fibrinogen, γ-fibrinogen, haptoglobin, hemopexin) in CSF of 1291 subjects along the clinical and biomarker spectrum of AD to investigate the association between infl

Identifying normal mammograms in a large screening population using artificial intelligence

Objectives: To evaluate the potential of artificial intelligence (AI) to identify normal mammograms in a screening population. Methods: In this retrospective study, 9581 double-read mammography screening exams including 68 screen-detected cancers and 187 false positives, a subcohort of the prospective population-based Malmö Breast Tomosynthesis Screening Trial, were analysed with a deep learning–b

Reporting frequency of radiology findings increases after introducing visual rating scales in the primary care diagnostic work up of subjective and mild cognitive impairment

Objectives: Study the effect of introducing a template for radiological reporting of non-enhanced computed tomography (NECT) in the primary care diagnostic work up of cognitive impairment using visual rating scales (VRS). Methods: Radiology reports were assessed regarding compliance with a contextual report template and the reporting of the parameters medial temporal lobe atrophy (MTA), white matt

His Bundle and Left Bundle Pacing in Pediatrics and Congenital Heart Disease : A Single Center Experience

Long-term right ventricular pacing is associated with left ventricular dysfunction and cardiomyopathy, particularly in pediatric patients and those with congenital heart disease (CHD). Research has shown that pacing-induced cardiomyopathy can be reversed with nonselective or selective His bundle pacing in adults, however, the information available about the use of this type of therapy in pediatric

Anti-rheumatic treatment and prosthetic joint infection : An observational study in 494 elective hip and knee arthroplasties

Background: Surgical site infections are more frequent among patients with rheumatic disease. To what extent this is related to immunosuppressive antirheumatic drugs is unclear, as is the value of discontinuing medication perioperatively. The aim of study was to assess the rate of surgical site infections after knee and hip replacement in patients with inflammatory joint disease, with an emphasis

Development of a polygenic risk score to improve screening for fracture risk : A genetic risk prediction study

BACKGROUND: Since screening programs identify only a small proportion of the population as eligible for an intervention, genomic prediction of heritable risk factors could decrease the number needing to be screened by removing individuals at low genetic risk. We therefore tested whether a polygenic risk score for heel quantitative ultrasound speed of sound (SOS)-a heritable risk factor for osteopo

Height, body mass index and prostate cancer risk and mortality by way of detection and cancer risk category

Obesity is a risk factor for advanced, but not localised, prostate cancer (PCa), and for poor prognosis. However, the detection of localised PCa through asymptomatic screening might influence these associations. We investigated height and body mass index (BMI) among 431 902 men in five Swedish cohorts in relation to PCa risk, according to cancer risk category and detection mode, and PCa-specific m

Estimated effect of secondary screening for hip dislocation

Objectives: To quantify the effect of secondary screening for hip dislocations. Design: Retrospective analysis of hospital files from participants in a prospectively collected nationwide registry. Setting: Child healthcare centres and orthopaedic departments in Sweden. Participants: Of 126 children with hip dislocation diagnosed later than 14 days age in the 2000-2009 birth cohort, 101 had complet

Reversal Treatment in Oral Anticoagulant-Related Intracerebral Hemorrhage—An Observational Study Based on the Swedish Stroke Register

Introduction: Intracerebral hemorrhage (ICH) is the most serious adverse effect of oral anticoagulant (OAC) treatment. The effect of OAC reversal therapy on outcome is uncertain. We compared 90-day survival and functional outcome in patients with OAC-ICH who received OAC reversal therapy with those who did not. Methods: Data from The Swedish Stroke Register (Riksstroke) for all registered cases of