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Although COPD is a major disease worldwide there is a perplexing current uncertainty about the nature of this disease. COPI) is characterized at onset and prevalently by the involvement of the lungs and bronchi, but as the disease evolves abnormalities develop in other organs and systems and the question arises: what is the pathogenesis of these respiratory and systemic impairments? Are the altera
CCND1 amplification results in cyclin D1 overexpression. However, other unidentified genetic mechanisms contribute to enhanced gene expression. In the present study, 32 squamous cell carcinoma of the head and neck (SCCHN) were investigated regarding chromosomal abnormalities involving 11q13 by cytogenetic analysis, genomic CCND1 amplification by differential PCR and FISH, and cyclin D1 expression
Annually laminated (varved) sediments from the River Angermanalven, mid-central Sweden, have been used to construct an annual 2000-year long record of varve thickness. Maximum daily annual discharge and mean varve thickness for the years 1909-1971 are significantly correlated (r = 0.87). A relationship between maximum daily annual discharge for the observed period (1909-1971) and varve thickness w
OBJECTIVES: To describe the drug use in epilepsy and Parkinson's patients living in nursing homes and to evaluate the impact of multi-speciality team intervention on health-related quality of life, activities of daily living (ADL) and confusion state. METHODS: Nursing home residents with epilepsy or Parkinson's disease in the county of Skåne in Sweden were identified. From 119 nursing homes, 262 p
The molecular self-diffusion in concentrated aqueous mixtures based on an oppositely charged po ymer-surfactant pair has been investigated by NMR pulsed field gradient techniques. The investigated structures were an ordered cubic Pm3n phase (ca. 50 wt % water) and a disordered micellar phase, both containing cetyltrimethylammonium (CTA(+)) micelles with mixed acetate (Ac-) and polyacrylate (PA(-))
Aims: To explore the prevalence of overweight in men and women in a Swedish rural community and to examine its associations with all-cause mortality. Methods: A community-based cohort study. A total of 1,109 men and women aged ≥40 years participated in a survey of cardiovascular disease (CVD) risk factors in the city of Skara in Skaraborg, Sweden, in 1993—94. Overweight was defined as a BMI≥25.0 k
Magnetic and related properties of rocks and products from oxidation of sulphide minerals have been investigated with magnetisation measurements (rocks and oxidation products), magnetic force microscopy (rocks), scanning electron microscopy (rocks and oxidation products), transmission electron microscopy (oxidation products), Mössbauer spectroscopy (oxidation products) and powder X-ray diffraction
Benzimidazole units have been grafted onto a polysulfone (PSU) backbone via long alkyl thio–ether chains using a two-step procedure. In the first step, lithiated PSU was reacted with 10-undecenoyl chloride to graft PSU with undecenoyl side chains. The second step involved a free-radical thiol–ene coupling reaction between the C=C bonds of the pendant undecenoyl chains and 2-(2-benzimidazolyl)ethan
A 2-y nationwide survey of patients in Denmark with non-tuberculous mycobacteria (NTM) cultures was undertaken. Patients were identified by means of records held at the International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Denmark. The objectives were to identify isolated NTM to species level, to describe the incidence of the various species and to evaluate the clinical s
BACKGROUND: Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths in the Western world, and despite the fact that metastases are usually the ultimate cause of deaths, the knowledge of the genetics of advanced stages of this disease is limited. In order to identify potential genetic abnormalities underlying the development of local and distant metastases in CRC patients,
The effect of warmer climate on the depletion of snow-covered area has been evaluated for the Satluj River basin located in the western Himalayan region in India. Snowmelt runoff contributes substantially to the annual streamflow of this river. In order to study the impact of three warming scenarios (T+1, T+2 and T+3degreesC), more than 160 new snow depletion curves were prepared for different ele
Severely deficient activity of the von Willebrand Factor (VWF) cleaving metalloprotease,ADAMTS 13, is associated with thrombotic thrombocytopenic purpura (TTP). The mutation spectrum ofADAMTS 13 is rather heterogeneous, and numerous mutations spread across the gene have been described in association with congenital TTP. The 4143insA mutation is unusual with respect to its geographic concentration.
The objective of the study was to determine the influence of potato variety, weight and storage time after lifting on the glycaemic index (GI) and resistant starch (RS) content predicted from measurement of the rate and extent of in vitro starch hydrolysis, respectively. The potatoes were either boiled, or boiled and subjected to different heat-cycling conditions selected to promote retrogradation
Turner syndrome (TS) is caused by a sex chromosome aberration. The aim was to study the prevalence and incidence of thyroid disease in adults with TS. Women with TS (n = 91; mean age, 37.7 +/- 11 yr) were compared with an age-matched female random population sample (n = 228). At baseline, 15 (16%) TS women were treated for hypothyroidism, and elevated serum TSH was found in another eight (9%). As
BACKGROUND: Oxazolone-induced colitis in the rat is an immune-driven model of human colitis. The aim of the present study was to measure the changes in the absorptive and exudative permeabilites, oedema formation, and local blood flow in this model during the development of inflammation. We also assessed the effects of acute (<1 h), topical glucocorticosteroid (GCS) treatment on these factors. MET
Purpose: The puspose with our essay is to investigate how an acquisition can affect leadership. We want to specialize us by analysing how a leadership and the employees in a smaller company can be affected by an acquisition by a larger organization. We also want to investigate how a good leadership should be in a small company due to an acquisition. Methodology: This essay is based on a qualitativ
The landscape composition in Sweden has drastically changed during recent years. Intensified farming and forestry has led to reduced areas valuable for biodiversity and a decline of biodiversity across many organism groups. In Sweden almost 30% of all day-living butterflies are considered threatened. Habitat creation as a by-product of anthropogenic activities may provide new habitats for species
Background: Cytokine response is an important factor in the development of shock and organ failure. The aim of this study was to investigate intraperitoneal (peritoneal) and venous (systemic) postoperative cytokine release after major surgery. Methods: Major abdominal surgery was performed in 19 patients. Preoperative systemic measurements and postoperative systemic and peritoneal measurements of
Objective: To evaluate the effects of a single-session, interactive computer-based educational program on knowledge, compliance and quality of life in heart failure patients with special emphasis on gender differences. Methods: One hundred and fifty-four patients, mean age 70 years, from five heart failure clinics were randomised to either receiving only standard education (n = 72) or standard edu
